Patents by Inventor Robert Ruhfel

Robert Ruhfel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA recombination junction detection
    Patent number: 9605322
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: March 28, 2017
    Assignee: Cepheid
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • DNA RECOMBINATION JUNCTION DETECTION
    Publication number: 20140248624
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Application
    Filed: January 7, 2014
    Publication date: September 4, 2014
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • DNA recombination junction detection
    Patent number: 8652784
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: February 18, 2014
    Assignee: Cepheid
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • DNA RECOMBINATION JUNCTION DETECTION
    Publication number: 20130065774
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 14, 2013
    Applicant: Cepheid
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • DNA recombination junction detection
    Patent number: 8187812
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: May 29, 2012
    Assignee: Cepheid
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • DNA recombination junction detection
    Publication number: 20090047669
    Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
    Type: Application
    Filed: May 11, 2007
    Publication date: February 19, 2009
    Applicant: Cepheid
    Inventors: Jian Ping Zhang, Ernest Jay Friedlander, Robert Ruhfel, David Douglas Swenson, Alan Thomas Wortman
  • Electrophoretic nucleic acid purification method
    Patent number: 6827830
    Abstract: An electrophoretic method for purifying a nucleic acid sample is disclosed. According to the method, the electrophoresis is effective to substantially reduce the concentration of contaminants relative to the concentration of desired nucleic acid in the nucleic acid sample, thereby producing a purified nucleic acid. In the method, the loading and recovery wells may be the same or different, and the electric fields may be DC or alternating.
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: December 7, 2004
    Assignees: Applera Corporation, University of Ottawa
    Inventors: Gary Slater, J. William Efcavitch, Guy Drouin, Pascal Mayer, Jean Rousseau, Hong Yan Zhou, Claudia Chiesa, Robert Ruhfel, Roger O'Neill
  • Electrophoretic nucleic acid purification method
    Patent number: 6146511
    Abstract: An electrophoretic method for purifying a nucleic acid sample is disclosed. The method generally comprises the steps of (1) providing a nucleic acid sample comprising a desired nucleic acid and one or more contaminants, (2) providing an electrophoresis matrix having a loading well and a recovery well formed therein, (3) placing the nucleic acid sample into the loading well, (4) performing a first electrophoresis comprising electrophoresing the nucleic acid sample for a first time effective to transport the desired nucleic acid out of the loading well and into the electrophoresis matrix; and (5) performing a second electrophoresis comprising electrophoresing the nucleic acid sample for a second time effective to transport the desired nucleic acid out of the electrophoresis matrix and into the recovery well.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: November 14, 2000
    Assignees: The Perkin-Elmer Corporation, The University of Ottawa
    Inventors: Gary Slater, J. William Efcavitch, Guy Drouin, Pascal Mayer, Jean Rousseau, Hong Yan Zhou, Claudia Chiesa, Robert Ruhfel, Roger O'Neill