Patents by Inventor Robert S. Abrams

Robert S. Abrams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10850042
    Abstract: A three-position plunger is provided including a sleeve having an opening at a distal end, a pre-load cavity proximal to and in communication with the opening, a first cavity proximal to and in communication with the pre-load cavity, a second cavity proximal to and in communication with the pre-load cavity, and at least one rib. The rib(s) is generally aligned with the first cavity. The plunger further includes an insert configured to be displaced from the pre-load cavity to the first cavity and from the first cavity to the second cavity. The insert is configured to provide support for the compression of the rib(s) when the insert is positioned in the first cavity.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: December 1, 2020
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Jean-Pierre Giraud, Bernard Sol, Robert J. Pangborn, Robert S. Abrams, Joseph W. Rogers, Peter J. Sagona, Michael J. Mims
  • Publication number: 20200270025
    Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
    Type: Application
    Filed: March 2, 2020
    Publication date: August 27, 2020
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Patent number: 10577154
    Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: March 3, 2020
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Patent number: 10561795
    Abstract: A convertible plunger is provided comprising an internal portion and a generally cylindrical exterior surface. At least a portion of the exterior surface is maintained in an initial expanded state by a property of the internal portion. The expanded state is reducible to a constricted state by an operation that is applied to the internal portion of the plunger to alter the property. A film coating may also be applied to a sidewall of the sleeve to reduce a sliding friction between the sleeve and barrel. A film coating may also be applied to a nose cone of the plunger to provide a barrier between the plunger and product in the barrel.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: February 18, 2020
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Jean-Pierre Giraud, Bernard Sol, Robert J. Pangborn, Robert S. Abrams, Joseph W. Rogers, Peter J. Sagona, Michael J. Mims
  • Patent number: 10537273
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier and lubricity coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system is also disclosed.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 21, 2020
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20190352778
    Abstract: A syringe or other vessel having a substrate surface coated by PECVD is provided. The PECVD coating is made by generating plasma from a gaseous reactant comprising an organosilicon precursor and optionally O2. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma. In particular, a lubricity coating made by said method is provided. Vessels coated by said method and the use of such vessels protecting a compound or composition contained or received in said coated vessel against mechanical and/or chemical effects of the surface of the uncoated vessel material are also provided.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 21, 2019
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20190344018
    Abstract: A method and apparatus for plasma modifying a workpiece such as a syringe barrel, cartridge barrel, vial, or blood tube is described. Plasma is provided within the lumen of the workpiece. The plasma is provided under conditions effective for plasma modification of a surface of the workpiece. A magnetic field is provided in at least a portion of the lumen. The magnetic field has an orientation and field strength effective to improve the uniformity of plasma modification of the interior surface of the generally cylindrical wall. A vessel made according to the process or using the apparatus described above. A pharmaceutical package comprising the syringe barrel or vial containing a pharmaceutical preparation, secured with a closure.
    Type: Application
    Filed: July 24, 2019
    Publication date: November 14, 2019
    Inventors: Christopher Weikart, Becky L. Clark, Adam Stevenson, Robert S. Abrams, John Belfance
  • Publication number: 20190328299
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier and lubricity coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system is also disclosed.
    Type: Application
    Filed: July 8, 2019
    Publication date: October 31, 2019
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Patent number: 10390744
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier and lubricity coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system is also disclosed.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: August 27, 2019
    Assignee: SiO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Patent number: 10392236
    Abstract: Example string reels with level wind apparatus are disclosed herein. An example level wind apparatus includes a guide to direct a line onto or away from a reel when the reel is rotating. The reel is rotatable in a first direction to wind the line onto the reel and the reel is rotatable in a second direction to unwind the line from the reel. The level wind apparatus also includes a tensioner to create tension in the line while the reel is rotating the second direction.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: August 27, 2019
    Assignee: The Boeing Company
    Inventors: Robert Fordice, Shawn A. McAuley, Craig Ericksen, Jourdon S. Abrams
  • Publication number: 20190233167
    Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
    Type: Application
    Filed: December 19, 2018
    Publication date: August 1, 2019
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Patent number: 10363370
    Abstract: A method and apparatus for plasma modifying a workpiece such as a syringe barrel, cartridge barrel, vial, or blood tube is described. Plasma is provided within the lumen of the workpiece. The plasma is provided under conditions effective for plasma modification of a surface of the workpiece. A magnetic field is provided in at least a portion of the lumen. The magnetic field has an orientation and field strength effective to improve the uniformity of plasma modification of the interior surface of the generally cylindrical wall. A vessel made according to the process or using the apparatus described above. A pharmaceutical package comprising the syringe barrel or vial containing a pharmaceutical preparation, secured with a closure.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: July 30, 2019
    Assignee: SiO2 Medical Products, Inc.
    Inventors: Christopher Weikart, Becky L. Clark, Adam Stevenson, Robert S. Abrams, John Belfance
  • Publication number: 20190125976
    Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and assembling them into syringes, e.g., pre-filled syringes.
    Type: Application
    Filed: January 13, 2017
    Publication date: May 2, 2019
    Inventors: Brian Russell Lilly, Kenneth Wade Kelly, Joseph W. Rogers, Jean-Pierre Giraud, Bruce RABINNE, Herve Pichot, Benjamin Hunt, Zachary Dean Freeman, Dalton Roe, Robert S. Abrams
  • Patent number: 10201660
    Abstract: A method and apparatus for plasma modifying a workpiece such as a medical barrel, medical barrel, vial, or blood tube is described. Plasma is provided within the lumen of the workpiece. The plasma is provided under conditions effective for plasma modification of a surface of the workpiece. A magnetic field is provided in at least a portion of the lumen. The magnetic field has an orientation and field strength effective to improve the uniformity of plasma modification of the generally cylindrical interior surface 16 of the generally cylindrical interior surface 16.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: February 12, 2019
    Assignee: SiO2 Medical Products, Inc.
    Inventors: Christopher Weikart, Becky L. Clark, Adam Stevenson, Robert S. Abrams, John Belfance, Joseph A. Jones, Thomas E. Fisk
  • Patent number: 10189603
    Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting a composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: January 29, 2019
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Publication number: 20180304020
    Abstract: A package including a vessel wherein at least a portion of the vessel wall is made of a double wall material is disclosed. The double wall material comprises an interior polymer layer enclosed by an exterior polymer layer and one of the polymer layers is a layer made of cyclic olefin polymer (COP) resin. The package comprising the double wall, a CVD coating set on the wall, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
    Type: Application
    Filed: November 28, 2017
    Publication date: October 25, 2018
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20180117255
    Abstract: A method and apparatus for plasma modifying a workpiece such as a syringe barrel, cartridge barrel, vial, or blood tube is described. Plasma is provided within the lumen of the workpiece. The plasma is provided under conditions effective for plasma modification of a surface of the workpiece. A magnetic field is provided in at least a portion of the lumen. The magnetic field has an orientation and field strength effective to improve the uniformity of plasma modification of the interior surface of the generally cylindrical wall. A vessel made according to the process or using the apparatus described above. A pharmaceutical package comprising the syringe barrel or vial containing a pharmaceutical preparation, secured with a closure.
    Type: Application
    Filed: September 1, 2017
    Publication date: May 3, 2018
    Inventors: Christopher Weikart, Becky L. Clark, Adam Stevenson, Robert S. Abrams, John Belfance
  • Patent number: 9878101
    Abstract: A package including a vessel made of cyclic olefin polymer (COP) resin, a CVD coating on a vessel, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: January 30, 2018
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20170296756
    Abstract: A three-position plunger is provided including a sleeve having an opening at a distal end, a pre-load cavity proximal to and in communication with the opening, a first cavity proximal to and in communication with the pre-load cavity, a second cavity proximal to and in communication with the pre-load cavity, and at least one rib. The rib(s) is generally aligned with the first cavity. The plunger further includes an insert configured to be displaced from the pre-load cavity to the first cavity and from the first cavity to the second cavity. The insert is configured to provide support for the compression of the rib(s) when the insert is positioned in the first cavity.
    Type: Application
    Filed: October 14, 2014
    Publication date: October 19, 2017
    Inventors: Jean-Pierre Giraud, Bernard Sol, Robert J. Pangborn, Robert S. Abrams, Joseph W. Rogers, Peter J. Sagona, Michael J. Mims
  • Patent number: D870278
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: December 17, 2019
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Brian Russell Lilly, Dalton Roe, Zachary Dean Freeman, Benjamin Hunt, Kenneth Wade Kelly, Robert S. Abrams