Patents by Inventor Robert S. Chao

Robert S. Chao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070249674
    Abstract: The invention relates to crystalline free base forms of biphenyl-2-ylcarbamic acid 1-[2-(4-{[(R)-2-(3-formylamino-4-hydroxyphenyl)-2-hydroxyethylamino]methyl}-2,5-dimethylphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. This invention also relates to pharmaceutical compositions containing or prepared from such crystalline forms; processes and intermediates useful for preparing such crystalline forms; and methods of using such crystalline forms to, for example, treat a pulmonary disorder.
    Type: Application
    Filed: April 24, 2007
    Publication date: October 25, 2007
    Inventors: Jennifer Bolton, Robert S. Chao, Miroslav Rapta, Lisa Williams, Richard D. Wilson
  • Publication number: 20040138200
    Abstract: A pharmaceutical composition comprising a salt, preferably a crystalline salt, of an organic acid of low water solubility and a compound of formula (I) is provided. The salts are useful in treating Parkinson's disease. Also provided are methods of treatment using the salts and methods of making crystalline forms of the salts.
    Type: Application
    Filed: October 2, 2003
    Publication date: July 15, 2004
    Inventors: Michael Hawley, Michael S. Bergren, Phillip R. Nixon, Gordon W. Halstead, Robert S. Chao, Tzu-chi R. Ju
  • Publication number: 20030073826
    Abstract: A processes for preparing crystalline clindamycin free base is provided.
    Type: Application
    Filed: August 26, 2002
    Publication date: April 17, 2003
    Inventors: Robert S. Chao, Michael Hawley, Lisa M. Reeder, Donald P. Jones
  • Publication number: 20030073648
    Abstract: The antibiotic drug clindamycin is provided as a crystalline free base. Three polymorphic/pseudopolymorphic forms of crystalline clindamycin free base are disclosed. Also provided are pharmaceutical compositions comprising crystalline clindamycin free base. Processes for preparing crystalline clindamycin free base and compositions thereof are also provided along with methods for treating medical conditions with the pharmaceutical compositions.
    Type: Application
    Filed: August 26, 2002
    Publication date: April 17, 2003
    Inventors: Robert S. Chao, Michael Hawley, Lisa M. Reeder, Donald P. Jones
  • Publication number: 20030073647
    Abstract: A processes for preparing crystalline clindamycin free base is provided.
    Type: Application
    Filed: August 26, 2002
    Publication date: April 17, 2003
    Inventors: Robert S. Chao, Michael Hawley, Lisa M. Reeder, Donald P. Jones
  • Publication number: 20020197320
    Abstract: A suppository composition and method for rectal administration of a lincosamide antibacterial drug, such as clindamycin, lincomycin, or pirlimycin, is disclosed. The composition is a rectal suppository containing an antimicrobially effective amount of the lincosamide in particulate form dispersed in a Hard Fat suppository base, preferably a Hard Fat NF suppository base. The most preferred suppository compositions of the present invention have long term storage stability, while maintaining effectiveness against bacterial infections.
    Type: Application
    Filed: February 5, 2002
    Publication date: December 26, 2002
    Inventors: Lorraine E. Pena, Phil B. Bowman, Robert S. Chao, Carolyn V. Pesheck, Clayton W. Jacobsen
  • Patent number: 5721359
    Abstract: Anhydrous and crystalline free acid form of the cephalosporin antiobiotic ceftiofur, processes for its manufacture, and pharmaceutical composition containing it are provided.
    Type: Grant
    Filed: September 11, 1995
    Date of Patent: February 24, 1998