Abstract: Method for determining positive entrainment sites for mapping active reentrant circuits, including the procedures of measuring a pre-entrainment cycle length at at least one cardiac site, measuring a post-pacing interval (PPI) at the cardiac site, determining a difference between the PPI and the pre-entrainment cycle length and annotating the cardiac site according to the determined difference.

Abstract: Method for determining positive entrainment sites for mapping active reentrant circuits, including the procedures of measuring a pre-entrainment cycle length at least one cardiac site, measuring a post-pacing interval (PPI) at the cardiac site, determining a difference between the PPI and the pre-entrainment cycle length and annotating the cardiac site according to the determined difference.

Abstract: Left atrial appendage (LAA) occlusion device including a membrane, a plurality of fixation splines, at least two electrical conductors and an interconnect, the interconnect positioned in the membrane for coupling the fixation splines and the electrical conductors, the fixation splines for affixing the LAA occlusion device to an ostium of the LAA and the electrical conductors for applying high voltage electricity to the ostium of the LAA, wherein the membrane physically occludes the LAA and the electrical conductors are used to electroporate the ostium of the LAA via the high voltage electricity, thereby electrically isolating the LAA.

Abstract: An encapsulation configuration for electronic components in a flexible implantable medical device, including at least one set of folded circuit boards and a filler material, the set of folded circuit boards including a plurality of circuit boards and a plurality of connection cables, each one of the circuit boards including at least one electronics component, each one of the circuit boards having a generally rectangular shape, the connection cables electrically coupling adjacent ones of the circuit boards and the circuit boards being folded over one another in a pleated manner, the filler material surrounding the set of folded circuit boards, the filler material and the set of folded circuit boards together having a cylindrical shape, the set of folded circuit boards being positioned lengthwise in the cylindrical shape and the electronics component being positioned on the set of folded circuit boards to achieve optimal volume consumption in the electronics encapsulation.

Abstract: Method for determining positive entrainment sites for mapping active reentrant circuits, including the procedures of measuring a pre-entrainment cycle length at at least one cardiac site, measuring a post-pacing interval (PPI) at the cardiac site, determining a difference between the PPI and the pre-entrainment cycle length and annotating the cardiac site according to the determined difference.

Abstract: An encapsulation configuration for electronic components in a flexible implantable medical device, including at least one set of folded circuit boards and a filler material, the set of folded circuit boards including a plurality of circuit boards and a plurality of connection cables, each one of the circuit boards including at least one electronics component, each one of the circuit boards having a generally rectangular shape, the connection cables electrically coupling adjacent ones of the circuit boards and the circuit boards being folded over one another in a pleated manner, the filler material surrounding the set of folded circuit boards, the filler material and the set of folded circuit boards together having a cylindrical shape, the set of folded circuit boards being positioned lengthwise in the cylindrical shape and the electronics component being positioned on the set of folded circuit boards to achieve optimal volume consumption in the electronics encapsulation.

Abstract: A method for subcutaneously implanting a heart device in a patient using an implantation device involves making a first incision in the vicinity of the sternum of the patient and a second incision in the lumbar region of the patient posterior to the vertebral column of the patient. The implantation device is inserted through the first incision to the second incision, and a guidewire is placed through the implantation device via the second incision to the first incision. An end of the guidewire is coupled to the heart device, and the guidewire is pulled through the implantation device until the guidewire is placed within the patient. The guidewire then is detached from the heart device, and the implantation device is removed. The first and second incisions are sutured such that the heart device is left positioned completely subcutaneously around the heart and outside of the ribcage of the patient.

Abstract: Injectable subcutaneous heart device (ISHD) for regulating arrhythmias in a heart of a patient, including a plurality of linked structures, each one of the linked structures being hollow, an interconnecting bus, a biocompatible coating, at least two electrodes and a plurality of sensors, the interconnecting bus for electrically coupling the linked structures and the biocompatible coating for hermetically sealing and electrically insulating the linked structures, one of the linked structures encapsulating a power source, another one of the linked structures encapsulating at least one capacitor and a third one of the linked structures encapsulating electronics, the electrodes and the sensors being respectively placed on an outer surface of the linked structures located at opposite ends of the ISH D, for detecting arrhythmias and providing electrical shocks to the heart, the electrodes and the sensors being electrically coupled with the interconnecting bus and the ISHD being positioned subcutaneously around the

Abstract: Encapsulation configuration for electronic components in a flexible implantable medical device, including a first encapsulation section and a second encapsulation section, the first encapsulation section including a plurality of circuit boards (CBs), each CB including at least one electronics component and a plurality of connection cables, wherein each CB has a generally circular shape and wherein each connection cable electrically couples adjacent ones of the plurality of CBs alternatively at opposite ends, thereby giving the encapsulation configuration an accordion like shape when folded, the second encapsulation section including a flat CB, including a plurality of electronics components, wherein the flat CB has a generally rectangular shape, wherein the plurality of electronics components are positioned on both sides of the flat CB with taller ones of the plurality of electronics components positioned closer to the center of the flat CB and shorter ones of the plurality of electronics components positione

Abstract: A method for operating a pacemaker comprises the procedures of building a database of a cardiac cycle of a patient suffering from bundle branch block and artificially pacing a ventricle of the patient using the pacemaker according to anticipative atrioventricular (AV) delays in the database which are based on measured P-P intervals in the database.

Abstract: Method for operating a pacemaker comprising the procedures of building a database of a cardiac cycle of a patient suffering from bundle branch block and artificially pacing a ventricle of the patient using the pacemaker according to anticipative atrioventricular (AV) delays in the database which are based on measured P-P intervals in the database.

Abstract: Injectable subcutaneous heart device (ISHD) for regulating arrhythmias in a heart of a patient, including a plurality of linked structures, each one of the linked structures being hollow, an interconnecting bus, a biocompatible coating, at least two electrodes and a plurality of sensors, the interconnecting bus for electrically coupling the linked structures and the biocompatible coating for hermetically sealing and electrically insulating the linked structures, one of the linked structures encapsulating a power source, another one of the linked structures encapsulating at least one capacitor and a third one of the linked structures encapsulating electronics, the electrodes and the sensors being respectively placed on an outer surface of the linked structures located at opposite ends of the ISH D, for detecting arrhythmias and providing electrical shocks to the heart, the electrodes and the sensors being electrically coupled with the interconnecting bus and the ISHD being positioned subcutaneously around the

Abstract: The invention involves a system and method for an esophageal cooling system suitable for use during surgical procedures associated with the left atrium of the heart and most particularly ablation procedures associated with atrial fibrillation. The esophageal cooling system is suitable for use irrespective of whether the ablation procedure is intraoperative or catheter based. The system includes an esophageal catheter constructed and arranged to fit within the patients esophagus. Suitably located along the esophageal catheter is a phoximal balloon for occluding an upper portion of the esophagus. The phoximal balloon includes a coolant lumen for transferring temperature controlled liquid to the area where the esophagus may be in contact with the atrium of the heart. The liquid is expelled through a nozzle which directs the liquid to the inner surface of the esophagus.

Abstract: The present invention provides a pacing device and method that allows for preferential right atrial, at or near the His bundle, and ventricular pacing, either individually or in combination, including tri-ventricular pacing. The pacing device includes a power source and one or more logic circuits allowing for programmable delivery of pacing to any combination of the right atria, the para-Hisian region, and the right and/or the left ventricles. The pacing device allows the user to select which site(s) to pace as well at the appropriate relative timing of pacing impulse delivery to any of these three previously mentioned sites. The device is constructed and arranged to be combined with an atrial sensing/pacing electrode to allow for atrio-ventricular sequential tri-ventricular pacing or variants of such. Also, a defibrillator lead can be incorporated into the device to allow for protection from ventricular arrhythmias and sudden death.

Abstract: The current invention describes a method and system to measure and validate the efficacy of cardiac resynchronization therapy pacing using electroanatomical position and motion sensing during the various phases of the cardiac cycle. In this method, electroanatomical position and motion sensors are utilized with sensing from the tip of both right ventricular pacing lead and left ventricular pacing lead. An operator can therefore obtain data not currently available to an implanter with current technology. This data includes the physical distance between both leads and the relative motion of both leads during cardiac resynchronization therapy biventricular pacing. If good lead positioning for both the right ventricular lead and left ventricular lead has been obtained, then the operator will be able to demonstrate good synchronization of the cardiac cycle.

Abstract: A method and apparatus are provided for addressing vascular stenotic lesions. The geometry of a stenotic lesion zone is determined and is used to determine pressure drop of blood flow across the lesion zone or a portion thereof. The pressure drop value is used to determine a treatment regimen for the stenotic lesion zone. The geometry if preferably a three dimensional geometry. The apparatus provides pressure drop values to a physician so the physician can treat the patient if treatment is needed and provides direction for treatment options as to type and degree.

Abstract: A method and apparatus for performing medical treatment on a patient. The method include generating a three dimensional image of a portion of a patient and overlaying a real time image of a treatment tool in the patient during its movement in the patient to a site of interest.

Abstract: The invention involves a system and method for an esophageal cooling system suitable for use during surgical procedures associated with the left atrium of the heart and most particularly ablation procedures associated with atrial fibrillation. The esophageal cooling system is suitable for use irrespective of whether the ablation procedure is intraoperative or catheter based. The system includes an esophageal catheter constructed and arranged to fit within the patients esophagus. Suitably located along the esophageal catheter is a phoximal balloon for occluding an upper portion of the esophagus. The phoximal balloon includes a coolant lumen for transferring temperature controlled liquid to the area where the esophagus may be in contact with the atrium of the heart. The liquid is expelled through a nozzle which directs the liquid to the inner surface of the esophagus.