Patents by Inventor Robert S. Hillman

Robert S. Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10288630
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: May 14, 2019
    Assignee: C A Casyso GmbH
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20190113500
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: November 27, 2018
    Publication date: April 18, 2019
    Inventors: Cory Lee McCluskey, Robert S. Hillman, Michael Gorin, Hubert Martin Schwaiger
  • Publication number: 20190015828
    Abstract: Embodiments of a platelet testing system include an analyzer console device and a blood testing cartridge configured to releasably install into the console device. The cartridge device is configured with one or more measuring chambers and one or more mixing chambers that are fluidically connected within the cartridge device that enable the mixing of saline and a blood sample to a desired dilution. Additionally, the cartridge device is further configured with a cartridge slider that provides a reagent bead to the saline and blood mixture at a desired time. As such, one or more platelet activation assays can be conducted by measuring, through cartridge electrodes of the cartridge device, the detectable changes in platelet activity within the blood and saline mixture.
    Type: Application
    Filed: July 12, 2017
    Publication date: January 17, 2019
    Inventors: Michael M. Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Patent number: 10175225
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: January 8, 2019
    Assignee: C A Casyso AG
    Inventors: Cory Lee McCluskey, Robert S. Hillman, Michael Gorin, Hubert Martin Schwaiger
  • Publication number: 20180059125
    Abstract: Embodiments of a blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. In some embodiments, the blood coagulation testing system includes a single-use cartridge component configured to measure and mix reagents with blood received from a blood sample reservoir. A mixing chamber in the single-use cartridge includes different reagent beads that, when exposed to a pre-determined volume of blood, dissolve and mix specific reagents with the blood. The assembled blood cartridge further includes configurations that are designed to prevent blood from prematurely mixing with reagent beads in the mixing chamber and to guide blood flow in the mixing chamber to dissolve reagent beads in a desired order. Thus, the mixture obtained from the mixing chamber can be readily utilized to generate results for the blood coagulation testing system.
    Type: Application
    Filed: August 31, 2016
    Publication date: March 1, 2018
    Inventors: Michael M. Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Patent number: 9897618
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: February 20, 2018
    Assignee: C A Casyso GmbH
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20160091515
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 31, 2016
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20160091483
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: September 29, 2014
    Publication date: March 31, 2016
    Inventors: Cory Lee McCluskey, Robert S. Hillman, Michael Gorin, Hubert Martin Schwaiger
  • Publication number: 20160091517
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 31, 2016
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20160091516
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 31, 2016
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20160091514
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 31, 2016
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
  • Publication number: 20100036310
    Abstract: An integrated patient monitoring and control system is provided which includes a sample set, the sample set being adapted for coupling to the patient to obtain a specimen from the patient, a sensor, the sensor being adapted to receive the specimen from the sample set and to analyze the sample, a medication control unit, the medication control unit receiving information from the sensor, and utilizing that information to determine medication dosing information for the patient, and a medication administration system, the medication administration system receiving the dosing information from the medication control unit, and adapted to cause administration of the medication to the patient. If the sample set is adapted for blood draw, the system advantageously is performed in conjunction with a pneumatic pressure cuff, inflated so as to aid in blood draw.
    Type: Application
    Filed: August 3, 2009
    Publication date: February 11, 2010
    Inventor: ROBERT S. HILLMAN
  • Patent number: 5922551
    Abstract: Methodology which avoids the problems associated with interference from whole blood is provided for instrumented determination of platelet binding function. Particularly, small particles to which fibrinogen is bound, and which contain an infrared light absorbing dye, are used to determine the binding of platelets in a whole blood sample to the fibrinogen. Agglutination of the platelets with the coated particles is determined by a change in infrared light absorption characteristics.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: July 13, 1999
    Assignee: Accumetrics, Inc.
    Inventors: Dennis A. Durbin, Theodore T. Lee, Boris I. Ratnikov, Robert S. Hillman, Jeffrey W. Smith
  • Patent number: 5733259
    Abstract: A closed-loop drug delivery system uses patient response and rule based decision making methods to achieve operator specified responses for diagnostic purposes. In the preferred embodiment, cardiac diagnosis is performed by pharmacologically stressing the heart by administration of an exercise simulating agent drug. In the preferred method, a protocol is defined, which preferably includes a target for a physiologic variable, such as heart rate, and a plan to achieve that target value. Preferably, the plan includes a specification of the desired rate of increase in that variable, such as the rate of increase in the heart rate per minute. The plan comprises the desired changes in the physiologic variable as a function of time. While any desired function may be used, the more common modes include RAMP, HOLD, LEVEL and TARGET mode. In one aspect of this invention, the protocol may be varied by the operator after drug administration has begun.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: March 31, 1998
    Assignee: Gensia Pharmaceuticals, Inc.
    Inventors: Christian P. Valcke, Walter J. Bochenko, Robert S. Hillman
  • Patent number: 5697899
    Abstract: A feedback controlled drug delivery system includes automated blood sampling and analysis and dosing of the patient. Automated sampling is performed by direct analysis of patient blood, such as for measurement of its coagulation state. A novel manifold includes a fluid input port, a patient port adapted to output fluid and to receive a blood sample from the patient, and a fluid pathway connecting the fluid port and the patient port. A sample line is connected to the fluid pathway to provide the sample to an analyzer. In one aspect of this invention, the sample is forced through the sample line by isolating the patient port, such as by a valve, and non-drug fluid is forced into the manifold causing the blood to cross through the sample line. Alternately, a pump force may be utilized on the sample line. In another aspect of this invention, a positive interlock system is utilized between a drug source and the system.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: December 16, 1997
    Assignee: Gensia
    Inventors: Robert S. Hillman, Christian P. Valcke, Robert T. Gauthier
  • Patent number: 5383848
    Abstract: Methods, formulations, and a system for improved iontophoretic administration of a drug, by, preferably, topical administration of a formulation containing an active vasodilator, rubefacient, or counterirritant agent such as capsaicin on the skin at the electrode site, or, iontophoretic administration of a vasodilator formulation or alpha blocker prior to iontophoretic administration of the drug.
    Type: Grant
    Filed: April 4, 1991
    Date of Patent: January 24, 1995
    Assignee: Gensia, Inc.
    Inventors: Robert S. Hillman, John M. Pawelchak
  • Patent number: 5300779
    Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
    Type: Grant
    Filed: August 18, 1992
    Date of Patent: April 5, 1994
    Assignee: Biotrack, Inc.
    Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
  • Patent number: 5204525
    Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
    Type: Grant
    Filed: July 19, 1991
    Date of Patent: April 20, 1993
    Assignee: Biotrack
    Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
  • Patent number: 5164598
    Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
    Type: Grant
    Filed: February 5, 1991
    Date of Patent: November 17, 1992
    Assignee: Biotrack
    Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
  • Patent number: D777343
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: January 24, 2017
    Assignee: C A Casyso AG
    Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey