Patents by Inventor Robert S. Hoerrner

Robert S. Hoerrner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing dibenzocycloheptene compounds
    Patent number: 5932767
    Abstract: Protriptyline can be prepared from 5-dihydrodibenzocycloheptatriene, by deprotonation, followed by reaction at low temperatures with 1,3-bromochloropropane to give the 5-(chloropropyl)-dibenzocycloheptatriene, which is reacted with methylamine in a displacement reaction to give the protriptyline product.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: August 3, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Robert S. Hoerrner, Joseph Auerbach, John Carolan
  • Reductive amination process
    Patent number: 5508404
    Abstract: A process of reductive amination efficiently yields an HIV protease inhibitor.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: April 16, 1996
    Assignee: Merck & Co., Inc.
    Inventors: David Askin, Steven J. Cianciosi, Robert S. Hoerrner
  • Process for the preparation of antiulcer agents
    Patent number: 5391752
    Abstract: Anti-ulcer agents having a methylsulfinyl bridge between a substituted pyridine moiety and a substituted benzimidazole moiety are prepared by oxidizing the corresponding compounds, having a methylthio bridge, with magnesium monoperoxyphthalate in a suitable solvent. The reaction may be run in an aromatic hydrocarbon solvent, wherein the product may crystallize out of the reaction solution and may be directly isolated by filtration.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: February 21, 1995
    Assignee: Merck & Co., Inc.
    Inventors: Robert S. Hoerrner, Joel J. Friedman, Joseph S. Amato, Thomas M. Liu, Ichiro Shinkai, Leonard M. Weinstock