Patents by Inventor Robert S. Marmor

Robert S. Marmor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing buprenorphine
    Patent number: 10208054
    Abstract: An improved process for preparing buprenorphine and a method for increasing the yield of buprenorphine or a derivative thereof.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: February 19, 2019
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Nicolas Archer, David August, Michael Bease, Barbara Jamieson, Robert S. Marmor
  • METHOD OF PREPARING BUPRENORPHINE
    Publication number: 20170217978
    Abstract: An improved process for preparing buprenorphine and a method for increasing the yield of buprenorphine or a derivative thereof.
    Type: Application
    Filed: April 17, 2017
    Publication date: August 3, 2017
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Nicolas ARCHER, David AUGUST, Michael BEASE, Barbara JAMIESON, Robert S. MARMOR
  • Method of preparing buprenorphine
    Patent number: 9624231
    Abstract: An improved process for preparing buprenorphine and a method for increasing the yield of buprenorphine or a derivative thereof.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: April 18, 2017
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Nicolas Archer, David August, Michael Bease, Barbara Jamieson, Robert S. Marmor
  • Morphine Sulfate Methanolic Solvate, Processes for Making Same and Related Compositions and Methods for Treating Pain
    Publication number: 20150361084
    Abstract: Processes for reducing the amount of impurities, especially ?,?-unsaturated ketones (ABUK), in materials containing morphine. Novel compounds, namely low ABUK morphine sulfate methanolic solvate, and a novel crystal form are also described. The method for making morphine sulfate methanolic solvate comprises mixing a morphine free base composition with methanol to form a solution and adding a liquid comprising sulfuric acid to the solution to form a morphine sulfate methanolic solvate precipitate. A method of making a morphine sulfate compound comprises drying the morphine sulfate methanolic solvate in the presence of water vapor, such that methanol molecules are removed and replaced with water vapor molecules. A composition for treating pain comprises the morphine sulfate compound and at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Inventor: Robert S. Marmor
  • Morphine sulfate methanolic solvate, processes for making same and related compositions and methods for treating pain
    Patent number: 9127008
    Abstract: Processes for reducing the amount of impurities, especially ?,?-unsaturated ketones (ABUK), in materials containing morphine. Novel compounds, namely low ABUK morphine sulfate methanolic solvate, and a novel crystal form are also described. The method for making morphine sulfate methanolic solvate comprises mixing a morphine free base composition with methanol to form a solution and adding a liquid comprising sulfuric acid to the solution to form a morphine sulfate methanolic solvate precipitate. A method of making a morphine sulfate compound comprises drying the morphine sulfate methanolic solvate in the presence of water vapor, such that methanol molecules are removed and replaced with water vapor molecules. A composition for treating pain comprises the morphine sulfate compound and at least one pharmaceutically acceptable excipient.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 8, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventor: Robert S. Marmor
  • MORPHINE SULFATE METHANOLIC SOLVATE, PROCESSES FOR MAKING SAME AND RELATED COMPOSITIONS AND METHODS FOR TREATING PAIN
    Publication number: 20140275146
    Abstract: Processes for reducing the amount of impurities, especially ?,?-unsaturated ketones (ABUK), in materials containing morphine. Novel compounds, namely low ABUK morphine sulfate methanolic solvate, and a novel crystal form are also described. The method for making morphine sulfate methanolic solvate comprises mixing a morphine free base composition with methanol to form a solution and adding a liquid comprising sulfuric acid to the solution to form a morphine sulfate methanolic solvate precipitate. A method of making a morphine sulfate compound comprises drying the morphine sulfate methanolic solvate in the presence of water vapor, such that methanol molecules are removed and replaced with water vapor molecules. A composition for treating pain comprises the morphine sulfate compound and at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Johnson Matthey Public Limited Company
    Inventor: Robert S. Marmor
  • METHOD OF PREPARING BUPRENORPHINE
    Publication number: 20140235860
    Abstract: An improved process for preparing buprenorphine and a method for increasing the yield of buprenorphine or a derivative thereof.
    Type: Application
    Filed: October 1, 2012
    Publication date: August 21, 2014
    Applicant: JOHNSON MATTEY PUBLIC LIMITED COMPANY
    Inventors: Nicolas Archer, David August, Michael Bease, Barbara Jamieson, Robert S. Marmor
  • Coversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines
    Patent number: 5597924
    Abstract: The invention is a process for preparing substituted 8-hydroxyquinolines from substituted 8-chloroquinolines.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: January 28, 1997
    Assignee: American Cyanamid Company
    Inventors: Robert S. Marmor, Henry L. Strong