Patents by Inventor Robert S. Neuwirth
Robert S. Neuwirth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8609141Abstract: The present invention pertains to silver ion bearing carriers useful in treating monorrhagia of a mammalian uterus, comprising a physiologically inert, flexible earner, e.g., a coil, bearing a tissue cauterizing amount of a silver ion. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue. The silver ions remaining within the uterine cavity can then be neutralized with a sodium chloride solution delivered to the uterus e.g., by catheter, and the carrier recovered from the uterus.Type: GrantFiled: September 1, 2009Date of Patent: December 17, 2013Assignee: Ablation Products LLCInventor: Robert S. Neuwirth
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Patent number: 8042548Abstract: A method for inducing Fallopian tube blockage as a means for female contraception comprises contacting the inner surface tissue of a Fallopian tube with a silver nitrate bearing substrate and delivering an amount of silver nitrate to the tissue sufficient to induce blockage of the Fallopian tube. At least one silver nitrate bearing bead is introduced through the uterine opening of the Fallopian tube by use of a catheter or other device suitable for manipulating the bead. Alternatively, a plurality of beads can be introduced into the Fallopian tube. In a preferred embodiment, one or more silver nitrate bearing beads are arranged on a string to facilitate later removal of the beads. The method of the present invention delivers an amount of silver nitrate to the tissue sufficient to cause tissue necrosis and blockage of the Fallopian tube.Type: GrantFiled: October 27, 2006Date of Patent: October 25, 2011Assignee: Ethicon, Inc.Inventors: Robert S. Neuwirth, Michel Gensini
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Publication number: 20110159044Abstract: The present invention pertains to silver ion bearing carriers useful in treating monorrhagia of a mammalian uterus, comprising a physiologically inert, flexible earner, e.g., a coil, bearing a tissue cauterizing amount of a silver ion. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue. The silver ions remaining within the uterine cavity can then be neutralized with a sodium chloride solution delivered to the uterus e.g., by catheter, and the carrier recovered from the uterus.Type: ApplicationFiled: September 1, 2009Publication date: June 30, 2011Inventor: Robert S. Neuwirth
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Patent number: 7875297Abstract: A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue.Type: GrantFiled: September 2, 2008Date of Patent: January 25, 2011Assignee: Ablation Products LLCInventor: Robert S. Neuwirth
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Publication number: 20090155367Abstract: The present invention provides a method for inducing Fallopian tube blockage as a means for female contraception. The method comprises contacting the inner surface tissue of a Fallopian tube with a silver nitrate bearing substrate, delivering an amount of silver nitrate to the tissue sufficient to induce blockage of the Fallopian tube. Preferably, the substrate is a bead. In one embodiment, at least one silver nitrate bearing bead is introduced through the uterine opening of the Fallopian tube by use of a catheter or other device suitable for manipulating the bead. Alternatively, a plurality of beads can be introduced into the Fallopian tube. In a preferred embodiment, one or more silver nitrate bearing beads are arranged on a string to facilitate later removal of the beads. The method of the present invention delivers an amount of silver nitrate to the tissue sufficient to cause tissue necrosis and blockage of the Fallopian tube.Type: ApplicationFiled: October 27, 2006Publication date: June 18, 2009Inventors: Robert S. Neuwirth, Michel Gensini
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Publication number: 20090068284Abstract: A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue.Type: ApplicationFiled: September 2, 2008Publication date: March 12, 2009Inventor: Robert S. Neuwirth
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Patent number: 7419687Abstract: A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue.Type: GrantFiled: April 16, 2004Date of Patent: September 2, 2008Assignee: Ablation Products LLCInventor: Robert S. Neuwirth
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Publication number: 20040265390Abstract: A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue.Type: ApplicationFiled: April 16, 2004Publication date: December 30, 2004Inventor: Robert S. Neuwirth
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Patent number: 6197351Abstract: A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cavity. Compositions and methods for delivering medicaments are also disclosed.Type: GrantFiled: September 17, 1997Date of Patent: March 6, 2001Inventor: Robert S. Neuwirth
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Patent number: 6187346Abstract: A method and composition for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a hysteroscope housing a first and a second catheter connected to a catheter into the uterus, distending the uterus by introducing CO2 gas under pressure, delivering a silver nitrate paste to the endometrium through the first catheter and allowing the paste to remain a sufficient amount of time to substantially cauterize the entirety of the tissue lining, particularly the endometrium and delivering an aqueous sodium chloride solution to the uterus through the second catheter thereby neutralizing the silver nitrate and rinsing the uterine cavity.Type: GrantFiled: July 15, 1997Date of Patent: February 13, 2001Assignee: Ablation Products, Inc.Inventor: Robert S. Neuwirth
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Patent number: 6165492Abstract: A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cavity. Compositions and methods for delivering medicaments are also disclosed.Type: GrantFiled: February 18, 1999Date of Patent: December 26, 2000Inventor: Robert S. Neuwirth
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Patent number: 5891457Abstract: A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cavity. Compositions and methods for delivering medicaments are also disclosed.Type: GrantFiled: May 12, 1997Date of Patent: April 6, 1999Inventor: Robert S. Neuwirth
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Patent number: 5704934Abstract: A method and apparatus for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a distendable bladder connected to a catheter into the uterus, distending the bladder by introducing a non-toxic fluid under pressure, heating the fluid by means located internal to the bladder to a temperature of 190.degree. to 215.degree. F. and preferably 210.degree. F. for a period of 4 to 12 minutes and preferably 6 minutes and regulating said apparatus by means located external to the uterus, thereby cauterizing substantially the entirety of the tissue lining, particularly the endometrium. An agitator circulates the fluid within the distendable bladder to help keep the fluid at a uniform temperature.Type: GrantFiled: June 7, 1995Date of Patent: January 6, 1998Inventors: Robert S. Neuwirth, Bolduc R. Bolduc
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Patent number: 5501681Abstract: A method and apparatus for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a distendable bladder connected to a catheter into the uterus, distending the bladder by introducing a non-toxic fluid under pressure, cooling the fluid by means located internal to the bladder to a temperature below 32.degree. F. for a period of about 4 to about 12 minutes and preferably about 6 minutes, thereby cauterizing substantially the entirety of the tissue lining, particularly the endometrium.Type: GrantFiled: November 12, 1993Date of Patent: March 26, 1996Inventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 5492529Abstract: A method and apparatus for necrosing tissue are disclosed. Also disclosed are a method and apparatus for treatment of urinary neck blockage and benign prostate hypertrophy. A catheter provided with a heating means and an inflatable balloon is inserted into the urethra so that the heating means is in proximity to the prostate gland and the inflatable bladder attached to the end of the catheter protrudes into the urinary bladder. The bladder is inflated in the urinary bladder to facilitate positioning of the heating means. The heating means is positioned and is then heated for a period of time sufficient to cause necrosis of the tissue lining of the prostate.Type: GrantFiled: December 18, 1991Date of Patent: February 20, 1996Assignee: Gynelab ProductsInventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 5460628Abstract: A method and apparatus for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a distendable bladder connected to a catheter into the uterus, distending the bladder by introducing a non-toxic fluid under pressure, heating the fluid by means located internal to the bladder to a temperature of 190.degree. to 215.degree. F. and preferably 210.degree. F. for a period of 4 to 12 minutes and preferably 6 minutes and regulating said apparatus by means located external to the uterus, thereby cauterizing substantially the entirety of the tissue lining, particularly the endometrium. An agitator circulates the fluid within the distendable bladder to help keep the fluid at a uniform temperature.Type: GrantFiled: September 30, 1992Date of Patent: October 24, 1995Inventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 5159925Abstract: A method for a laparoscopic cholecystostomy and prostate or gallbladder ablation is disclosed wherein a bladder catheter is inserted into the prostate or gallbladder then heated for a period sufficient to cause cauterization necrosis of the tissue lining of the prostate of gallbladder. Subsequently, the prostate or gallbladder is allowed to drain and is then removed. An apparatus for performing the procedure and a procedure and apparatus for treatment of benign prostate hypertrophy are also disclosed.Type: GrantFiled: January 28, 1991Date of Patent: November 3, 1992Assignee: Gynelab, Inc.Inventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 5105808Abstract: A method and apparatus for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a distendable bladder connected to a catheter into the uterus, distending the bladder by introducing a non-toxic fluid under pressure, heating the fluid by means located internal to the bladder to a temperature of 190.about. to 215.about.F. and preferably 210.about.F. for a period of 4 to 12 minutes and preferably 6 minutes and regulating said apparatus by means located external to the uterus, thereby cauterizing substantially the entirety of the tissue lining, particularly the endometrium.Type: GrantFiled: August 9, 1990Date of Patent: April 21, 1992Assignee: Gynelab ProductsInventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 4949718Abstract: A method and apparatus for effecting necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by introducing an applicator comprising a distendable bladder connected to a catheter into the uterus, distending the bladder by introducing a non-toxic fluid under pressure, heating the fluid by means located internal to the bladder to a temperature of 190.degree. to 215.degree. F. and preferably 210.degree. F. for a period of 4 to 12 minutes and preferably 6 minutes and regulating said apparatus by means located external to the uterus, thereby cauterizing substantially the entirety of the tissue lining, particularly the endometrium.Type: GrantFiled: September 9, 1988Date of Patent: August 21, 1990Assignee: Gynelab ProductsInventors: Robert S. Neuwirth, Lee R. Bolduc
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Patent number: 3996921Abstract: A method and apparatus for use in endoscopic examination of a hollow internal organ, such as hysteroscopic examination of the uterus, includes an inflatable cuff for infusing a pressurized viscous fluid into the interior of the uterine cavity for minimizing distortion of an image of the organ interior viewable through the endoscope. The viscous fluid is an optically clear innocuous liquid having a predetermined viscosity such as between 130 and 300 centistokes at 20.degree. C, and a predetermined optical density, such as a refractive index of 1.3912 at 21.degree. C. This viscous fluid is contained in a self-contained sterile packet reservoir which is removably retained within the inflatable cuff with the viscous fluid being pressurized and released from the reservoir into the endoscope to be infused into the organ interior under the controlled pressure of the inflated cuff surrounding the fluid reservoir packet.Type: GrantFiled: April 17, 1975Date of Patent: December 14, 1976Assignee: Pharmacia Inc.Inventor: Robert S. Neuwirth