Abstract: Pharmaceutical compositions and method using aminergic compounds and complement compounds. Compositions are provided comprising: (a) a subefficacious amount of a non-adrenergic aminergic compound or of an adrenergic antagonist; and (b) a safe and effective amount of a complement compound. Methods are also provided comprising the administration of: (a) a low dose of a non-adrenergic aminergic compound or of any adrenergic antagonist; and (b) a safe and effective amount of a complement compound. Non-adrenergic aminergic compounds can comprise a histaminergic, dopaminergic, muscarinergic, serotoninergic, octopaminergic, or trace aminergic compound. Complement compounds include ascorbates, opioids, polycarboxylic acid chelators, resveratrols, cysteines, substituted derivatives and analogs thereof, and mixtures thereof. Preferred complements include ascorbates, particularly ascorbic acid.

Abstract: Pharmaceutical compositions and method using adrenergic compounds and complement compounds.

Abstract: The present invention provides a process for the treatment of arthritis including the step of administering to an animal or human patient in need of such treatment a plurality of peptides each of which peptides contains a sequence of amino acid residues that is identical to or homologous to residues 110-121 or 152-161 of myelin basic protein. Novel peptides for use in that process are also provided.

Abstract: A torque limiting brake for a heavy duty automotive clutch. The brake, which is keyed to the driven shaft, is engaged by the release mechanism when the clutch is disengaged and moved into engagement with an adjacent stationary surface. This operates to stop the rotation of the driven shaft which tends to continue rotating due to inertia. To prevent damage to the brake when excessive braking pressure is applied, a yieldable connection is provided between the brake inner portion that is keyed to the driven shaft and its outer portion that engages the stationary surface whereby the former can have limited rotation relative to the latter if the braking pressure exceeds a predetermined amount.