Abstract: The present invention relates to novel therapeutic compositions having pharmaceutically effective amounts of pseudoephedrine tannate and dexchlorpheniramine tannate, as well as, in one embodiment, a pharmaceutically effective amount of dextromethorphan tannate. The present invention also encompasses a method of using the novel therapeutic compositions, above, for symptomatically treating and relieving, among other things, the distress of coryza associated with sinusitis, allergic rhinitis, the common cold, and similar discrasias of the upper respiratory tract in affected patients.