Patents by Inventor Robert Sarisky

Robert Sarisky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases
    Publication number: 20080014201
    Abstract: Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNF? antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
    Type: Application
    Filed: April 20, 2007
    Publication date: January 17, 2008
    Inventors: Peter Bugelski, Anuk Das, Donald Griswold, Bailin Liang, Li Li, Robert Sarisky, Xiaozhou Shang
  • TLR3 Glycosylation Site Muteins and Methods of Use
    Publication number: 20070203064
    Abstract: TLR3 glycosylation site muteins, nucleic acids encoding the muteins, and methods of modulating TLR3 activity in a cell are disclosed.
    Type: Application
    Filed: October 30, 2006
    Publication date: August 30, 2007
    Inventors: Karen Duffy, Mark Cunningham, M. Mbow, Robert Sarisky
  • Toll Like Receptor 3 Modulators, Methods and Uses
    Publication number: 20070098716
    Abstract: Toll Like Receptor 3 (TLR3) modulators, such as antibodies, polynucleotides encoding TLR3 antibodies or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: October 27, 2006
    Publication date: May 3, 2007
    Inventors: Karen Duffy, Chong Huang, Roberta Lamb, Mouhamadou Mbow, Robert Sarisky, Lani San Mateo
  • Toll like receptor 3 antagonists, methods and uses
    Publication number: 20060115475
    Abstract: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: November 30, 2005
    Publication date: June 1, 2006
    Inventors: Jill Carton, Shizhong Chen, Mark Cunningham, Anuk Das, Karen Duffy, Jill Giles-Komar, Theresa Goletz, David Knight, Roberta Lamb, Mouhamadou Mbow, Kristen Picha, Gopalan Raghunathan, Lani San Mateo, Robert Sarisky, Vedrana Stojanovic-Susulic, Nicole Stowell, Raymond Sweet, Shanrong Zhao
  • Set of ubiquitous cellular proteins involved in viral life cycle
    Publication number: 20060110404
    Abstract: A method of modulating viral RNA replication and translation, in a eukaryotic cell, of positive-strand viral RNA, comprising the step of contacting a viral RNA-binding protein (vRbp) with a compound that modulates an activity of said protein.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 25, 2006
    Applicant: SmithKline Beecham Corporation
    Inventors: Sven-Erik Behrens, Olaf Isken, Claus Grassmann, Robert Sarisky
  • Hepatitis c virus sub-genomic replicons
    Publication number: 20050250093
    Abstract: The present invention relates generally to the construction of sub-genomic HCV replicon systems that may provide the foundation for generating HCV replicons of all six major genotypes and subtypes to facilitate screening, testing, and evaluating anti-infective agents for HCV disease(s).
    Type: Application
    Filed: April 3, 2003
    Publication date: November 10, 2005
    Inventors: Adam Gates, Baohua Gu, Robert Sarisky
  • Anti-retroviral agents, compositions, methods and uses
    Publication number: 20050136061
    Abstract: HIV gp4l mimetibody polypeptides and encoding polynucleotides are disclosed. Methods of utilizing the polypeptides to reduce or inhibit HIV fusion with a cell membrane and entry into target cells are also disclosed.
    Type: Application
    Filed: December 21, 2004
    Publication date: June 23, 2005
    Inventors: Susan Dillon, Alfred Del Vecchio, Chichi Huang, Karyn O'Neil, Robert Sarisky