Abstract: Disclosed herein, in certain embodiments, is a method for treating an MIF-mediated disorder. In some embodiments, the method comprises administering an active agent that inhibits (i) MIF binding to CXCR2 and CXCR4 and/or (ii) MIF-activation of CXCR2 and CXCR4; (iii) the ability of MIF to form a homomultimer; or a combination thereof.

Abstract: Disclosed herein, in certain embodiments, are methods and compositions for treating inflammatory disorders. In some embodiments, the methods comprise co-administering synergistic combinations of modulators of inflammation.

Abstract: Generation of an intense magnetic field to erase high coercivity magnetic media uses delivery of energy to a degaussing cavity. To conserve energy storage and delivery requirements and to obtain a desired magnetic strength generally uniformly within the cavity, strategic placement of supplemental turns at ends of the magnetic field generating coil wound around the cavity can promote uniformity. Construction of at least cavity ends from an adequate quantity of magnetically soft ferrous material can also promote uniformity. A combination of both approaches is possible.

Abstract: A magnetic field verifier apparatus includes a magnetic field detection element configured to produce a voltage signal in response to an applied magnetic field wherein the voltage signal corresponds to the strength of the applied magnetic field. A current source coupled to the magnetic field detection element provides a stimulating current for the magnetic field detection element that builds in a ramp-like progression. A microcontroller is in communication with the voltage signal wherein the microcontroller is configured to detect and control the ramping time of the magnetic field detection element and to sense after the ramping time the voltage signal from the magnetic field detection element. The magnetic field verifier apparatus is configurable to sense particular field strengths at various frequencies and store the readings to provide the user with a reliable verification that a particular magnetic field strength has been produced in a particular environment.

Abstract: Methods and thermowell systems that can be uses in high dynamic pressure environments. A thermocouple system includes a thermowell configured to enter a structure through which a medium flows; an elongated probe provided partially inside the thermowell and configured to measure a temperature; at least one o-ring disposed around the elongated probe at a first end, the o-ring being configured to dampen a vibration for the elongated probe by contacting the thermowell; and an elastomer disposed around the elongated probe section at a second end, the elastomer being configured to dampen the vibration for the elongated probe by contacting the thermowell.

Abstract: A thermostat (10) includes a housing (11) having a control panel (13) with a plurality of manually selectable input elements or input keys (15) and a display panel (17) for displaying various functions of the programmable thermostat. The programmable thermostat also includes a temperature sensor (18), a microprocessor (19) having memory for storing a default program set of default temperature and time values and a desired program set of desired temperature and time values. The thermostat also includes a “SAVE AWAY” feature or mode of operation. The SAVE AWAY mode is intended to be used so that the HVAC system operates as if the user is away from the house through the manual operation of the SAVE AWAY input key, even though the normal schedule program indicates that the user should be “home”. In use, the SAVE AWAY mode of operation overrides the program set associated with a normal schedule.

Abstract: A thermostat (10) includes a housing (11) having a control panel (13) with a plurality of manually selectable input elements or input keys (15) and a display panel (17) for displaying various functions of the programmable thermostat. The programmable thermostat also includes a temperature sensor (18), a microprocessor (19) having memory for storing a default program set of default temperature and time values and a desired program set of desired temperature and time values. The microprocessor may compare the desired program set to the default program set in order to calculate the efficiency of a HVAC system. The calculated efficiency is then displayed graphically on the display panel.

Abstract: Disclosed herein, in certain embodiments, is a method for treating an inflammatory disorder. In some embodiments, the method comprises administering an active agent that inhibits (i) MIF binding to CXCR2 and CXCR4 and/or (ii) MIF-activation of CXCR2 and CXCR4; (iii) the ability of MIF to form a homomultimer; or a combination thereof.

Abstract: A safety sleeve apparatus comprises a safety sleeve encapsulating a fluorescent tube for protecting the fluorescent tube from physical damage and for preventing the tube from sliding out of the sleeve and breaking if the sleeve is tilted from the horizontal during installation of the tube into a pair of lamp sockets. The sleeve protects the tube from damage if the sleeve is struck by a hard object, and creates an airspace around the tube to protect the tube from cold and prevent the escape of fragments from a broken tube. The sleeve has a greater inside diameter than the outside diameter of the tube. An end cap is mounted on each end of the sleeve, and the end cap includes a cylindrical ring extending upright from the edges of a flat end wall. Projections are included in the cylindrical ring and the projections attach to the slots in the ends of the sleeve.

Abstract: Disclosed herein, in certain embodiments, is a method for treating a cardiovascular disorder. In some embodiments, the method comprises co-administering an inhibitor of inflammation and an agent used to treat a cardiovascular disorder.

Abstract: A surgical guiding instrument for use with a chisel and an implant body for insertion into an intervertebral space, included is a shaft with a stop device for delimiting a depth of insertion of the implant body into the intervertebral space. The shaft has a distal end and a proximal end, the implant body being arranged at the distal end of the shaft and defining two bearing surfaces positionable against the adjacent vertebral bodies, the stop device having at least one stop movably mounted at the distal end of the shaft or on the implant body, the stop having a stop surface pointing in distal direction transversely or substantially transversely to at least one of the bearing surfaces, so that an insertion depth for a surgical machining tool can be set in a simple way.

Abstract: A permanent magnet degausser includes at least one magnetic field generator comprising magnetic elements arranged near a media conveyance path and a conveyor for transporting magnetic media through a magnetic media conveyance path. A passive belt or protector plate may be provided to assist the passage of the magnetic media through the applied magnetic field. The conveyor may be a continuous motion conveyor belt including cleats for holding the magnetic media or a reciprocal media conveyor including magnetic storage media bin. The magnetic field generator may include permanent magnets of varying intrinsic coercivities and/or remanences.

Abstract: A permanent magnet degausser includes at least one magnetic field generator comprising magnetic elements arranged near a media conveyance path and a conveyor for transporting magnetic media through a magnetic media conveyance path. A passive belt or protector plate may be provided to assist the passage of the magnetic media through the applied magnetic field. The conveyor may be a continuous motion conveyor belt including cleats for holding the magnetic media or a reciprocal media conveyor including magnetic storage media bin. The magnetic field generator may include permanent magnets of varying intrinsic coercivities and/or remanences.

Abstract: Disclosed herein, in certain embodiments, are peptides for use in inhibiting the interactions of PF4 and RANTES. Further disclosed herein, are methods for treating an inflammatory disease, disorder, condition, or symptom. In some embodiments, the method comprises co-administering an agent that inhibits the interactions of PF4 and RANTES and a second active agent.

Abstract: A magnetic field verifier apparatus includes a magnetic field detection element configured to produce a voltage signal in response to an applied magnetic field wherein the voltage signal corresponds to the strength of the applied magnetic field. A current source coupled to the magnetic field detection element provides a stimulating current for the magnetic field detection element that builds in a ramp-like progression. A microcontroller is in communication with the voltage signal wherein the microcontroller is configured to detect and control the ramping time of the magnetic field detection element and to sense after the ramping time the voltage signal from the magnetic field detection element. The magnetic field verifier apparatus is configurable to sense particular field strengths at various frequencies and store the readings to provide the user with a reliable verification that a particular magnetic field strength has been produced in a particular environment.

Abstract: One or more pairs of magnet assemblages (14 and 16) are provided with magnetized segments (21-30) arranged in a Halbach-like array. The magnet assemblages (14 and 16) define a gap (18) through which magnetic data storage media (12) pass in a direction (20) across the segments (21-30). The magnetized sides (36) of the magnet assemblages (14 and 16) face each other thereby creating strong magnetic fields which degauss the magnetic data storage media (12) passing through the gap (18).

Abstract: In an intervertebral implant with a top contacting element, a bottom contacting element and arranged between these a core which with an upper, spherical bearing surface engages a spherical bearing socket, having the same radius, of the top contacting element and with a lower, spherical bearing surface engages a spherical bearing socket, having the same radius, of the bottom contacting element, in order to improve the kinematics and the endurance, it is proposed that the radius of the bearing surface and of the bearing socket receiving it differ on opposing sides of the core at least by the factor 5.