Abstract: The present invention is directed to an improvement in a wire or cable system comprising a wire or cable portion, an insulation composition surrounding the wire or cable portion, a filler material surrounding the insulation composition and a jacket composition surrounding the filler material wherein either the insulation composition, the jacket composition, or both comprise at least one antioxidant, wherein the improvement comprises the inclusion in the filler material of a stabilizing mixture comprising at least two antioxidants, selected from at least two members of the group consisting of:(a) metal dithiocarbamate salts,(b) amine antioxidants, and(c) sterically hindered phenolic antioxidants,wherein the stabilizing mixture is present in the filler material in an amount that is effective for the reduction of the oxidation of the cable filling material, thereby reducing deterioration of the jacket and/or insulation.