Patents by Inventor Robert Scott Kuersten

Robert Scott Kuersten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF ISOTHERMAL COMPLEMENTARY DNA AND LIBRARY PREPARATION
    Publication number: 20240150753
    Abstract: Described herein are compositions and methods for preparing double-stranded complementary DNA (cDNA) from RNA. In some embodiments, these methods allow isothermal preparation of cDNA. In some embodiments, these methods allow mesophilic or thermostable preparation of cDNA. Also described herein are compositions and methods for preparing cDNA and a library of double-stranded cDNA fragments in a single reaction vessel.
    Type: Application
    Filed: September 27, 2023
    Publication date: May 9, 2024
    Applicant: Illumina, Inc.
    Inventors: Allison Yunghans, Angelica Marie Barr Schalembier, Kayla Busby, Stephen M. Gross, Robert Scott Kuersten, Frederick W. Hyde
  • Methods of Preparing Directional Tagmentation Sequencing Libraries Using Transposon-Based Technology with Unique Molecular Identifiers for Error Correction
    Publication number: 20240026348
    Abstract: Materials and methods for preparing nucleic acid libraries for next-generation sequencing are described herein. A variety of approaches are described relating to the use of unique molecular identifiers with transposon-based technology in the preparation of sequencing libraries. Also described herein are sequencing materials and methods for identifying and correcting amplification and sequencing errors.
    Type: Application
    Filed: September 28, 2023
    Publication date: January 25, 2024
    Applicants: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Susan C. Verity, Robert Scott Kuersten, Niall Anthony Gormley, Andrew B. Kennedy, Sarah E. Shultzaberger, Andrew Slatter, Emma Bell, Sebastien Georg Gabriel Ricoult, Grace DeSantis, Fiona Kaper, Han-Yu Chuang, Oliver Jon Miller, Jason Richard Betley, Stephen M. Gross, Mats Ekstrand
  • Preparation of RNA and DNA Sequencing Libraries Using Bead-Linked Transposomes
    Publication number: 20230183682
    Abstract: This application describes methods of preparing an immobilized library of tagged RNA fragments. Also described herein are a number of methods of preparing DNA and RNA sequencing libraries from a single sample. These methods can include library preparation from single cells.
    Type: Application
    Filed: February 2, 2023
    Publication date: June 15, 2023
    Applicants: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Niall Anthony Gormley, Andrew B. Kennedy, Robert Scott Kuersten, Gary Schroth, Carlo Randise-Hinchliff, Sarah E. Shultzaberger, Fiona Kaper, Yir-Shyuan Wu, Tarun Khurana, Foad Mashayekhi
  • Solid Supports and Methods for Depleting and/or Enriching Library Fragments Prepared from Biosamples
    Publication number: 20230094911
    Abstract: Described herein are solid supports and methods for depleting library fragments prepared from unwanted RNA sequences and/or enriching library fragments prepared from desired RNA sequences. These methods may incorporate microfluidics and flowcells for greater ease of use. Libraries enriched or depleted with the present methods may be used for sequencing. Also described are probes and methods for enzymatic depletion of ribosomal RNA from human microbiome samples.
    Type: Application
    Filed: September 30, 2022
    Publication date: March 30, 2023
    Applicant: ILLUMINA, INC.
    Inventors: Robert Scott Kuersten, Jeffrey Koble