Abstract: The present disclosure relates to a water drain arrangement for a body of a vehicle. The water drain arrangement includes a drain channel, a tubular feed-through device extending through a first opening of a first wall panel of the body and a second opening of a second wall panel of the body. The water drain arrangement includes a body shell-fixed sleeve extending through the first shell opening of the first wall panel and is coupled to the first wall panel in a fluid-tight manner. A first end of the feed-through device is inserted through a first end of the body shell-fixed sleeve and includes a drain extending through a second end of the feed-through device. A free end of the drain channel is held in a fluid-tight manner in a seat of the feed-through device, which is disposed at a second end of the feed-through device.

Abstract: The present disclosure relates to a water drain arrangement for a body of a vehicle. The water drain arrangement includes a drain channel, a tubular feed-through device extending through a first opening of a first wall panel of the body and a second opening of a second wall panel of the body. The water drain arrangement includes a body shell-fixed sleeve extending through the first shell opening of the first wall panel and is coupled to the first wall panel in a fluid-tight manner. A first end of the feed-through device is inserted through a first end of the body shell-fixed sleeve and includes a drain extending through a second end of the feed-through device. A free end of the drain channel is held in a fluid-tight manner in a seat of the feed-through device, which is disposed at a second end of the feed-through device.

Abstract: Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subclasses, and for predicting outcomes based on class or subclass. New therapeutic agents and methods for the treatment of cancer.

Abstract: Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subclasses, and for predicting outcomes based on class or subclass. New therapeutic agents and methods for the treatment of cancer.

Abstract: The present invention provides methods and reagents relating to establishing and using biomarker:chemical compound correlations. The invention provides correlated biomarker:compound pairs, and further provides methods of using such pairs, for example, in the identification of tumors or tumor cells likely to be responsive or resistant to particular therapy, and/or the identification of chemical compounds likely (or unlikely) to be useful in the treatment of particular tumors.

Abstract: Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subclasses, and for predicting outcomes based on class or subclass. New therapeutic agents and methods for the treatment of cancer.

Abstract: The thermal load to which a turbine is subjected is kept within an acceptable range by monitoring the change in temperature of the medium that is supplied to the turbine, especially fresh stream, over time. An emergency trip for the supply of fresh steam to the turbine preferably takes place if a maximum temperature gradient is exceeded.

Abstract: According to the invention, the thermal load to which a turbine (4) is subjected is kept within an acceptable range by monitoring the change in temperature (T) of the medium that is supplied to the turbine (4), especially fresh steam, over time. An emergency trip for the supply of fresh steam to the turbine (4) preferably takes place if a maximum temperature gradient (dT/dt(max)) is exceeded.