Patents by Inventor Robert Shapiro

Robert Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190154079
    Abstract: A hub for interconnecting a plurality struts at a node of geodesic framework features a receiver and a holding mechanism. The receiver has a plurality of receptacles to each receive an end of a respective strut. The holding mechanism is movable between a full-hold position and different partial-hold positions. The full-hold position at least partially obstructs each of the receptacles to block withdrawal of any strut ends already received in the receptacles. Each partial-hold position reveals one of the receptacles to enable insertion or withdrawal of a strut end, while continuing to obstruct all of the other receptacles to prevent inadvertent separation of any previously installed strut. Struts are inserted one-by-one as the holding mechanism is indexed from one partial-hold position to the next, without worry of any preceding strut separating from the hub. A kit with a spacer enables fastening of two hubs together in a multi-layer geodesic framework.
    Type: Application
    Filed: November 21, 2017
    Publication date: May 23, 2019
    Inventor: Robert Shapiro
  • Publication number: 20070032418
    Abstract: Lead compounds were obtained in a high throughput screen (HTS) of angiogenin (ANG; a potent inducer of angiogenesis) enzyme activity, an RNase. One lead was shown to delay appearance of tumors in an animal tumor system, and to reduce the number of animals having tumors. Several lead compound analogs were found to be even more potent inhibitors of ANG activity compared to the original leads, and two were also found to have greater affinity for ANG than for pancreatic RNase. Other embodiments disclose a method comprising obtaining a ribonuclease inhibitor and a composition; and admixing the ribonuclease inhibitor and the composition to form an admixture, wherein a ribonuclease that may be present in the admixture is inhibited.
    Type: Application
    Filed: February 25, 2004
    Publication date: February 8, 2007
    Applicant: Ambion, Inc
    Inventors: Robert Shapiro, Jeremy Jenkins, Richard Kao, Gary Latham
  • Patent number: 6230286
    Abstract: A mechanism is provided for a failed computer system to send a report of the failure to a remote site without dependency on a service processor or maintenance processor. The computer system is capable of reporting system failure to a remote site independent of whether the system may be successfully rebooted. The system includes a CPU, and, coupled to the CPU, a non-volatile control store, a main memory, a storage device storing a computer operating system, and a data modem. Firmware is resident in the non-volatile control store of the main computer system for reporting system failure to a remote site independent of whether the system may be successfully rebooted by reloading the operating system into main memory. The firmware is invoked upon occurrence of a non-recoverable error and provides for assembling failure-related information, establishing communication with the remote site, and transmitting the failure-related information to the remote site.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: May 8, 2001
    Assignee: Siemens Information and Communication Products LLC
    Inventors: Robert Shapiro, Paul Andrew Dorwin
  • Patent number: 5266687
    Abstract: An inhibitor of angiogenin and method of use of the inhibitor, wherein the inhibitor inhibits the angiogenic activity of angiogenin. The inhibitor is dispensed at a suitable concentration within a physiologically compatable medium, suitable for administration to an animal in sufficient quantity to inhibit the biological activity of naturally occurring angiogenin within the animal.
    Type: Grant
    Filed: May 16, 1991
    Date of Patent: November 30, 1993
    Assignee: The President and Fellows of Harvard College
    Inventors: Robert Shapiro, Bert L. Vallee
  • Patent number: 5019556
    Abstract: An inhibitor of angiogenin and method of use of the inhibitor, wherein the inhibitor inhibits the angiogenic activity of angiogenin. The inhibitor is dispensed at a suitable concentration within a physiologically compatable medium, suitable for administration to an animal in sufficient quantity to inhibit the biological activity of naturally occurring angiogenin within the animal.
    Type: Grant
    Filed: April 5, 1988
    Date of Patent: May 28, 1991
    Assignee: President and Fellows of Harvard College
    Inventors: Robert Shapiro, Bert L. Vallee
  • Patent number: 4966964
    Abstract: An inhibitor of angiogenin and method of use of the inhibitor, wherein the inhibitor inhibits the angiogenic activity of angiogenin. The inhibitor is dispensed at a suitable concentration within a physiologically compatable medium, suitable for administration to an animal in sufficient quantity to inhibit the biological activity of naturally occurring angiogenin within the animal.
    Type: Grant
    Filed: April 14, 1987
    Date of Patent: October 30, 1990
    Assignee: President and Fellows of Harvard College
    Inventors: Robert Shapiro, Bert L. Vallee