Abstract: Arrangements of the present disclosure relate to a system including a datacenter, having an electrical connection configured to receive electrical power generated from landfill gas, a thermal connection configured to receive thermal energy generated as a byproduct of generating the electrical power from the landfill gas, a datacenter load powered by the electrical power, and a cooling plant configured to cool the datacenter load using the thermal energy.

Abstract: A handgun sear has a sear body extending between a proximal end portion to a distal end portion. The sear defines a first engagement surface adjacent the proximal end portion and a second engagement surface positioned distally of the first engagement surface. The sear can pivot about the distal end portion between a cocked position and a displaced position. The second engagement surface can be used to arrest forward movement of the striker in the event of an impulse that causes the striker to disengage from the first engagement surface. The sear may be incorporated into a fire control assembly of a semiautomatic handgun or other firearm.

Abstract: A handgun sear has a sear body extending between a proximal end portion to a distal end portion. The sear defines a first engagement surface adjacent the proximal end portion and a second engagement surface positioned distally of the first engagement surface. The sear can pivot about the distal end portion between a cocked position and a displaced position. The second engagement surface can be used to arrest forward movement of the striker in the event of an impulse that causes the striker to disengage from the first engagement surface. The sear may be incorporated into a fire control assembly of a semiautomatic handgun or other firearm.

Abstract: Arrangements of the present disclosure relate to a system including a datacenter, having an electrical connection configured to receive electrical power generated from landfill gas, a thermal connection configured to receive thermal energy generated as a byproduct of generating the electrical power from the landfill gas, a datacenter load powered by the electrical power, and a cooling plant configured to cool the datacenter load using the thermal energy.

Abstract: The invention relates to niclosamide and derivates thereof, which effectively inhibit transcription of the S100A4 gene, resulting in inhibition and/or reduction of S100A4-induced cell motility, invasiveness, metastasis and proliferation of human cancer cells.

Abstract: Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.

Abstract: Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.

Abstract: The invention provides methods and pharmaceutical compositions for inhibiting viral replication, particularly retroviral replication. The methods comprise administration of stibonic acid or diphenyl compounds that disrupt viral nucleocapsid binding to nucleic acids.

Abstract: This invention relates to a card edge connector, multiple numbers of which are arranged in banks and interconnected by discrete wires. The present invention provides a system for lacing wires through passageways and channels, thereby aligning the wires for insertion within slotted plate electrical contacts. One or a pair of wires may be inserted in each contact. Wire gripping strain relief is provided in each of the wire aligning passageways. The passageways and channels position the wire in an orderly arrangement in different planes within the connectors. Wire retention gates prevent removal of the wires from the channels and passageways.