Patents by Inventor Robert Shoemaker

Robert Shoemaker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NICLOSAMIDE FOR THE TREATMENT OF CANCER METASTASIS
    Publication number: 20140294957
    Abstract: The invention relates to niclosamide and derivates thereof, which effectively inhibit transcription of the S100A4 gene, resulting in inhibition and/or reduction of S100A4-induced cell motility, invasiveness, metastasis and proliferation of human cancer cells.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 2, 2014
    Applicant: MAXDELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN
    Inventors: Ulrike Stein, Wolfgang Walther, Ulrike Sack, Robert Shoemaker, Dominic Scudiero, Peter M Schlag
  • Kinase inhibitors, compositions thereof, and methods of use therewith
    Patent number: 8765802
    Abstract: Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: July 1, 2014
    Assignees: Provid Pharmaceuticals, Inc., United States of America as represented by the Department of Health and Human Resources NIH
    Inventors: Robert Shoemaker, John Cardellina, Michael Currens, Sudhir Kondapaka, Yves Pommier, Andy Jobson, Dominic Scudiero, David Waugh, George Lountos, Guangtao Zhang, Andrew Colasanti, Christopher R. Self, Janet Cicariello Cook
  • KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH
    Publication number: 20090018141
    Abstract: Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
    Type: Application
    Filed: June 9, 2008
    Publication date: January 15, 2009
    Inventors: Robert Shoemaker, John Cardellina, Michael Currens, Sudhir Kondapaka, Yves Pommier, Andy Jobson, Dominic Scudiero, David Waugh, George Lountos, Charles M. Cook, Guangtao Zhang, Andrew Colasanti, Christopher R. Self, Janet Cicariello Cook
  • Identification of anti-hiv compounds inhibiting virus assembly and binding of nucleocapsid protein to nucleic acid
    Publication number: 20060263772
    Abstract: The invention provides methods and pharmaceutical compositions for inhibiting viral replication, particularly retroviral replication. The methods comprise administration of stibonic acid or diphenyl compounds that disrupt viral nucleocapsid binding to nucleic acids.
    Type: Application
    Filed: October 8, 2003
    Publication date: November 23, 2006
    Applicant: The Government of the USA as Represented by the Secretary of the Dept. of Health and Human Service
    Inventors: Robert Shoemaker, Michael Currens, Alan Rein, Ya-Xiong Feng, Robert Fisher, Andrew Stephen, Karen Worthy, Shizuko Sei, Bruce Crise, Louis Henderson