Abstract: This disclosure discloses various dispensation devices for dispensation of various volumes of content. For example, some of such content can include cream.

Abstract: The present disclosure provides prodrug compounds of MDMA, MDA, and derivatives thereof having an improved pharmacokinetic profile suitable for the treatment of various neurological diseases.

Abstract: A pressure screen for use in a fiber web product process (10) has an inlet zone (12), a basket having an accept zone (14) and a reject zone (20). The pressure screen (10) has a housing (28) inside which a rotor (27) is located. The reject zone (20) of the pressure screen (10) has a cover (22) forming a rejects chamber (21) for the reject zone (20). The cover (22) of the rejects chamber (21) of the screen (10) is removable by a reopenable attachment means (25, 29) attached to the housing (28) of the screen (10).

Abstract: An accessory is provided for a disc refiner that is for refining lignocellulosic material and includes at least two refiner discs, at least one of which is a rotor refiner disc, a motor, and a rotation shaft assembly that includes (i) a rotation shaft, (ii) a shaft housing, (iii) at least one bearing between the shaft housing and the rotation shaft for allowing rotation of the rotation shaft within the shaft housing, and (iv) at least one ring-shaped locknut that encircles the rotation shaft, is configured for holding the at least one bearing in place on the rotation shaft, and includes notches for a tool to grip when attaching the locknut in the rotation shaft assembly. The accessory is configured to be attached to the locknut and includes at least one covering part configured to at least partly cover the notches of the locknut when attached to the locknut.

Abstract: A method for updating a disc refiner by at least partly covering notches of a locknut in the disc refiner and an accessory for a disc refiner Said disc refiner comprising a motor and a rotation shaft assembly, wherein said rotation shaft assembly comprises a rotation shaft, which is connecting the motor and a rotor refiner disc of the disc refiner for driving rotation of the rotor refiner disc from the motor, said rotation shaft assembly further comprising at least one bearing, which is provided between a shaft housing and the rotation shaft for allowing rotation of the rotation shaft within the shaft housing, said rotation shaft assembly further comprising at least one ring-shaped locknut, which is encircling the rotation shaft and configured for holding the at least one bearing in place on the rotation shaft, said locknut comprising notches for a tool to grip when attaching the locknut in the rotation shaft assembly, wherein said accessory is configured for being attached to the locknut and comprises at lea

Abstract: A pressure screen for use in a fiber web product process (10) has an inlet zone (12), a basket having an accept zone (14) and a reject zone (20). The pressure screen (10) has a housing (28) inside which a rotor (27) is located. The reject zone (20) of the pressure screen (10) has a cover (22) forming a rejects chamber (21) for the reject zone (20). The cover (22) of the rejects chamber (21) of the screen (10) is removable by a reopenable attachment means (25, 29) attached to the housing (28) of the screen (10).

Abstract: A method for updating a disc refiner by at least partly covering notches of a locknut in the disc refiner and an accessory for a disc refiner Said disc refiner comprising a motor and a rotation shaft assembly, wherein said rotation shaft assembly comprises a rotation shaft, which is connecting the motor and a rotor refiner disc of the disc refiner for driving rotation of the rotor refiner disc from the motor, said rotation shaft assembly further comprising at least one bearing, which is provided between a shaft housing and the rotation shaft for allowing rotation of the rotation shaft within the shaft housing, said rotation shaft assembly further comprising at least one ring-shaped locknut, which is encircling the rotation shaft and configured for holding the at least one bearing in place on the rotation shaft, said locknut comprising notches for a tool to grip when attaching the locknut in the rotation shaft assembly, wherein said accessory is configured for being attached to the locknut and comprises at lea

Abstract: A hub and a member, the member having a central opening. The hub is received in the member central opening. The hub has a center, and a hub axis through the center. The hub also has a splined exterior with a plurality of splines, each spline having a spline surface, and the member central opening has internal splines that engage with the hub splined exterior. At least one of the hub splines has a wear indicator, the wear indicator comprising a surface mark that extends along a portion of the spline surface in the same direction as the hub axis.

Abstract: A hub and a member, the member having a central opening. The hub is received in the member central opening. The hub has a center, and a hub axis through the center. The hub also has a splined exterior with a plurality of splines, each spline having a spline surface, and the member central opening has internal splines that engage with the hub splined exterior. At least one of the hub splines has a wear indicator, the wear indicator comprising a surface mark that extends along a portion of the spline surface in the same direction as the hub axis.

Abstract: A sharp extractor has a ram that is actuatable to move from a disengaged position to an engaged position to dislodge a sharp from a medical device, and then return back to the disengaged position. With the medical device secured in axial alignment with the ram, the actuator is actuated to move to its engaged position, whereupon the sharp is detached from the medical device. The dislodged sharp is channeled directly into a medical waste container. Upon removing the sharp from the medical device, the medical device can be treated as standard medical waste, thereby reducing the cost associated with disposal of the medical device. With the volume of the sharp being greatly reduced as a result of removal from the relatively bulky medical device, the frequency of having to dispose the sharps can be greatly reduced, thereby further reducing cost associated with the disposal of the sharps.

Abstract: A sharp extractor has a ram that is actuatable to move from a disengaged position to an engaged position to dislodge a sharp from a medical device, and then return back to the disengaged position. With the medical device secured in axial alignment with the ram, the actuator is actuated to move to its engaged position, whereupon the sharp is detached from the medical device. The dislodged sharp is channeled directly into a medical waste container. Upon removing the sharp from the medical device, the medical device can be treated as standard medical waste, thereby reducing the cost associated with disposal of the medical device. With the volume of the sharp being greatly reduced as a result of removal from the relatively bulky medical device, the frequency of having to dispose the sharps can be greatly reduced, thereby further reducing cost associated with the disposal of the sharps.

Abstract: In one embodiment of the invention, there is provided a method of selecting a surface chemistry for culturing a given cell line, including the steps of: (i) providing a first substrate having a plasma polymerized surface with first and second regions, said first region having a first concentration of carboxylic acid groups on said plasma polymerized surface and said second region having a second concentration of carboxylic acid groups on said plasma polymerized surface, wherein said first and second concentrations are different; (ii) culturing cells from said cell line on said plasma polymerized surface in each said region; (iii) observing activity of said cultured cells in each said region, said activity selected from the group consisting of alkaline phosphatase activity of the cultured cells, cell growth of the cultured cells, attachment of the cultured cells, and cell spreading of the cultured cells; and iv) selecting, based on a particular observed activity, a secondary substrate for culturing said cells

Abstract: Embodiments of the inventive technology may provide a leaked fluid detection and response system in one aspect, and in another aspect, an environmental enclosure for at least a component of such leaked fluid detection system. Various embodiments of the leaked fluid detection and response system may provide wireless communication of detected leaks and a PLC that automates response and provides information regarding the presence of a leak. Enclosures may, in various embodiments, comprehensively surround enclosed components, thermally insulate enclosed components, include a leaked fluid capture basin, be aerodynamically streamlined, and/or be vermin-tight.

Abstract: In one embodiment of the invention, there is provided a method of selecting a surface chemistry for culturing a given cell line, including the steps of: (i) providing a first substrate having a plasma polymerized surface with first and second regions, said first region having a first concentration of carboxylic acid groups on said plasma polymerized surface and said second region having a second concentration of carboxylic acid groups on said plasma polymerized surface, wherein said first and second concentrations are different; (ii) culturing cells from said cell line on said plasma polymerized surface in each said region; (iii) observing activity of said cultured cells in each said region, said activity selected from the group consisting of alkaline phosphatase activity of the cultured cells, cell growth of the cultured cells, attachment of the cultured cells, and cell spreading of the cultured cells; and iv) selecting, based on a particular observed activity, a secondary substrate for culturing said cells

Abstract: Embodiments of the inventive technology may provide a leaked fluid detection and response system in one aspect, and in another aspect, an environmental enclosure for at least a component of such leaked fluid detection system. Various embodiments of the leaked fluid detection and response system may provide wireless communication of detected leaks and a PLC that automates response and provides information regarding the presence of a leak. Enclosures may, in various embodiments, comprehensively surround enclosed components, thermally insulate enclosed components, include a leaked fluid capture basin, be aerodynamically streamlined, and/or be vermin-tight.

Abstract: A secure domain name service for a computer network is disclosed that includes a portal connected to a computer network, such as the Internet, and a domain name database connected to the computer network through the portal. The portal authenticates a query for a secure computer network address, and the domain name database stores secure computer network addresses for the computer network. Each secure computer network address is based on a non-standard top-level domain name, such as .scom, .sorg, .snet, .snet, .sedu, .smil and .sint.

Abstract: A plurality of computer nodes communicate using seemingly random Internet Protocol source and destination addresses. Data packets matching criteria defined by a moving window of valid addresses are accepted for further processing, while those that do not meet the criteria are quickly rejected. Improvements to the basic design include (1) a load balancer that distributes packets across different transmission paths according to transmission path quality; (2) a DNS proxy server that transparently creates a virtual private network in response to a domain name inquiry; (3) a large-to-small link bandwidth management feature that prevents denial-of-service attacks at system chokepoints; (4) a traffic limiter that regulates incoming packets by limiting the rate at which a transmitter can be synchronized with a receiver; and (5) a signaling synchronizer that allows a large number of nodes to communicate with a central node by partitioning the communication function between two separate entities.

Abstract: In one embodiment of the invention, there is provided a kit including: (i) a plasma polymerized surface having first and second regions, said first region including a first concentration of carboxylic acid groups on said plasma polymerized surface and said second region including a second concentration of carboxylic acid groups on said plasma polymerized surface, wherein said first concentration and said second concentration are different; (ii) a first plasma polymerized secondary substrate having carboxylic acid groups disposed consistently thereacross at a concentration equal to said first concentration; and, (iii) a second plasma polymerized secondary substrate having carboxylic acid groups disposed consistently thereacross at a concentration equal to said second concentration.

Abstract: Embodiments of the inventive technology may provide a leaked fluid detection and response system in one aspect, and in another aspect, an environmental enclosure for at least a component of such leaked fluid detection system. Various embodiments of the leaked fluid detection and response system may provide wireless communication of detected leaks and a PLC that automates response and provides information regarding the presence of a leak. Enclosures may, in various embodiments, comprehensively surround enclosed components, thermally insulate enclosed components, include a leaked fluid capture basin, be aerodynamically streamlined, and/or be vermin-tight.

Abstract: In one embodiment of the invention, there is provided a kit including: (i) a plasma polymerized surface having first and second regions, said first region including a first concentration of carboxylic acid groups on said plasma polymerized surface and said second region including a second concentration of carboxylic acid groups on said plasma polymerized surface, wherein said first concentration and said second concentration are different; (ii) a first plasma polymerized secondary substrate having carboxylic acid groups disposed consistently thereacross at a concentration equal to said first concentration; and, (iii) a second plasma polymerized secondary substrate having carboxylic acid groups disposed consistently thereacross at a concentration equal to said second concentration.