Patents by Inventor Robert Singhaus

Robert Singhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic amides as kinase inhibitors
    Patent number: 10940154
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 9, 2021
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • Heterocyclic amides as kinase inhibitors
    Patent number: 10933070
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: March 2, 2021
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • HETEROCYCLIC AMIDES AS KINASE INHIBITORS
    Publication number: 20190262356
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 29, 2019
    Inventors: Jae U. JEONG, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, JR., Daohua Zhang
  • HETEROCYCLIC AMIDES AS KINASE INHIBITORS
    Publication number: 20190201413
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 4, 2019
    Inventors: Jae U. JEONG, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, JR., Daohua Zhang
  • Heterocyclic amides as kinase inhibitors
    Patent number: 10292987
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 21, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • HETEROCYCLIC AMIDES AS KINASE INHIBITORS
    Publication number: 20170008878
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: September 21, 2016
    Publication date: January 12, 2017
    Inventors: Deepak BANDYOPADHYAY, Patrick M. EIDAM, Peter J. GOUGH, Philip Anthony HARRIS, Jae U. JEONG, Jianxing KANG, Bryan Wayne KING, Ami LAKDAWALA SHAH, Lara Kathryn LEISTER, Robert W. MARQUIS, JR., Attiq RAHMAN, Joshi M. RAMANJULU, Clark A. SEHON, Robert SINGHAUS, JR., Daohua ZHANG
  • Amino-quinolines as kinase inhibitors
    Patent number: 9216965
    Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: December 22, 2015
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Linda N. Casillas, Michael P. Demartino, Pamela A. Haile, John F. Mehlmann, Joshi M. Ramanjulu, Robert Singhaus, Jr.
  • HETEROCYCLIC AMIDES AS KINASE INHIBITORS
    Publication number: 20150353533
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A, L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 10, 2015
    Inventors: Deepak BANDYOPADHYAY, Patrick M. EIDAM, Peter J. GOUGH, Philip Anthony HARRIS, Jae U. JEONG, Jianxing KANG, Bryan Wayne KING, Ami LAKDAWALA SHAH, Lara Kathryn LEISTER, Robert W. MARQUIS, JR., Attiq RAHMAN, Joshi M. RAMANJULU, Clark A. SEHON, Robert SINGHAUS, JR., Daohua ZHANG
  • AMINO-QUINOLINES AS KINASE INHIBITORS
    Publication number: 20150094333
    Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: September 13, 2013
    Publication date: April 2, 2015
    Inventors: Linda N. Casillas, Michael P. Demartino, Pamela A. Haile, John F. Mehlmann, Joshi M. Ramanjulu, Robert Singhaus, JR.
  • NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS
    Publication number: 20120010205
    Abstract: Disclosed are quinoline esters of Formula (I): which are useful as Liver X receptors (LXR) modulators. Pharmaceutical compositions containing quinoline esters of Formula (I) and the use of quinoline esters of Formula (I) in the safe treatment of various skin disorders are also disclosed. Methods for preparing and using quinoline esters are further described.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 12, 2012
    Applicant: Wyeth LLC
    Inventors: Ronald Charles Bernotas, Robert Singhaus, Sunil Nagpal, Catherine Thompson
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20060074128
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure wherein R, R?, A, A?, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 6, 2006
    Applicant: Wyeth
    Inventors: Christopher Miller, Michael Collini, David Kaufman, Robert Morris, Robert Singhaus, John Ullrich, Heather Harris, James Keith, Leo Albert, Rayomand Unwalla
  • Tetracyclic compounds as estrogen ligands
    Publication number: 20060004087
    Abstract: This invention provides estrogen receptor modulators having the structure: wherein R1, R2, R3, R4, Q, n, R8, R9, R10, and R11 have been defined in the specification; or a pharmaceutically acceptable salt thereof. The invention further provides methods for the preparation and use of the compounds.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 5, 2006
    Applicant: Wyeth
    Inventors: Christopher Miller, Michael Collini, Robert Morris, Robert Singhaus
  • Quinolines useful in treating cardiovascular disease
    Publication number: 20050131014
    Abstract: This invention provides compounds of formula I that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Application
    Filed: December 10, 2004
    Publication date: June 16, 2005
    Applicant: Wyeth
    Inventors: Michael Collini, Robert Singhaus, Baihua Hu, James Jetter, Robert Morris, David Kaufman, Christopher Miller, John Ullrich, Rayomand Unwalla, Jay Wrobel, Elaine Quinet, Ponnal Nambi, Ronald Bernotas, Merle Elloso
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20050038107
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R?, A, A?, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 21, 2004
    Publication date: February 17, 2005
    Inventors: Christopher Miller, Michael Collini, David Kaufman, Robert Morris, Robert Singhaus, John Ullrich, Heather Harris, James Keith, Leo Albert, Rayomand Unwalla