Patents by Inventor Robert Sitrin

Robert Sitrin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant hepatitis B surface antigen
    Patent number: 7098309
    Abstract: The present invention provides an improved rHBsAg that exhibits a higher antigenicity and immunogenicity than that previously known in the art. A method of making the improved rHBsAg is also provided. The improved HBsAg is used to provide vaccines with lower amounts of active ingredient, vaccines with higher immunogenicity and combination vaccines which produce and protective immunization against infection by hepatitis B virus and other infectious agents.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: August 29, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Qinjian Zhao, Robert Sitrin, Dicky G. Abraham, David P. Gervais, Juan Gimenez
  • Recombinant hepatitis B surface antigen
    Publication number: 20060149032
    Abstract: The present invention provides an improved rHBsAg that exhibits a higher antigenicity and immunogenicity than that previously known in the art. A method of making the improved rHBsAg is also provided. The improved HBsAg is used to provide vaccines with lower amounts of active ingredient, vaccines with higher immunogenicity and combination vaccines which produce and protective immunization against infection by hepatitis B virus and other infectious agents.
    Type: Application
    Filed: January 27, 2006
    Publication date: July 6, 2006
    Inventors: Qinjian Zhao, Robert Sitrin, Dicky Abraham
  • RECOMBINANT HEPATITIS B SURFACE ANTIGEN
    Publication number: 20030113342
    Abstract: The present invention provides an improved rHBsAg that exhibits a higher antigenicity and immunogenicity than that previously known in the art. A method of making the improved rHBsAg is also provided. The improved HBsAg is used to provide vaccines with lower amounts of active ingredient, vaccines with higher immunogenicity and combination vaccines which produce and protective immunization against infection by hepatitis B virus and other infectious agents.
    Type: Application
    Filed: December 22, 1999
    Publication date: June 19, 2003
    Inventors: QINJIAN ZHAO, ROBERT SITRIN, DICKY G. ABRAHAM, DAVID P. GERVAIS, JUAN GIMENEZ