Patents by Inventor Robert Smakman

Robert Smakman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11942302
    Abstract: Apparatuses and methods for charged-particle detection may include a deflector system configured to direct charged-particle pulses, a detector having a detection element configured to detect the charged-particle pulses, and a controller having a circuitry configured to control the deflector system to direct a first and second charged-particle pulses to the detection element; obtain first and second timestamps associated with when the first charged-particle pulse is directed by the deflector system and detected by the detection element, respectively, and third and fourth timestamps associated with when the second charged-particle pulse is directed by the deflector system and detected by the detection element, respectively; and identify a first and second exiting beams based on the first and second timestamps, and the third and fourth timestamps, respectively.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: March 26, 2024
    Assignee: ASML Netherlands B.V.
    Inventors: Arno Jan Bleeker, Pieter Willem Herman De Jager, Maikel Robert Goosen, Erwin Paul Smakman, Albertus Victor Gerardus Mangnus, Yan Ren, Adam Lassise
  • Publication number: 20230201799
    Abstract: The present invention relates to a method for preparing a macromolecular composition comprising indene-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolecular compositions. The macromolecular compositions are useful for undergoing subsequent reactions with small molecules.
    Type: Application
    Filed: February 10, 2023
    Publication date: June 29, 2023
    Applicants: Stichting voor de Technische Wetenschappen, Universiteit Utrecht Holding B.V., UMC Utrecht Holding B.V.
    Inventors: Robert Smakman, Wilhelmus Everhardus Hennink, Karin Gerarda Frederika Gerritsen, Jacobus Adrianus Wilhelmus Jong, Cornelus Franciscus van Nostrum
  • Patent number: 11612877
    Abstract: The present invention relates to a method for preparing a macromolecular composition comprising indene-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolecular compositions. The macromolecular compositions are useful for undergoing subsequent reactions with small molecules.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: March 28, 2023
    Assignees: Stichting voor de Technische Wetenschappen, Universiteit Utrecht Holding B.V., UMC Utrecht Holding B.V.
    Inventors: Robert Smakman, Wilhelmus Everhardus Hennink, Karin Gerarda Frederika Gerritsen, Jacobus Adrianus Wilhelmus Jong, Cornelus Franciscus van Nostrum
  • Publication number: 20230046628
    Abstract: The present invention relates to a method for preparing a macromolecular composition comprising phenylglyoxaldehyde-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolecular compositions. The macromolecular compositions are useful for undergoing subsequent reactions with small molecules, for instance to remove such small molecules from a solution.
    Type: Application
    Filed: November 20, 2020
    Publication date: February 16, 2023
    Applicants: Stichting voor de Technische Wetenschappen, Universiteit Utrecht Holding B.V., UMC Utrecht Holding B.V.
    Inventors: Robert Smakman, Wilhelmus Everhardus Hennink, Karin Gerarda Frederika Gerritsen, Jacobus Adrianus Wilhelmus Jong, Cornelus Franciscus van Nostrum
  • Publication number: 20220401889
    Abstract: The present invention relates to a method for preparing a membrane comprising sorbent particles that bind urea. The invention also relates to the sorbent-comprising membranes per se, and to methods of using the membranes. The membranes are useful for undergoing subsequent reactions with small molecules such as urea, for instance to remove urea from a solution.
    Type: Application
    Filed: November 20, 2020
    Publication date: December 22, 2022
    Applicants: Stichting voor de Technische Wetenschappen, UMC Utrecht Holding B.V., Universiteit Utrecht Holding B.V., Universiteit Twente
    Inventors: Dimitrios Stamatialis, Ilaria Geremia, Cornelus Franciscus van Nostrum, Karin Gerarda Frederika Gerritsen, Robert Smakman, Wilhelmus Everhardus Hennink, Jacobus Adrianus Wilhelmus Jong, Yong Guo
  • Publication number: 20200368721
    Abstract: The present invention relates to a method for preparing a macromolecular composition comprising indene-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolecular compositions. The macromolecular compositions are useful for undergoing subsequent reactions with small molecules.
    Type: Application
    Filed: December 4, 2018
    Publication date: November 26, 2020
    Applicants: Stichting voor de Technische Wetenschappen, Universiteit Utrecht Holding B.V., UMC Utrecht Holding B.V.
    Inventors: Robert Smakman, Wilhelmus Everhardus Hennink, Karin Gerarda Frederika Gerritsen, Jacobus Adrianus Wilhelmus Jong, Cornelus Franciscus van Nostrum
  • Publication number: 20090223899
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Application
    Filed: May 13, 2009
    Publication date: September 10, 2009
    Applicants: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Publication number: 20090218290
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Application
    Filed: May 13, 2009
    Publication date: September 3, 2009
    Applicants: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Patent number: 7544737
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: June 9, 2009
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Publication number: 20050131141
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 16, 2005
    Inventors: Mitchell Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Patent number: 6861473
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: March 1, 2005
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Publication number: 20040171754
    Abstract: Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
    Type: Application
    Filed: February 28, 2003
    Publication date: September 2, 2004
    Inventors: Mitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
  • Patent number: 6379294
    Abstract: A process for preparing an esterquat composition comprising (a) reacting a tertiary amine according to formula I: wherein R1 represents a C3-C6 hydrocarbon group, R2 represents a C3-C6 hydrocarbon group, a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a C3-C6 hydrocarbon group, R3 represents a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a —R4—OH group, R3 represents a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a —CH2[CH(OH)]nCH2OR5 group, R3 represents a —CH2[CH(OH)]nCH2OR5 group, R4 represents a C2-C4 hydrocarbon group, n is 1-4, and R5 represents H or a C1-C30 hydrocarbon group, with a C3-C6 hydrocarbyl halide or a di(C3-C6) hydrocarbyl sulfate, followed by (b) reaction with a C8-C30 acid halide, with the proviso that at least one hydroxy group is esterified.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: April 30, 2002
    Assignee: Akzo Nobel N.V.
    Inventors: Adrianus Buijs, Gerardus Van Gurp, Tjitte Nauta, Robert Smakman, Anne Marijke Wit-Van Grootheest
  • Patent number: 4897200
    Abstract: A carbonyl groups containing macromolecular material which is suitable for use as a sorbent for ammonia, urea or amino compounds. It contains structural units having 3 or more, optionally hydrated vicinal carbonyl groups, preferably keto groups, the C-atoms of which may form part of a ring structure. Particularly, the ring structure contains 5-7 C-atoms, and at least 2 ring atoms may form part of an aromatic ring system. The starting material used may be made of a polymer of the same type as that used in the manufacture of ion exchange resins. The carbonyl group containing unit may form part of an independent compound, e.g., ninhydrin which may be physically bonded to the macromolecular material, but is preferably covalently bonded thereto.
    Type: Grant
    Filed: November 10, 1986
    Date of Patent: January 30, 1990
    Assignee: Organon Teknika bv
    Inventor: Robert Smakman
  • Patent number: 4542015
    Abstract: An apparatus for purifying blood has a blood compartment and a clearance compartment separated by a semi-permeable membrane. The apparatus includes a device containing a cation exchange resin charged with metal ions whose phosphates are insoluble in water. Metal salts of iron, aluminum, zirconium, lanthanum, thorium and tin are deposited on a cation exchange material and the charged cation exchange resin is contacted with dialysis liquid. The process of treating blood with the dialysis liquid is also contemplated.
    Type: Grant
    Filed: August 19, 1982
    Date of Patent: September 17, 1985
    Assignee: Organon Teknika B.V.
    Inventors: Robert Smakman, Gerrit H. van den Berg
  • Patent number: 4213859
    Abstract: An apparatus for purifying blood has a blood compartment and a clearance compartment separated by a semi-permeable membrane. The apparatus includes a device containing a cation exchange resin charged with metal ions whose phosphates are insoluble in water. Metal salts of iron, aluminium, zirconium, lanthanum, thorium and tin are deposited on a cation exchange material and the charged cation exchange resin is contacted with dialysis liquid. The process of treating blood with the dialysis liquid is also contemplated.
    Type: Grant
    Filed: April 10, 1978
    Date of Patent: July 22, 1980
    Assignee: Akzo N.V.
    Inventors: Robert Smakman, Gerrit H. van den Berg
  • Patent number: 4177140
    Abstract: A method for removing a weak acid from an aqueous solution containing said acid is disclosed. The method comprises contacting said aqueous solution with an anion exchanger containing both strongly basic and weakly basic groups, said exchanger having a matrix comprising a copolymer of styrene and not more than about 20%, by weight, of a cross-linking agent, from about 3% to about 90% of the total basic groups being strongly basic groups of the quaternary ammonium type having the structure --CH.sub.2 N.sup.+ R.sub.1 R.sub.2 R.sub.3, wherein R.sub.1, R.sub.2, and R.sub.3 are independently selected from the group consisting of --CH.sub.3, --C.sub.2 H.sub.5, and --C.sub.2 H.sub.4 OH, and the balance of the basic groups being weakly basic groups of the tertiary amine type.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: December 4, 1979
    Assignee: Akzona Inc.
    Inventor: Robert Smakman
  • Patent number: 4160675
    Abstract: A process for removing an organic impurity from an aqueous solution is disclosed, said process comprising contacting the aqueous solution with an acid cation exchanger and subsequently with a polymer or polycondensate, which contains sulfur in the form of thiol groups bonded to carbon atoms.
    Type: Grant
    Filed: September 12, 1977
    Date of Patent: July 10, 1979
    Assignee: Akzona Incorporated
    Inventors: Wilhelmus Pannekeet, Robert Smakman
  • Patent number: 4157298
    Abstract: Ferric ions are removed from a concentrated aqueous zinc solution having a pH value in the range of about 0 to about 1.3, by contacting the zinc solution with a cation exchange chelate resin containing aminocarboxylic acid and/or iminodicarboxylic acid groups.
    Type: Grant
    Filed: December 23, 1977
    Date of Patent: June 5, 1979
    Assignee: Akzona Incorporated
    Inventors: Gerrit H. van den Berg, Wilhelmus Pannekeet, Kees Koerts, Robert Smakman