Abstract: This invention relates to the direct delivery of a vitamin composition to the large intestine, in order to decrease the growth of pathogenic organisms in the gut, such as Adherent Invasive E. coli (AIEC), Salmonella enteriditis and Clostridium difficile. The vitamin composition comprises a combination of the following vitamins: Vitamin C, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6 and folic acid.

Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Abstract: This invention relates to the direct delivery to the intestine of a vitamin composition to restore a balanced population and metabolic profile of gut microbiome bacteria which has been disrupted due to exposure to antibiotics. The vitamin composition may comprise Vitamin C as a sole active agent; Vitamin C in combination with Vitamin B2 and/or B3; or Vitamin C in combination with Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6 and Vitamin B9.

Abstract: The population of Dialister spp. bacteria in the gut microbiome is lower in people with various diseases. We have found that administration of vitamins/vitamin combinations such as: beta-carotene, Vitamin A, Vitamin D, Vitamin B5, Vitamin B2, a combination of Vitamin B2 and Vitamin C, Vitamin K, DHA, or EPA, when administered directly to the large intestine, so that it provides nourishment to the gut microbiome directly, can result in an increase of Dialister spp.

Abstract: The population of Coprococcus spp. bacteria in the gut microbiome is lower in people with various diseases. We have found that administration of vitamins / vitamin combinations such as : the combination of Vitamin B2 and C; Vitamin D3; beta-carotene, and Vitamin B5, when administered directly to the gut, so that it provides nourishment to the gut microbiome directly, can result in an increase of Coprococcus spp.

Abstract: This invention is directed to the use of a combination of antioxidants which are delivered to the gut microbiome. The antioxidants are riboflavin, beta-carotene, Vitamin C and Vitamin E. We have found that they deliver a degree of improvement to gut health comparable to known prebiotics, such as soluble fibers.

Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Abstract: Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, ?-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

Abstract: The present invention relates to a new delivery system for fat-soluble vitamins.

Abstract: The present invention relates to a new delivery system for specific water-soluble vitamins.

Abstract: The present invention relates to a new delivery system for PUFAs.

Abstract: The present invention relates to pharmaceutical combinations of at least one TNF inhibitor and riboflavin to treat patients suffering from inflammatory bowel disease (IBD) or other inflammatory conditions (such as rheumatoid arthritis, ankylosing spondylitis, psoriasis, lupus erythematous and multiple sclerosis). This invention also relates to additive and/or combinations of at least one TNF inhibitor and riboflavin. This invention is also related to a method for the treatment or prophylaxis of IBD, which method comprises administering a therapeutically effective amount of TNF inhibitor and riboflavin.

Abstract: The present invention relates to pharmaceutical combinations of at least one thiopurine and/or at least a pharmaceutically acceptable salt and/or at least one prodrug thereof and riboflavin to treat patients suffering from inflammatory bowel disease (IBD) or other inflammatory conditions. This invention also relates to additive and/or combinations of at least one thiopurine and riboflavin. This invention is also related to a method for the treatment or prophylaxis of IBD or other inflammatory conditions, which method comprises administering a therapeutically effective amount of thiopurine and riboflavin.

Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Abstract: Protective suits are used to protect the wearer against hazardous materials such as chemicals, pathogens, radioactive particles, electromagnetism, physical trauma and for rain protection. They are used to protect the wearer's surrounding in cleanrooms. Medical protective suits are used to prevent the spread of pathogens from the wearer. Unfortunately, they can cause heat stress by reducing air circulation. This invention discloses a protective suit with a breathing mask and dual one-way valves to draw air through the suit's interior using the forces generated by the wearer's breathing. Filters can be placed in the suit, or the suit can be made of a filter material to protect the wearer and the surroundings. The disclosed suit is lighter, less expensive to produce and more mobile than prior-art protective suit designs that use powered or externally supplied ventilation and cooling devices.

Abstract: Protective suits are used to protect the wearer against hazardous materials such as particulates, liquids, chemicals, pathogens, radiation, electromagnetism, physical trauma, heat and for rain protection. They are used to protect the wearer's surrounding in cleanrooms. Medical protective suits are used to prevent the spread of pathogens from the wearer. Unfortunately, they can cause heat stress by reducing air circulation. This invention discloses a protective suit with bellows and dual one-way valves operated by the normal movement of the wearer to draw air through the suit's interior. Filters can be placed in the suit, or the suit can be made of a filter material to protect the wearer and the surroundings. The disclosed suit is lighter, less expensive to produce and more mobile than prior-art protective suit designs that use powered or externally supplied ventilation and cooling devices.

Abstract: Protective suits are used to protect the wearer against hazardous materials such as particulates, liquids, chemicals, pathogens, radiation, electromagnetism, physical trauma, heat and for rain protection. They are used to protect the wearer's surrounding in cleanrooms. Medical protective suits are used to prevent the spread of pathogens from the wearer. Unfortunately, they can cause heat stress by reducing air circulation. This invention discloses a protective suit with bellows and dual one-way valves operated by the normal movement of the wearer to draw air through the suit's interior to cool the wearer and provide breathable air. Filters can be placed in the bellows and suit's air vents, or the suit can be made of a filter material to protect the wearer and the surroundings. The disclosed suit is lighter, less expensive and more mobile than prior-art protective ventilated suits that use powered or externally supplied ventilation and cooling devices.