Abstract: This invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt thereof, in which R-groups R1 to R23, A, Q, U, V, W, X, Y, Z, n, p and q are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.

Abstract: The subject of this disclosure is applying improved techniques to media signal communication as well as control and status exchange to implement a diversity of media interfaces, achieving suitable media communication results despite EM propagation challenges.

Abstract: A fuel-fired furnace incorporates specially designed fuel/air mixing and combustion structures. The fuel/air mixing structure is of a mixing sound-attenuating design and includes a venturi having a perforated sidewall portion and being surrounded by a noise-damping housing chamber communicating with the interior of the venturi via its sidewall perforations. During use of the mixing structure, air is flowed through the venturi in a swirling pattern while fuel is transversely injected internally against the swirling air. The combustion structure includes a burner box housing into which the fuel/air mixture is flowed, combusted, and then discharged as hot combustion gas into and through the heat exchanger tubes. The fuel/air mixture entering the burner box housing initially passes through a non-uniformly perforated diffuser plate functioning to substantially alter in a predetermined manner the relative combustion gas flow rates through the heat exchanger tubes.

Abstract: The invention relates to compounds of formula I wherein R1 and R2 are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-COV-2 with the compound.

Abstract: An improved battery pack of the type comprising an enclosure containing a plurality of battery cells having a flammable volatile electrolyte component. The improvement comprises a trapper material that absorbs the volatile flammable electrolyte component disposed inside the enclosure of the battery pack to absorb flammable volatile electrolyte component that leak from the cells in the enclosure.

Abstract: The present invention relates generally to video or other media transmission, and more particularly, to encoding and decoding of video media that has been transmitted between a video source and a video sink using spread spectrum direct sequence (SSDS) modulation.

Abstract: A biosensor obtains at least a first photoplethysmography (PPG) signal at a first wavelength from a user and a second PPG signal obtained at a second wavelength from the user. The biosensor determines a first R value of the user using the first PPG signal and the second PPG signal and compares the first R value of the user to a normal range of R values for a blood type of the user. The biosensor determines a color of blood of the user using the first, second or another PPG signal and determines an abnormal condition that affects red blood cells of the user in response to the color of the blood and/or in response to the comparison or the first R value of the user to a normal range of R values for a blood type of the user.

Abstract: A conveyor lubricating system includes a lubricant feed line, a lubricant applicator including a lubricant flow regulator and a lubricant brush, and a cantilevered support arm including a first rigid member and a second rigid member connected together by a pivoting joint. The lubricant flow regulator is fluidly connected to the lubricant feed line and the lubricant brush is fluidly connected to the lubricant flow regulator. The lubricant brush includes bristles and a manifold to distribute the conveyor lubricant across a width of the lubricant brush. The first rigid member is secured to the lubricant applicator at an end opposite the pivoting joint and the second rigid member is secured to a stationary support such that the second rigid member is cantilevered over a conveyor and such that the lubricant brush contacts the conveyor. An associated method of applying conveyor lubricant to a conveyor is also provided.

Abstract: Guide systems for installing aircraft structures are disclosed. An example apparatus includes a first guide system structured to removably couple to a first aircraft structure having a first hinge component. A second guide system is structured to removably couple to a second aircraft structure having a second hinge component. The first guide system is to engage the second guide system to enable alignment between the first hinge component and the second hinge component during assembly of the first aircraft structure and the second aircraft structure.

Abstract: An infusion pump for detection of a fluid condition in a flexible tubing is provided. The infusion pump includes a sensor positioned to obtain a value of a tubing force when the tube is received by the infusion pump, a memory storing instructions and a processor. The processor is configured to execute the instructions to generate a force-time curve representative of values of the tubing force obtained by the sensor over time, determine a time-decaying parameter associated with the tubing force characterizing the force-time curve, and determine a fluid pressure value for a fluid in the tube based at least in part on the time-decaying parameter, a material of the tube, a dimension of the tube, and a use history of the tube. A method for using an infusion pump is also provided.

Abstract: A current cable trap includes a first body half having a first end and a second end and a second body half having a third end and a fourth end. The first body half and the second body half are configured to be snapped together about a cable to form a toroid body. The current cable trap includes a first wire and a second wire wrapped around the first body half and the second body half, respectively. The current cable trap includes a first printed circuit board and a second printed board disposed within a first receptacle and a second receptacle, respectively, when the first body half and the second body half are snapped together. The first printed circuit board and the second printed circuit board each provide electrical connection points with wire ends of both the first wire and the second wire.

Abstract: A single space parking meter assembly for retrofitting onto an existing coin vault assembly includes a number of parking meter components enclosed within a protective outer covering that is rotatably or slidably engageable with the coin vault assembly when a bottom surface of the protective outer covering is positioned against or adjacent to an upper surface of the coin vault assembly. A locking mechanism secures the protective outer covering to the coin vault assembly when the protective outer covering is engaged with the coin vault assembly.

Abstract: Medical imaging devices, systems, and methods thereof. The medical imaging system may include a movable station and a gantry. The movable station includes a gantry mount rotatably attached to the gantry. The gantry includes an outer C-arm slidably mounted to and operable to slide relative to the gantry mount, an inner C-arm slidably coupled to the outer C-arm and, an imaging signal transmitter and sensor attached to the C-arms. The two C-arms work together to provide a full 360 degree rotation of the imaging signal transmitter. In embodiment, the imaging signal transmitter and imaging sensor are offset from a center axis of the medical imaging system such that the portable medical imaging system is operable to capture an enlarged field of view.

Abstract: The illustrative embodiments provide a system and method for water-based training. Input is received to begin a training session for a user utilizing a cord system that is anchored. The training session is initiated utilizing the cord system. Sensor measurements associated with user actions and an environment are performed. Feedback is provided to the user during the training session. Metrics regarding the training session are reported from the cord system.

Abstract: A system including a tube and a force sensor coupled to a wall of the tube via a restraining element and configured to obtain a value of a tubing force when the tube is deformed by the restraining element. The system includes a processor to determine parameters for fitting a curve including the value of the tubing force, to determine a fluid pressure value for a fluid in the tube based on the parameters for fitting the curve, and to activate an alarm responsive to the fluid pressure value and to the parameters for fitting the curve when an occlusion condition is identified in the tube. The parameters for fitting the curve comprise at least one time-decaying parameter(s) associated to the tubing force. A method for using the system and a non-transitory computer readable medium including instructions to perform the above method are also provided.

Abstract: Video samples from a camera or cameras of a mobile device are sent as analog levels to a system-on-chip (SoC) or other processor of the device. The analog levels are the analog video samples or be an encoded form of the video samples. The samples are converted to digital and interpolated within the SoC to produce digital RGB samples suitable for display. Or, the analog video samples are interpolated within the SoC using analog processing to produce analog RGB samples. Or, only the G samples are transmitted to the SoC, and processed using analog processing. After processing within the SoC, the samples are sent as analog levels or in encoded form to a corresponding receiver of a display integrated with column drivers. Digital functionality of the DDIC of the display is moved into the SoC or into circuitry separate from, and connected to, the SoC via an MIPI DSI interface.

Abstract: A heating, ventilation, and air conditioning (HVAC) unit including a variable-speed drive and a bypass circuit is provided. Under normal operation, the drive receives line voltages as inputs and provides variable-speed control signals to components of the HVAC unit (for example, a compressor, fan motor, etc.). The drive allows the HVAC to operate at below maximum capacity, which increases the efficiency of the HVAC unit. When a fault condition is detected in the drive, the HVAC unit automatically switches to the bypass circuit such that the line voltages are provided directly to the components. This results in the HVAC unit operating at maximum capacity for a period of time, but allows the HVAC unit to continue operation even when the drive is experiencing the fault condition.

Abstract: There is provided a pipette for aspirating and/or dispensing liquids, comprising a pipette tip and a plunger. The pipette tip has a proximal end and a distal end defining a longitudinal axis therebetween; an aperture at the distal end, and a fluid cavity extending from the aperture at least partially towards the proximal end. The plunger is positioned inside the pipette tip, and extends at least partly between the proximal and distal ends of the pipette tip into the end portion, and is movable towards and away from the aperture to aspirate or dispense fluid from the pipette tip. The pipette tip has an end portion disposed at the distal end, having an inner wall surface extending at an angle of between 2 degrees and 5 degrees relative to the longitudinal axis, for at least 5 mm.

Abstract: There is provided a liquid handling system for dispensing liquid, comprising a pipette tip and a plunger. The pipette tip has: a proximal end and a distal end and a longitudinal axis extending therebetween; an aperture at the distal end, a fluid cavity extending from the aperture at least partly towards the proximal end; an end portion disposed at the distal end, having an inner wall extending at an angle of at most 10 degrees relative to the longitudinal axis. The plunger is positioned inside the pipette tip, configured to extend between the proximal and distal ends of the pipette tip, and movable toward and away from the aperture. The system is configured to carry out at least two different operating methods for dispensing liquid.

Abstract: Apparatus and associated methods relate to a collapsible chair having a collapsible lateral support rod, a pair of front legs, a pair of front chair support rods, and a pair of mechanical junctions configured to couple with an associated pair of poles, such that the collapsible chair is adapted to collapse into an easy-to-carry volume. In an illustrative example, the mechanical junctions may be releasably and/or shock-cord-coupled to various support rods and/or legs. The mechanical junctions may include locking mechanisms to lock the associated poles into a fixed position relative to the mechanical junctions, for example. The collapsible chair may include gear loops for hanging of gear from the collapsible chair. In various embodiments, a collapsible chair may advantageously provide a full size, lightweight chair configured for compact storage in a stowage bag for high portability during outdoor hiking.