Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: A database management engine provides a user interface that allows users to access and modify employee information in a database. The database includes entries for employees, and each database entry includes identifying information about the associated employee. A user can request to modify data within database entries, for instance in order to update information associated with an employee. Responsive to the request, the database management engine identifies liabilities associated with the database modification stemming from associated tax laws. Based on the identified tax liabilities, the engine computes the aggregate tax liability owed by the employer and/or employee. Before modifying a database entry, the engine modifies the user interface to include interface elements detailing the computed aggregate tax liability. The user explicitly can be required to confirm the database modification in view of the aggregate tax liability.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: A method, network node and wireless device (WD) for collision handling, uplink control channel information (UCI) multiplexing and repetition for transport block (TB) transmission on a multi-slot physical uplink shared channel (PUSCH) are disclosed. According to one aspect, a method in a WD includes configuring a multi-slot physical uplink shared channel (PUSCH) by overlapping a multi-slot PUSCH with at least one of another PUSCH and/or a physical uplink control channel (PUCCH).

Abstract: A double-ended high intensity discharge lamp includes a luminous tube which comprises an inner tube and an outer tube. At least one electrical member is securely fastened inside the luminous tube and at least one illuminator supported inside the luminous tube with a distributor connected with the electrical member to receive power and supply the illuminator. The outer tube is another protective shield to stop spreading in explosion of the illuminator.

Abstract: A double-ended high intensity discharge lamp includes a luminous tube and reflective layer covering at a reflective portion provided on at least a portion of aid luminous tube for reflecting light emitted from an illuminator supported in the luminous tube towards the reflective portion to project towards another opposing side of the luminous tube.

Abstract: A double-ended ceramic metal halide lamp includes a luminous tube; at least two illuminators serially connected with each other deposed inside the luminous tube; and at least one ring-shaped retainers arranged between two illuminators to support the illuminators located along a central line of the luminous tube. A manufacturing method for a ceramic metal halide lamp includes following steps: (1) Arrange at least two serially connected illuminators inside an interior of a luminous tube; (2) Seal two ends of the luminous tube by a press sealing technique; and (3) Extract out the gas inside the luminous tube to form an eyelet at a central portion of the luminous tube.

Abstract: A double-ended ceramic metal halide lamp includes a luminous tube; at least two illuminators serially connected with each other deposed inside the luminous tube; and at least one ring-shaped retainers arranged between two illuminators to support the illuminators located along a central line of the luminous tube. A manufacturing method for a ceramic metal halide lamp includes following steps: (1) Arrange at least two serially connected illuminators inside an interior of a luminous tube; (2) Seal two ends of the luminous tube by a press sealing technique; and (3) Extract out the gas inside the luminous tube to form an eyelet at a central portion of the luminous tube.

Abstract: A double-ended high intensity discharge lamp includes a luminous tube and reflective layer covering at a reflective portion provided on at least a portion of aid luminous tube for reflecting light emitted from an illuminator supported in the luminous tube towards the reflective portion to project towards another opposing side of the luminous tube.

Abstract: A double-ended high intensity discharge lamp includes a luminous tube which comprises an inner tube and an outer tube. At least one electrical member is securely fastened inside the luminous tube and at least one illuminator supported inside the luminous tube with a distributor connected with the electrical member to receive power and supply the illuminator. The outer tube is another protective shield to stop spreading in explosion of the illuminator.

Abstract: A double-ended ceramic metal halide lamp includes a luminous tube; at least two illuminators serially connected with each other deposed inside the luminous tube; and at least one ring-shaped retainers arranged between two illuminators to support the illuminators located along a central line of the luminous tube. A manufacturing method for a ceramic metal halide lamp includes following steps: (1) Arrange at least two serially connected illuminators inside an interior of a luminous tube; (2) Seal two ends of the luminous tube by a press sealing technique; and (3) Extract out the gas inside the luminous tube to form an eyelet at a central portion of the luminous tube.

Abstract: A ceramic metal halide lamp includes a luminous tube; an illuminating arrangement having at least two illuminators serially connected with each other and deposed inside the luminous tube; and at least one retainer having at least contacting one end being contacted with an inner surface of the luminous tube to support the illuminators being stability located at a predetermined position inside said luminous tube, wherein the two illuminators are serially connected with each other along a central line of said luminous tube.

Abstract: In order in particular to allow interconnects to be applied to a component (2) by a thermal spraying process in such a way that they are clearly delimited from one another, before the actual spraying process the surface (8) of the component (2) is treated, in particular laser treated, in such a way that a non-adhering region (14) with a nub-like surface structure is formed.

Abstract: This present invention describes a system of waterproof shoes with thermoplastic polyurethane (TPU) insteps, including vamp, instep and sole, in which the waterproof welt coated with waterproof glue is gummed on the seam between the vamp and the sole; the metal section, instep, mid-sole and inner welt is formed in integration by injecting with TPU polyurethane, in which the outer and inner welts are gummed with glue and sewn firmly with threads on the opposite sides of the instep; a metal piece is put between the thin bottom and the filling materials on the bottom side of the instep. The waterproof methods (the waterproof outer surface of the instep, and the waterproof welt coated with waterproof glue and gummed on the seam between the vamp and the sole reach the purpose of saving the materials and labor, obtaining the waterproof effects which is even better than those of the traditional waterproof shoes and may provide more functionality and better visual effects.

Abstract: A supply arrangement selectively operates from either one of dual AC mains supply voltages of, illustratively, 220 or 110 volt RMS AC. When the arrangement operates from the 220 volt AC mains supply voltage, a bridge rectifier, operating as a full-wave rectifier, charges each of series coupled first and second capacitors to one-half the peak of the AC mains supply voltage. During the positive half-period of the AC mains supply voltage, a positive voltage, equal to the difference between the instantaneous mains supply voltage and the DC voltage across the first capacitor is coupled between two terminals of a load such as a degaussing circuit. A corresponding negative difference voltage, is coupled between the two terminals during the other half-period.