Patents by Inventor Robert T. Fitzsimons, Jr.

Robert T. Fitzsimons, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Negative pressure wound therapy article with features
    Patent number: 11376164
    Abstract: An article, including a network of interconnected polymeric strands; wherein each of the interconnected polymeric strands has a first surface adapted to contact a tissue site and a second surface opposite the first surface; wherein at least one of the interconnected polymeric stand has a plurality of features extending from the first surface of the interconnected polymeric strands; wherein at least one of the interconnected polymeric strands is non-linear; a plurality of openings between adjacent interconnected polymeric strands; an adhesive layer in contact with the second surface of the interconnected polymeric strands; and a filler in contact with the adhesive layer, the adhesive layer in between the network of interconnected polymeric strands and the filler; wherein the article is a negative pressure wound therapy article.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: July 5, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Amy K. McNulty, Robert T. Fitzsimons, Jr., Kurt J. Halverson, Bryan A. Baker, Jana Ninkovic, Jie Liu, Minghua Dai, Wei Zhang, Kiu-Yuen Tse, David R. Holm, Graham M. Clarke, Federica Sgolastra
  • LIGAND-FUNCTIONALIZED SUBSTRATES WITH ENHANCED BINDING CAPACITY
    Publication number: 20220120649
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Application
    Filed: December 27, 2021
    Publication date: April 21, 2022
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, JR.
  • Ligand functional substrates
    Patent number: 11279731
    Abstract: A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at pH's near or below the pI's of the biomaterials.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: March 22, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, James I. Hembre, Robert T. Fitzsimons, Jr., George W. Griesgraber, Yi He
  • Peptides for binding epidermal growth factor
    Patent number: 11254716
    Abstract: A polypeptide having a sequence at least 60% identical to SEQ ID NO: 1 (WFEWPYWEMNVPDVWN) is provided. The polypeptide includes no more than 100 total amino acid residues.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: February 22, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Minghua Dai, Amy K. McNulty, Federica Sgolastra, Jie Liu, Jana Ninkovic, Robert T. Fitzsimons, Jr.
  • Ligand-functionalized substrates with enhanced binding capacity
    Patent number: 11237085
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: February 1, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, Jr.
  • Peptides for binding epidermal growth factor
    Patent number: 11034728
    Abstract: A polypeptide having a sequence at least 70% identical to SEQ ID NO: 1 (YVSPGMKNVNWWSHWWHATD) is provided. The polypeptide includes no more than 100 total amino acid residues.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: June 15, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Minghua Dai, Amy K. McNulty, Federica Sgolastra, Jie Liu, Jana Ninkovic, Robert T. Fitzsimons, Jr.
  • NEGATIVE PRESSURE WOUND THERAPY ARTICLE
    Publication number: 20200337907
    Abstract: An article including: a network of interconnected polymeric strands; wherein each of the interconnected polymeric strands has a first surface adapted to contact a tissue site; wherein none of the interconnected polymeric strand has a feature extending from the first surface of the interconnected polymeric strands; wherein at least one of the interconnected polymeric strands is non-linear; and a plurality of openings between adjacent interconnected polymeric strands; wherein the article is a negative pressure wound therapy article
    Type: Application
    Filed: October 30, 2018
    Publication date: October 29, 2020
    Inventors: Robert T. Fitzsimons, Jr., Bryan A. Baker, Jana Ninkovic, Jie Liu, Federica Sgolastra, Minghua Dai, Wei Zhang, Amy K. McNulty
  • LIGAND-FUNCTIONALIZED SUBSTRATES WITH ENHANCED BINDING CAPACITY
    Publication number: 20200209123
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, JR.
  • Peptides for Binding Epidermal Growth Factor
    Publication number: 20200181198
    Abstract: A polypeptide having a sequence at least 70% identical to SEQ ID NO: 1 (YVSPGMKNVNWWSHWWHATD) is provided. The polypeptide includes no more than 100 total amino acid residues.
    Type: Application
    Filed: September 28, 2017
    Publication date: June 11, 2020
    Applicant: 3M Innovative Properties Company
    Inventors: Minghua DAI, Amy K. McNULTY, Federica SGOLASTRA, Jie LIU, Jana NINKOVIC, Robert T. FITZSIMONS, JR.
  • NEGATIVE PRESSURE WOUND THERAPY ARTICLE WITH FEATURES
    Publication number: 20200146892
    Abstract: An article, including a network of interconnected polymeric strands; wherein each of the interconnected polymeric strands has a first surface adapted to contact a tissue site; wherein at least one of the interconnected polymeric strand has a plurality of features extending from the first surface of the interconnected polymeric strands; wherein only one of any two adjacent polymeric strands has a plurality of features extending from the first surface of the interconnected polymeric strands; and wherein at least one of the interconnected polymeric strands is non-linear; and a plurality of openings between adjacent interconnected polymeric strands.
    Type: Application
    Filed: June 12, 2018
    Publication date: May 14, 2020
    Inventors: Amy K. McNulty, Robert T. Fitzsimons, Jr., Kurt J. Halverson, Bryan A. Baker, Jana Ninkovic, Jie Liu, Minghua Dai, Wei Zhang, Graham M. Clarke, Federica Sgolastra
  • PEPTIDES FOR BINDING EPIDERMAL GROWTH FACTOR
    Publication number: 20200123212
    Abstract: A polypeptide having a sequence at least 60% identical to SEQ ID NO: 1 (WFEWPYWEMNVPDVWN) is provided. The polypeptide includes no more than 100 total amino acid residues.
    Type: Application
    Filed: October 2, 2017
    Publication date: April 23, 2020
    Inventors: Minghua Dai, Amy K. McNulty, Federica Sgolastra, Jie Liu, Jana Ninkovic, Robert T. Fitzsimons, JR.
  • Ligand-functionalized substrates with enhanced binding capacity
    Patent number: 10627326
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: April 21, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, Jr.
  • Ligand functionalized polymers
    Patent number: 10526366
    Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: January 7, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Kannan Seshadri, Robert T. Fitzsimons, Jr., James I. Hembre, Catherine A. Bothof, Erin A. Satterwhite, George W. Griesgraber, Yi He, Louis C. Haddad
  • Guanidine-functionalized particles and methods of making and using
    Patent number: 10450333
    Abstract: Guanidine-functionalized particles and methods of making and using such particles.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: October 22, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: George W. Griesgraber, Robert T. Fitzsimons, Jr., Douglas A. Hanggi, Masayuki Nakamura, Jerald K. Rasmussen
  • LIGAND-FUNCTIONALIZED SUBSTRATES WITH ENHANCED BINDING CAPACITY
    Publication number: 20190285523
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Application
    Filed: June 6, 2019
    Publication date: September 19, 2019
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, JR.
  • Ligand-functionalized substrates with enhanced binding capacity
    Patent number: 10352835
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: July 16, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, Jr.
  • NEGATIVE PRESSURE WOUND THERAPY ARTICLE WITH FEATURES
    Publication number: 20190183685
    Abstract: An article, including a network of interconnected polymeric strands; wherein each of the interconnected polymeric strands has a first surface adapted to contact a tissue site; wherein at least one of the interconnected polymeric strand has a plurality of features extending from the first surface of the interconnected polymeric strands; wherein at least one of the interconnected polymeric strands is non-linear; and a plurality of openings between adjacent polymeric strands; wherein the article is a negative pressure wound therapy article.
    Type: Application
    Filed: June 23, 2017
    Publication date: June 20, 2019
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Amy K. McNulty, Robert T. Fitzsimons, Jr., Kurt J. Halverson, Bryan A. Baker, Jana Ninkovic, Jie Liu, Minghua Dai, Wei Zhang, Federica Sgolastra
  • Guanidine-Functionalized Particles and Methods of Making and Using
    Publication number: 20190177342
    Abstract: Guanidine-functionalized particles and methods of making and using such particles.
    Type: Application
    Filed: February 15, 2019
    Publication date: June 13, 2019
    Inventors: George W. Griesgraber, Robert T. Fitzsimons, JR., Douglas A. Hanggi, Masayuki Nakamura, Jerald K. Rasmussen
  • Guanidine-functionalized particles and methods of making and using
    Patent number: 10246472
    Abstract: Guanidine-functionalized particles and methods of making and using such particles.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: April 2, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: George W. Griesgraber, Robert T. Fitzsimons, Jr., Douglas A. Hanggi, Masayuki Nakamura, Jerald K. Rasmussen
  • LIGAND FUNCTIONAL SUBSTRATES
    Publication number: 20190062369
    Abstract: A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at pH's near or below the pI's of the biomaterials.
    Type: Application
    Filed: October 30, 2018
    Publication date: February 28, 2019
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, James I. Hembre, Robert T. Fitzsimons, JR., George W. Griesgraber, Yi He