Abstract: Examples of implantable medical leads or implantable medical systems with implantable medical leads to be anchored to a sacrum are disclosed. The implantable medical leads include a lead body having a distal portion. A fixation mechanism is coupled to the distal portion. An electrode array is mechanically coupled to the fixation mechanism. In one example, the electrode array is directly coupled to the fixation mechanism. The electrode array is electrically coupled to the lead body and configured to generate a stimulation field. The fixation mechanism is configured to anchor the implantable medical lead to a sacrum and effect the stimulation field in a foramen of the sacrum.

Abstract: Systems, devices, and methods for electrical stimulation and removal of electrical stimulation components are disclosed herein. According to some embodiments, the present technology includes a medical device assembly including an expandable member configured to be positioned in a blood vessel. The medical device assembly can further include a lead body having a plurality of electrodes in a distal end region of the lead body, where the electrodes are configured to deliver therapeutic stimulation to surrounding tissue. The medical device assembly can further include one or more engagement members configured to releasably couple the lead body to the expandable member.

Abstract: A system includes memory, and processing circuitry coupled to the memory, the processing circuitry configured to: determine at least one of: a cross-electrical signal measurement at a first electrode on a first lead implanted within a tongue of the patient based on a stimulation signal between a second electrode on the first lead or a second lead implanted within the tongue of the patient and a third electrode, or a strain measurement of at least one of the first lead or the second lead. The processing circuitry is configured to determine movement of the tongue based on at least one of the cross-electrical signal measurement or the strain measurement, and generate information indicative of the movement of the tongue.

Abstract: A medical system for obstructive sleep apnea (OSA) treatment includes therapy delivery circuitry configured to output one or more electrical stimulation signals to a tongue of a patient; sensing circuitry configured to sense one or more compound muscle action potential (CMAP) signals, wherein the one or more CMAP signals are generated in response to the delivery of the one or more electrical stimulation signals; and processing circuitry configured to: cause the therapy delivery circuitry to output the one or more electrical stimulation signals to the tongue; receive information indicative of the one or more CMAP signals from the sensing circuitry; determine, based on the one or more CMAP signals, one or more therapeutic stimulation parameters for the OSA treatment; and cause the therapy delivery circuitry to deliver therapeutic electrical stimulation signals according to at least the determined one or more therapeutic stimulation parameters.

Abstract: Examples of implantable medical leads or implantable medical systems with implantable medical leads to be anchored to a sacrum are disclosed. The implantable medical leads include a lead body having a distal portion. A fixation mechanism is coupled to the distal portion. An electrode array is mechanically coupled to the fixation mechanism. In one example, the electrode array is directly coupled to the fixation mechanism. The electrode array is electrically coupled to the lead body and configured to generate a stimulation field. The fixation mechanism is configured to anchor the implantable medical lead to a sacrum and effect the stimulation field in a foramen of the sacrum.

Abstract: A system includes memory, and processing circuitry coupled to the memory, the processing circuitry configured to: determine at least one of: a cross-electrical signal measurement at a first electrode on a first lead implanted within a tongue of the patient based on a stimulation signal between a second electrode on the first lead or a second lead implanted within the tongue of the patient and a third electrode, or a strain measurement of at least one of the first lead or the second lead. The processing circuitry is configured to determine movement of the tongue based on at least one of the cross-electrical signal measurement or the strain measurement, and generate information indicative of the movement of the tongue.

Abstract: A first medical device for obstructive sleep apnea therapy includes therapy delivery circuitry coupled to a first set of electrodes implantable proximate to a first hypoglossal nerve within a tongue of the patient and configured to deliver a first electrical stimulation signal to the first hypoglossal nerve that causes the tongue of the patient to advance and includes information to communicate to a second medical device implantable within the head or neck of the patient and coupled to a second set of electrodes implantable proximate to a second hypoglossal nerve within the tongue of the patient; and sensing circuitry coupled to the first set of electrodes and configured to receive a second electrical stimulation signal, delivered to the second hypoglossal nerve by the second medical device, that includes information that the second medical device communicates to the first medical device.

Abstract: Examples of implantable medical leads or implantable medical systems with implantable medical leads to be anchored to a sacrum are disclosed. The implantable medical leads include a lead body having a distal portion. A fixation mechanism is coupled to the distal portion. An electrode array is mechanically coupled to the fixation mechanism. In one example, the electrode array is directly coupled to the fixation mechanism. The electrode array is electrically coupled to the lead body and configured to generate a stimulation field. The fixation mechanism is configured to anchor the implantable medical lead to a sacrum and effect the stimulation field in a foramen of the sacrum.

Abstract: Use of non-contact patient monitoring systems to detect, diagnose, monitor and/or adjust therapy for diseases or conditions that have motion-based symptoms, symptoms such as limb tremors, spasms, etc. that can be correlated to diseases or conditions such as Essential tremor, Parkinson's disease, restless leg syndrome, or a diabetic episode. Information garnered by the non-contact monitoring system, information such as location, frequency, severity, and duration of the motion, can be collected and analyzed so that a diagnosis can be made and/or a treatment plan developed and/or adjusted by the patient's caretaker. The non-contact monitoring can provide real-time feedback regarding effectiveness of therapies or treatments, such as, e.g., neurological stimulation.

Abstract: A system may generate a waveform signal indicative of a biometric parameter of a target subject based on motion data associated with the target subject. The motion data may be provided by a depth sensing device and be substantially free of image data. The system may set a threshold condition based on one or more characteristics of the waveform signal. The system may output a control signal to a stimulation device based on the waveform signal satisfying the threshold condition.

Abstract: A medical system for obstructive sleep apnea (OSA) treatment includes therapy delivery circuitry configured to output one or more electrical stimulation signals to a tongue of a patient; sensing circuitry configured to sense one or more compound muscle action potential (CMAP) signals, wherein the one or more CMAP signals are generated in response to the delivery of the one or more electrical stimulation signals; and processing circuitry configured to: cause the therapy delivery circuitry to output the one or more electrical stimulation signals to the tongue; receive information indicative of the one or more CMAP signals from the sensing circuitry; determine, based on the one or more CMAP signals, one or more therapeutic stimulation parameters for the OSA treatment; and cause the therapy delivery circuitry to deliver therapeutic electrical stimulation signals according to at least the determined one or more therapeutic stimulation parameters.

Abstract: A method of replacing a neurostimulator device. The method including explanting a previously implanted neurostimulator device from a site; operably coupling a replacement neurostimulator device to a previously implanted stimulation lead; and implanting a replacement neurostimulator device within the site, the replacement neurostimulator device having a volume of about ten cc's or less, and the previously implanted neurostimulator device having a volume of greater than about ten cc's.

Abstract: A neuromodulation adaptor configured to provide an electrical coupling between an otherwise incompatible stimulation lead and neurostimulator device, the neuromodulation adaptor including a proximal portion having a plurality of electrical conductors spaced apart at a first pitch spacing and configured to electrically engage with a corresponding plurality of electrical terminals of a neurostimulator device, and a distal portion including a stimulation lead port assembly, the stimulation lead port assembly including an upper portion and a lower portion configured to house the plurality of conductor elements and a set screw assembly, the plurality of conductor elements and set screw assembly spaced apart at a second pitch spacing and configured to electrically engage with a corresponding plurality of electrical connectors of a stimulation lead.

Abstract: A first medical device for obstructive sleep apnea therapy includes therapy delivery circuitry coupled to a first set of electrodes implantable proximate to a first hypoglossal nerve within a tongue of the patient and configured to deliver a first electrical stimulation signal to the first hypoglossal nerve that causes the tongue of the patient to advance and includes information to communicate to a second medical device implantable within the head or neck of the patient and coupled to a second set of electrodes implantable proximate to a second hypoglossal nerve within the tongue of the patient; and sensing circuitry coupled to the first set of electrodes and configured to receive a second electrical stimulation signal, delivered to the second hypoglossal nerve by the second medical device, that includes information that the second medical device communicates to the first medical device.

Abstract: An apparatus and method of electrically coupling a previously implanted stimulation lead with a replacement neurostimulator device. The apparatus and method configured to operably couple a proximal portion of a neuromodulation adaptor including a plurality of electrical conductors spaced apart at a first pitch spacing to a corresponding plurality of electrical terminals of a replacement neurostimulator device, and operably couple a distal end of the neuromodulation adaptor including a plurality of conductor elements and an electrically active set screw spaced part of a second pitch spacing to a corresponding plurality of electrical connectors of a previously implanted stimulation lead.

Abstract: An implantable medical lead for sacral modulation therapy is disclosed. The implantable medical lead includes a lead body having a distal portion. An electrode is electrically coupled to the lead body and configured to generate a stimulation field or to sense electrical fields. A fixation mechanism is coupled to the distal portion. The fixation mechanism is configured to anchor the implantable medical lead against an interior wall of a blood vessel. The electrode can effect the stimulation field from within the vessel to stimulate a selected sacral nerve or sense electrical signals such as muscle or nerve responses. Guided implantation of the medical lead or other medical leads through the body to a nerve of interest for neurostimulation via remote sensor is also disclosed.

Abstract: A neuromodulation adaptor configured to provide an electrical coupling between an otherwise incompatible stimulation lead and neurostimulator device, the neuromodulation adaptor including a proximal portion having a plurality of electrical conductors spaced apart at a first pitch spacing and configured to electrically engage with a corresponding plurality of electrical terminals of a neurostimulator device, and a distal portion including a stimulation lead port assembly, the stimulation lead port assembly including an upper portion and a lower portion configured to house the plurality of conductor elements and a set screw assembly, the plurality of conductor elements and set screw assembly spaced apart at a second pitch spacing and configured to electrically engage with a corresponding plurality of electrical connectors of a stimulation lead.

Abstract: Examples of implantable medical leads or implantable medical systems with implantable medical leads to be anchored to a sacrum are disclosed. The implantable medical leads include a lead body having a distal portion. A fixation mechanism is coupled to the distal portion. An electrode array is mechanically coupled to the fixation mechanism. In one example, the electrode array is directly coupled to the fixation mechanism. The electrode array is electrically coupled to the lead body and configured to generate a stimulation field. The fixation mechanism is configured to anchor the implantable medical lead to a sacrum and effect the stimulation field in a foramen of the sacrum.

Abstract: A method of replacing a neurostimulator device. The method including explanting a previously implanted neurostimulator device from a site; operably coupling a replacement neurostimulator device to a previously implanted stimulation lead; and implanting a replacement neurostimulator device within the site, the replacement neurostimulator device having a volume of about ten cc's or less, and the previously implanted neurostimulator device having a volume of greater than about ten cc's.

Abstract: An apparatus and method of electrically coupling a previously implanted stimulation lead with a replacement neurostimulator device. The apparatus and method configured to operably couple a proximal portion of a neuromodulation adaptor including a plurality of electrical conductors spaced apart at a first pitch spacing to a corresponding plurality of electrical terminals of a replacement neurostimulator device, and operably couple a distal end of the neuromodulation adaptor including a plurality of conductor elements and an electrically active set screw spaced part of a second pitch spacing to a corresponding plurality of electrical connectors of a previously implanted stimulation lead.