Patents by Inventor Robert T. Sarisky

Robert T. Sarisky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for suppressing toll-like receptor activity
    Patent number: 8895263
    Abstract: Agents interfering with translocation of Toll-like receptor 3 (TLR3), methods of making and using the foregoing are disclosed.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: November 25, 2014
    Assignee: Janssen Biotech, Inc.
    Inventors: Jarrat Jordan, Sun-Yung Jung, Robert T. Sarisky, Jessica Schreiter
  • CXCL13 antagonists and their use for the treatment of inflammatory diseases
    Patent number: 8277809
    Abstract: Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNF? antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: October 2, 2012
    Assignee: Centocor, Inc.
    Inventors: Peter Bugelski, Anuk Das, Donald E. Griswold, Bailin Liang, Li Li, Robert T. Sarisky, Xiaozhou Shang
  • Toll Like Receptor 3 Antagonists, Methods and Uses
    Publication number: 20120189643
    Abstract: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: March 5, 2012
    Publication date: July 26, 2012
    Inventors: Jill M. Carton, Shizhong Chen, Mark Cunningham, Anuk Das, Karen Duffy, Jill M. Giles-Komar, Theresa J. Goletz, David M. Knight, Roberta Lamb, Mouhamadou L. Mbow, Kristen Picha, Gopalan Raghunathan, Lani San Mateo, Robert T. Sarisky, Vedrana Stojanovic-Susulic, Nicole Stowell, Raymond Sweet, Shanrong Zhao
  • Toll like receptor 3 antagonists, methods and uses
    Patent number: 8153583
    Abstract: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists, and methods of making and using the foregoing are disclosed.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: April 10, 2012
    Inventors: Jill M. Carton, Shizhong Chen, Mark Cunningham, Anuk Das, Karen Duffy, Jill M. Giles-Komar, Theresa J. Goletz, David M. Knight, Roberta Lamb, Mouhamadou L. Mbow, Kristen Picha, Gopalan Raghunathan, Lani San Mateo, Robert T. Sarisky, Vedrana Stojanovic-Susulic, Nicole Stowell, Raymond Sweet, Shanrong Zhao
  • Human immunodeficiency virus gp41 mimetibody polypeptides
    Patent number: 7744897
    Abstract: HIV gp41 mimetibody polypeptides and encoding polynucleotides are disclosed. Methods of utilizing the polypeptides to reduce or inhibit HIV fusion with a cell membrane and entry into target cells are also disclosed.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: June 29, 2010
    Inventors: Susan B. Dillon, Alfred Michael Del Vecchio, Chichi Huang, Karyn T. O'Neil, Robert T. Sarisky
  • Antibody reactive with human toll like receptor 3
    Patent number: 7718778
    Abstract: Toll Like Receptor 3 (TLR3) modulators, such as antibodies, polynucleotides encoding TLR3 antibodies or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: May 18, 2010
    Assignee: Centocor, Inc.
    Inventors: Karen E. Duffy, Chong C. Huang, Roberta Lamb, Mouhamadou L. Mbow, Robert T. Sarisky, Lani San Mateo
  • Methods for Suppressing Toll-Like Receptor Activity
    Publication number: 20100092462
    Abstract: Agents interfering with translocation of Toll-like receptor 3 (TLR3), methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 15, 2010
    Inventors: Jarrat Jordan, Sun-Yung Jung, Robert T. Sarisky, Jessica Schreiter
  • CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases
    Publication number: 20090136512
    Abstract: Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNF? antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
    Type: Application
    Filed: March 31, 2008
    Publication date: May 28, 2009
    Inventors: Peter Bugelski, Deg Griswold, Bailin Liang, Robert T. Sarisky
  • Toll-Like Receptor 3 Modulators and Uses Thereof
    Publication number: 20080299138
    Abstract: Modulators of TLR3 activity and their use are disclosed.
    Type: Application
    Filed: May 23, 2008
    Publication date: December 4, 2008
    Inventors: Karen E. Duffy, Cheneparath Tharachaparamba Ranjith-Kumar, Jarrat L. Jordan, Cheng Chia Kao, Robert T. Sarisky
  • Novel anti-infectives
    Publication number: 20040147739
    Abstract: Compounds useful as HCV anti-infectives having the formula: wherein the formula variables are as defined herein, are disclosed. Also disclosed are methods of making and using the same.
    Type: Application
    Filed: December 2, 2003
    Publication date: July 29, 2004
    Inventors: Deping Chai, Michael G. Darey, Dashyant Dhanak, Kevin J. Duffy, Greg A. Erickson, Duke M. Fitch, Adam T. Gates, Victor K. Johnston, Robert T. Sarisky, Matthew J. Sharp, Antony N. Shaw, Rosanna Tedesco, Kenneth J. Wiggall, Michael N. Zimmerman