Abstract: The valve closure (e.g. an A-type closure) has a closure body (1) for attachment to a container, a gas inlet port (14), a liquid dispensing port (25), and a valve member (6) to sealably close the gas inlet and liquid dispensing ports. An over-pressure relief valve (40) is configured to release gas from within the container in the event that an internal pressure limit is exceeded, and a user-operable depressurising lever (50) is arranged to permit the over-pressure relief valve to be manually opened. The over-pressure relief valve (40) comprises a plunger (53) which is urged against a seat (52) by a spring (57), and the depressurising lever (50) incorporates an abutment (58) for the spring (57). The plunger (53) includes an arrowhead formation (59) by which the depressurising lever (50) engages the plunger to hold the valve open during manual operation.

Abstract: A valve closure for a keg, e.g. incorporating an A-type valve arrangement, has a gas inlet port 11, a liquid dispensing port 12 and a valve member 6 to sealably close the gas inlet and liquid dispensing ports. A venting mechanism includes a detent 23 which can be activated by rotating the valve member 6 after the keg has been filled. This mechanism, when activated, primes a resiliently deflectable circumferential arm 22 to move the detent between the sealing face of the valve member 6 and its valve seat when the valve is next connected for dispensing. When the mechanism is not activated it does not interfere with the normal opening and closing of the valve, e.g.

Abstract: The valve closure (e.g. an A-type closure) has a closure body (1) for attachment to a container, a gas inlet port (14), a liquid dispensing port (25), and a valve member (6) to sealably close the gas inlet and liquid dispensing ports. An over-pressure relief valve (40) is configured to release gas from within the container in the event that an internal pressure limit is exceeded, and a user-operable depressurising lever (50) is arranged to permit the over-pressure relief valve to be manually opened. The over-pressure relief valve (40) comprises a plunger (53) which is urged against a seat (52) by a spring (57), and the depressurising lever (50) incorporates an abutment (58) for the spring (57). The plunger (53) includes an arrowhead formation (59) by which the depressurising lever (50) engages the plunger to hold the valve open during manual operation.

Abstract: The invention relates to a novel use of the antimuscarinic agent glycopyrrolate, for example the salt glycopyrronium bromide. In particular, the invention relates to glycopyrrolate for use as a heart rate lowering agent and more particularly, but not exclusively, for use in patients suffering from respiratory conditions such as chronic obstructive pulmonary disease.

Abstract: The invention relates to a novel use of the antimuscarinic agent glycopyrrolate, for example the salt glycopyrronium bromide. In particular, the invention relates to glycopyrrolate for use as a heart rate lowering agent and more particularly, but not exclusively, for use in patients suffering from respiratory conditions such as chronic obstructive pulmonary disease.

Abstract: The invention relates to a novel use of the antimuscarinic agent glycopyrrolate, for example the salt glycopyrronium bromide. In particular, the invention relates to glycopyrrolate for use as a heart rate lowering agent and more particularly, but not exclusively, for use in patients suffering from respiratory conditions such as chronic obstructive pulmonary disease.

Abstract: There is provided a sheet driver for use in a medicament dispenser including a medicament carrier having a plurality of pockets for containing medicament wherein said pockets are spaced along the length of and defined between first and second sheets secured to each other and separable by drivable pulling action, the sheet driver comprising a base; ascending from the base, a shaft defining a rotational axis; on the base, a drive surface for receipt of drive to rotate the base about the rotational axis; about the shaft, a torsion spring defining first and second spring legs; mounting about the shaft and the torsion spring for rotation about the rotational axis, a hub defining a hub surface for receipt of a sheet of the medicament carrier. A first leg receiver of the base receives the first spring leg of the torsion spring and a second leg receiver of the hub receives the second spring leg of the torsion spring such that relative rotation of the base and the hub results in tensioning of the torsion spring.

Abstract: A fluid dispensing device for dispensing a fluid product having a dispensing outlet from which the fluid product is dispensable, a supply of the fluid product, a dispensing member mounted for movement in a dispensing direction along an axis X-X from a first position to a second position which causes a dose of the fluid product in the supply to be dispensed from the dispensing outlet and a finger-operable actuator member mounted for movement in an actuating direction which is generally transverse to the axis.

Abstract: Water supplied from a bottle 1 is pre-chilled in a reservoir 3. A two-part water pump 11 transfers water under pressure through a jet nozzle 14 into an oxygen space 17 in a PET pressure vessel 12, which entrains oxygen into the water. The pressure vessel is received in a conductive holder 18 and is cooled by a peltier element 19 provided with cooling fins 20. The holder 18 forms a capacitive level sensor with a probe 32 inside the vessel, which starts the pump 11 when oxygenated water is drawn off via a draw tube 28 and discharge valve 31. When the water level in the oxygenating vessel is restored a solenoid valve 25 opens to restore the oxygen pressure in the vessel. For hygiene purposes the pumping body can be removed from the pump motor and replaced together with the reservoir 3 and oxygenating vessel 12 along with the associated tubing.

Abstract: Water supplied from a bottle 1 is pre-chilled in a reservoir 3. A two-part water pump 11 transfers water under pressure through a jet nozzle 14 into an oxygen space 17 in a PET pressure vessel 12, which entrains oxygen into the water. The pressure vessel is received in a conductive holder 18 and is cooled by a peltier element 19 provided with cooling fins 20. The holder 18 forms a capacitive level sensor with a probe 32 inside the vessel, which starts the pump 11 when oxygenated water is drawn off via a draw tube 28 and discharge valve 31. When the water level in the oxygenating vessel is restored a solenoid valve 25 opens to restore the oxygen pressure in the vessel. For hygiene purposes the pumping body can be removed from the pump motor and replaced together with the reservoir 3 and oxygenating vessel 12 along with the associated tubing.

Abstract: Liquid is supplied from a bottle B to a discharge outlet 8 via a molded plastics reservoir 15 by pressurizing the bottle using an air pump 22. A pressure sensor responds to a rise in air pressure supplied to the bottle by shutting off the pump. Liquid is removed from the reservoir through a dip tube 17 having a main outlet 18 adjacent to the bottom of the reservoir and a smaller auxiliary outlet 21 adjacent to the top of the reservoir. The upper region of the reservoir is received in a finned heat-conducting holder 16 provided with a thermoelectric cooling element. For hygienic purposes the bottle has a connector 12 which can be replaced together with the reservoir 15 and associated supply tubes 24, 13, 14, 17 and 19. A temperature-control mixer 51 may be to mix liquid from the reservoir with liquid from the bottle.

Abstract: Liquid is supplied from a bottle B to a discharge outlet 8 via a molded plastics reservoir 15 by pressurizing the bottle using an air pump 22. A pressure sensor responds to a rise in air pressure supplied to the bottle by shutting off the pump. Liquid is removed from the reservoir through a dip tube 17 having a main outlet 18 adjacent to the bottom of the reservoir and a smaller auxiliary outlet 21 adjacent to the top of the reservoir. The upper region of the reservoir is received in a finned heat-conducting holder 16 provided with a thermoelectric cooling element. For hygienic purposes the bottle has a connector 12 which can be replaced together with the reservoir 15 and associated supply tubes 24, 13, 14, 17 and 19. A temperature-control mixer 51 may be to mix liquid from the reservoir with liquid from the bottle.

Abstract: Liquid is supplied from a bottle B to a discharge outlet 8 via a molded plastics reservoir 15 by pressurizing the bottle using an air pump 22. A pressure sensor responds to a rise in air pressure supplied to the bottle by shutting off the pump. Liquid is removed from the reservoir through a dip tube 17 having a main outlet 18 adjacent to the bottom of the reservoir and a smaller auxiliary outlet 21 adjacent to the top of the reservoir. The upper region of the reservoir is received in a finned heat-conducting holder 16 provided with a thermoelectric cooling element. For hygienic purposes the bottle has a connector 12 which can be replaced together with the reservoir 15 and associated supply tubes 24, 13, 14, 17 and 19. A temperature-control mixer 51 may be to mix liquid from the reservoir with liquid from the bottle.

Abstract: Liquid is supplied from a bottle B to a discharge outlet 8 via a moulded plastics reservoir 15 by pressurising the bottle using an air pump 22. A pressure sensor responds to a rise in air pressure supplied to the bottle by shutting off the pump. Liquid is removed from the reservoir through a dip tube 17 having a main outlet 18 adjacent to the bottom of the reservoir and a smaller auxiliary outlet 21 adjacent to the top of the reservoir. The upper region of the reservoir is received in a finned heat-conducting holder 16 provided with a thermoelectric cooling element. For hygienic purposes the bottle has a connector 12 which can be replaced together with the reservoir 15 and associated supply tubes 24, 13, 14, 17 and 19. A temperature-control mixer 51 may be to mix liquid from the reservoir with liquid from the bottle.

Abstract: A water dispenser which dispenses liquid from an inverted bottle includes a housing 31 provided with a mounting arrangement for the bottle. A feed tube incorporated in a removably mounted manifold body is positioned to project into the neck of the bottle to conduct water to a reservoir from which water is discharged through a valve 80. The valve includes a pinch bar 106 acting on a flexible plastics or rubber tube 96 which can easily be replaced. The outlet end of the tube is recessed behind the housing 31 to prevent accidental hand contact. Liquid discharged from the bottle is replaced by air which passes through a one-way float valve mounted on the manifold body for removal therewith, and the float valve incorporates an air filter.

Abstract: Apparatus for dispensing liquid from an inverted bottle having a neck through which the liquid is discharged, is provided with a mount 32 having a feed tube 34 to project into the neck of the bottle. The feed tube forms part of a reservoir 152 which incorporates a drainage channel 153 to sealably receive the neck of the bottle with closure of drain valve 144. Water travels from the feed tube 34 to a cold reservoir 160 comprising a flexible bag 163 received within a fixed rigid outer 162. Cooled water leaves the bag 163 to a discharge valve 168. The feed tube 34 may also supply a hot water reservoir (FIG. 3 ) which is also replaceable. To maintain strict hygiene, the manifold 152 and both reservoirs are completely replaced at intervals together with the interconnecting pipework.

Abstract: The apparatus is intended for dispensing liquid from an inverted container having a neck through which the liquid is discharged, and includes a housing 31 provided with a mounting arrangement 32 for receiving and supporting the inverted container. A feed tube 34 is arranged to project into the neck of said liquid container to conduct liquid to a reservoir, and cover flaps 62 and 63 are biassed together by tension springs 69 and 70 to cover the feed tube 34 upon removal of the liquid container. The feed tube may alternatively be covered by a resilient diaphragm.