Patents by Inventor Robert Tarran

Robert Tarran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide inhibitors of calcium channels
    Patent number: 10894811
    Abstract: The present invention relates to fragments of SPLUNC1 protein that bind to calcium channels and inhibit calcium influx into airway smooth muscle and other cells. The invention further relates to methods for regulating calcium influx and treating or preventing disorders responsive to modulating calcium influx through calcium channels.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: January 19, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Tongde Wu
  • PEPTIDE INHIBITORS OF SODIUM CHANNELS
    Publication number: 20190071468
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Application
    Filed: September 12, 2018
    Publication date: March 7, 2019
    Inventors: Robert Tarran, Dale J. Christensen
  • PEPTIDE INHIBITORS OF CALCIUM CHANNELS
    Publication number: 20190062386
    Abstract: The present invention relates to fragments of SPLUNC1 protein that bind to calcium channels and inhibit calcium influx into airway smooth muscle and other cells. The invention further relates to methods for regulating calcium influx and treating or preventing disorders responsive to modulating calcium influx through calcium channels.
    Type: Application
    Filed: February 22, 2017
    Publication date: February 28, 2019
    Inventors: Robert Tarran, Tongde Wu
  • Peptide inhibitors of sodium channels
    Patent number: 10150796
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: December 11, 2018
    Assignees: University of North Carolina at Chapel Hill, Spyryx Biosciences, Inc.
    Inventors: Robert Tarran, Dale J. Christensen
  • Peptide Inhibitors of Sodium Channels
    Publication number: 20170327538
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Application
    Filed: May 10, 2017
    Publication date: November 16, 2017
    Inventors: Robert Tarran, Dale J. Christensen
  • Peptide inhibitors of sodium channels
    Patent number: 9796768
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: October 24, 2017
    Assignees: Spryx Biosciences, Inc., The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Dale J. Christensen
  • Peptide Inhibitors of Sodium Channels
    Publication number: 20170226180
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Application
    Filed: April 21, 2017
    Publication date: August 10, 2017
    Inventors: Robert Tarran, Dale J. Christensen
  • REGULATION OF SODIUM CHANNELS BY PLUNC PROTEINS
    Publication number: 20170080053
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Application
    Filed: December 6, 2016
    Publication date: March 23, 2017
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson
  • Regulation of sodium channels by PLUNC proteins
    Patent number: 9549967
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: January 24, 2017
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson
  • REGULATION OF SODIUM CHANNELS BY PLUNC PROTEINS
    Publication number: 20160159879
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Application
    Filed: December 16, 2015
    Publication date: June 9, 2016
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson
  • Peptide Inhibitors of Sodium Channels
    Publication number: 20160102121
    Abstract: The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
    Type: Application
    Filed: October 8, 2015
    Publication date: April 14, 2016
    Inventors: Robert Tarran, Dale J. Christensen
  • Regulation of sodium channels by PLUNC proteins
    Patent number: 9127040
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: September 8, 2015
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson
  • Regulation of Sodium Channels by PLUNC Proteins
    Publication number: 20140228276
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Application
    Filed: September 19, 2012
    Publication date: August 14, 2014
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson
  • Regulation of Sodium Channels by PLUNC Proteins
    Publication number: 20120115795
    Abstract: The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.
    Type: Application
    Filed: May 28, 2010
    Publication date: May 10, 2012
    Inventors: Robert Tarran, Monroe Jack Stutts, Scott Donaldson