Patents by Inventor Robert Thai

Robert Thai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cysteine-free efficient Technetium (Tc) or Rhenium (Re) chelating peptide tags and their use
    Patent number: 9234001
    Abstract: The present invention relates to a peptide tag which can be used to bind a Technetium (Tc) or Rhenium (Re) radionuclide to a protein of interest which comprises the peptide tag and allows the imaging of such a tagged protein. In particular the present invention relates to a peptide tag which chelates a Tc or Re atom but which does not comprise a Cysteine residue.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: January 12, 2016
    Assignee: Commissariat a L'Energie Atomique et aux Energies Alternatives
    Inventors: Loïc Le Clainche, Alain Lecoq, Sophie Zinn-Justin, Robert Thai, Michel Masella, Philippe Cuniasse
  • Stabilized Tat antigen and the use thereof for anti-HIV vaccination
    Patent number: 8501193
    Abstract: The invention relates to a vaccine composition comprising at least one type of anti-HIV vaccine composition containing at least one type of stabilized Tat antigen and to the use thereof for preventing and/or treating a human HIV infection.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: August 6, 2013
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Pascal Drevet, Evelyne Lajeunesse, Alain Lecoq, Michel Leonetti, André Menez, Gervaise Moine, Robert Thai
  • CYCLODIPEPTIDE SYNTHETASE AND ITS USE FOR SYNTHESIS OF CYCLO(Tyr-Xaa) CYCLODIPEPTIDES
    Publication number: 20110318781
    Abstract: Isolated, natural or synthetic polynucleotide and polypeptide encoded by said polynucleotide, that is involved in the synthesis of cyclodipeptides, recombinant vector comprising said polynucleotide or any substantially homologous polynucleotide, host cell modified with said polynucleotide or said recombinant vector and also methods for in vitro and in vivo synthesizing cyclodipeptides, in particular cyclo(Tyr-Xaa) cyclodipeptides, wherein Xaa is any amino acid and their derivatives and applications thereof.
    Type: Application
    Filed: June 21, 2011
    Publication date: December 29, 2011
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD 11, KYOWA HAKKO BIO CO., LTD
    Inventors: Pascal BELIN, Muriel GONDRY, Robert THAI, Jean-Luc PERNODET, Roger GENET
  • Cysteine-Free Efficient Technetium (Tc) or Rhenium (Re) Chelating Peptide Tags and Their Use
    Publication number: 20110318827
    Abstract: The present invention relates to a peptide tag which can be used to bind a Technetium (Tc) or Rhenium (Re) radionuclide to a protein of interest which comprises the peptide tag and allows the imaging of such a tagged protein. In particular the present invention relates to a peptide tag which chelates a Tc or Re atom but which does not comprise a Cysteine residue.
    Type: Application
    Filed: December 28, 2009
    Publication date: December 29, 2011
    Inventors: Loïc Le Clainche, Alain Lecoq, Sophie Zinn-Justin, Robert Thai, Michel Masella, Philippe Cuniasse
  • CYCLODIPEPTIDE SYNTHASES (CDSS) AND THEIR USE IN THE SYNTHESIS OF LINEAR DIPEPTIDES
    Publication number: 20100279334
    Abstract: Use of CDSs in the synthesis of linear dipeptides, and applications thereof for the in vivo and in vitro synthesis of linear dipeptides, in particular Phe-Leu, Leu-Phe, Phe-Phe, Phe-Tyr, Tyr-Phe, Leu-Leu, Leu-Tyr, Tyr-Leu, Phe-Met, Met-Phe, Leu-Met, Met-Leu, Tyr-Met, Met-Tyr, Met-Met, Tyr-Tyr, Ile-Met, Met-Ile, Leu-Ile, Ile-Leu using the corresponding polynucleotides.
    Type: Application
    Filed: October 31, 2007
    Publication date: November 4, 2010
    Applicants: KYOWA HAKKO BIO CO., LTD, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD 11, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Ludovic Sauguet, Robert Thai, Pascal Belin, Alain Lecoq, Roger Genet, Jean-Luc Pernodet, Muriel Gondry
  • Cyclodipeptide Synthetase and its use for Synthesis of Cyclo(Tyr-Xaa) Cyclodipeptides
    Publication number: 20100055737
    Abstract: Isolated, natural or synthetic polynucleotide and polypeptide encoded by said polynucleotide, that is involved in the synthesis of cyclodipeptides, recombinant vector comprising said polynucleotide or any substantially homologous polynucleotide, host cell modified with said polynucleotide or said recombinant vector and also methods for in vitro and in vivo synthesizing cyclodipeptides, in particular cyclo(Tyr-Xaa) cyclodipeptides, wherein Xaa is any amino acid and their derivatives and applications thereof.
    Type: Application
    Filed: April 26, 2006
    Publication date: March 4, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Pascal Belin, Muriel Gondry, Robert Thai, Jean-Luc Pernodet, Roger Genet
  • Cyclodipeptide Synthetases and Their Use for Synthesis of Cyclo(Leu-Leu) Cyclodipeptide
    Publication number: 20090264616
    Abstract: Isolated, natural or synthetic polynucleotides and the polypeptides encoded by said polynucleotides, that are involved in the synthesis of cyclodipeptides, the recombinant vectors comprising said polynucleotides or any substantially homologous polynucleotides, the host cell modified with said polynucleotides or said recombinant vectors and also methods for in vitro and in vivo synthesizing cyclo(Leu-Leu) cyclodipeptide and its derivatives and applications thereof.
    Type: Application
    Filed: April 26, 2006
    Publication date: October 22, 2009
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE, KYOWA HAKKO BIO CO., LTD., UNIVERSITE PARIS SUD 11, CENTRE NATIONAL DE LA RECHERCHE SEIENTIFIQUE
    Inventors: Muriel Gondry, Robert Thai, Pascal Belin, Roger Genet, Jean-Luc Pernodet