Abstract: A hand held spray dispenser in which air and liquid are pressurised towards a mixing chamber by energy generated by a manual activation element that is rotated with a unidirectional twist to energise one or more energy storage bodies, energy from which is released to generate sufficient air pressure and air flow and sufficient liquid flow for a spray to be formed from the air-liquid mixture.

Abstract: The application is directed to methods and devices for estimating corrosion of a material. One of the methods includes obtaining data regarding corrosion. The data is obtained from various sources, such as but not limited to sensors and observational data. The data is then trained to provide for a more complete data set. The trained data is then used to estimate the expected amount of corrosion for a given situation.

Abstract: Provided are X-ray and metal detectable thermoset composites and methods of detecting the same. The present X-ray and metal detectable thermoset composites may be formed into trays, sheets, or other substrates suitable for use in food or pharmaceutical processing or manufacturing.

Abstract: Spoolable tubing suitable for use in the oil industry, and more particularly spoolable composite tubing with the ability to withstand high stress and high cracking resistance.

Abstract: Embeddable extensions of the functionality of email and calendaring applications are described herein. An originating email and calendaring application formats meeting items to include extensible content, e.g., within the body field of the meeting item. Recipient email and calendaring applications receive the meeting items and, depending on whether they are configured to provide an extended functionality, will either deploy the extensible content item according to the extended functionality or present the extensible content item according to a standardized functionality. The body field includes the extensible content item according to the standardized functionality that is interpretable by configured clients to provide the extended functionality.

Abstract: 1. Fingerprint Kill Switch (FPKS) is a kill switch for your vehicle that does not communicate with your ECU (engine control unit), instead it is directly wired to the ignition and starter wire of your vehicle. Fingerprint Kill Switch (FPKS) cuts off power to the starter until an authorized fingerprint(s) is submitted then and only then may you use the key and start the vehicle; however, the window to start your vehicle is only open for a short amount of time from (from 0.5 seconds to 30 seconds). If you are unable to start your vehicle in time, all you must do is input your fingerprint(s) again. Fingerprint Kill Switch (FPKS) operates differently from other products due to its simplicity, all it does is block vehicle ignition start up from anyone who does not have an authorized fingerprint(s), Fingerprint Kill Switch (FPKS) is unique due to its simplistic design that does not require communication with the onboard vehicle computers.

Abstract: The nonlinearity of power amplifiers (PAs) has been a severe constraint in performance of modern wireless transceivers. This problem is even more challenging for the fifth generation (5G) cellular system since 5G signals have extremely high peak to average power ratio. Nonlinear equalizers that exploit both deep neural networks (DNNs) and Volterra series models are provided to mitigate PA nonlinear distortions. The DNN equalizer architecture consists of multiple convolutional layers. The input features are designed according to the Volterra series model of nonlinear PAs. This enables the DNN equalizer to effectively mitigate nonlinear PA distortions while avoiding over-fitting under limited training data. The non-linear equalizers demonstrate superior performance over conventional nonlinear equalization approaches.

Abstract: A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body.

Abstract: Methods, systems, and media for presenting caption information based on volume setting adjustments are provided.

Abstract: A system and method for rapidly aging using a closed system to process an unaged distilled spirit to produce rapidly aged spirits over a very fast period of time. A processing vessel dedicated to holding the unaged spirit and mixing the unaged spirit with charred wood staves is provided. A computer application is used to schedule the sequence of steps for a recurring period of time to age the unaged spirit. The closed system uses a first production tank and a second production tank that are partially filled with liquid and are connected to the processing vessel. Compressed pressurized air is added and released over a period of time to add and release pressure to the second production tank, and to influence the flow of oxygen between the second production tank and the processing vessel in order to age the contents of the processing vessel with minimal vapor loss from the aging spirit.

Abstract: The disclosure provides apparatus and methods of use pertaining to a biomechanical finger brace assembly. In one embodiment, the assembly includes a coupling tip, a proximal ring configured to concentrically receive a user's finger, a distal ring configured to concentrically receive the finger, and a rocker formed in an H-shape. The distal ring and the rocker are pivotally suspended between a proximal coordinated pivot point anchored on the proximal ring and a distal coordinated pivot point anchored on the coupling tip, such that movements of the finger within the proximal ring articulate the distal ring together with the rocker to articulate the coupling tip. The coupling tip may include an open end or an enclosed recess to accept a minimally-amputated or non-amputated finger. Other embodiments are also disclosed.

Abstract: A sales person at a retail store which traditionally does not sell paint assists a consumer in selecting and purchasing a non-paint product and thereafter employs a computer terminal and display in conjunction with a website operated by a paint manufacturer to provide a paint color recommendation to the consumer. The sales person may thereafter respond to consumer selection of a particular paint color by employing an on-line electronic ordering tool to transmit a paint order to an order processing terminal located at a paint manufacturer facility. Thereafter, the paint manufacturer may proceed to process the order, perform tinting and shaking steps to formulate paint of the particular color, package the tinted paint, and cause the packaged paint to be shipped to the consumer.

Abstract: A polynucleotide, comprising the following base sequences: (a) a base sequence encoding a fusion protein of a nuclease-deficient CRISPR effector protein and a transcription repressor, and (b) a base sequence encoding a guide RNA targeting a continuous region of 18 to 24 nucleotides in length in a region set forth in SEQ ID NO: 54, 55, 56, 57, 68, 153 or 97 in the expression regulatory region of human MAPT gene. are expected to be useful for treating or preventing tauopathy including Alzheimer's disease.

Abstract: In an aspect, a first controller module of a mobile device controller can be engaged with a first side of a mobile device of a user. A second controller module of the mobile device controller can be engaged with a second side of the mobile device. One or more mobile device controller characteristics associated with characteristics of the mobile device controller can be transmitted from the mobile device controller to the mobile device. A client application on the mobile device can be modified by a first data processor based on the one or more mobile device controller characteristics. The modified client application can be provided by the first data processor to the user in the mobile device, and the user can interact with the modified client application using the mobile device controller. Related systems, apparatus, techniques, and articles are also described.

Abstract: Embeddable extensions of the functionality of email and calendaring applications are described herein. An originating email and calendaring application formats meeting items to include extensible content, e.g., within the body field of the meeting item. Recipient email and calendaring applications receive the meeting items and, depending on whether they are configured to provide an extended functionality, will either deploy the extensible content item according to the extended functionality or present the extensible content item according to a standardized functionality. The body field includes the extensible content item according to the standardized functionality that is interpretable by configured clients to provide the extended functionality.

Abstract: The present invention relates to 8-substituted diaryl xanthines and pharmaceutical compositions thereof that are antagonists of A2A and/or A2B adenosine receptors (ARs).

Abstract: Systems, apparatuses, and methods are described for deploying upstream bandwidth upgrade of devices per home basis. The impact of the upstream bandwidth upgrade on the devices may be pre-estimated based on remotely monitoring and/or analyzing performance data of the devices collected during transmissions of test signals (e.g., a burst of upstream transmissions) in real-time from the devices operating under different modes of operations. The burst of upstream transmissions using a small bandwidth (e.g., 1.6 MHz) may be limited to a short duration of time (e.g., 5 seconds) so that on-going services provided by the devices are not substantially interrupted. The upstream bandwidth of the devices, based on the pre-estimated impact, may be upgraded, left unaltered, or downgraded.

Abstract: The disclosure provides apparatus and methods of use pertaining to a biomechanical finger brace assembly. In one embodiment, the assembly includes a coupling tip, a proximal ring configured to concentrically receive a user's finger, a distal ring configured to concentrically receive the finger, and a rocker formed in an H-shape. The distal ring and the rocker are pivotally suspended between a proximal coordinated pivot point anchored on the proximal ring and a distal coordinated pivot point anchored on the coupling tip, such that movements of the finger within the proximal ring articulate the distal ring together with the rocker to articulate the coupling tip. The coupling tip may include an open end or an enclosed recess to accept a minimally-amputated or non-amputated finger. Other embodiments are also disclosed.

Abstract: The devices, methods and systems are described for providing controlled amounts of gas, gas pressure and vacuum to microfluidic devices the culturing of cells under flow conditions. The devices, methods, and systems contemplated here may also be used to control the environment surrounding the microfluidic devices; offer user control over experiments comprising microfluidic devices, such as the ability to directly or remotely control experiment conditions; and comprise information aggregation and transmission, such that experimental data may be collected, stored, aggregated and transmitted to users.