Patents by Inventor Robert V. Coombs

Robert V. Coombs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzindazoles
    Patent number: 4042704
    Abstract: The compounds are benz[f]indazoles, e.g., 3-(p-chlorophenyl)-1-methylbenz[f]indazole, and are useful as fertility control agents.
    Type: Grant
    Filed: March 18, 1976
    Date of Patent: August 16, 1977
    Assignee: Sandoz, Inc.
    Inventor: Robert V. Coombs
  • 9-.alpha.-methyl-steroids
    Patent number: 3997574
    Abstract: The compounds are 13-(lower)alkyl-9.alpha.-methyl-17.alpha.-propadienylgona-4-en-17.beta.-ol -3-ones and derivatives thereof, e.g. 9.alpha.-methyl-17.alpha.-propadienylestra-17.beta.-ol-3-one, and are useful as progestational agents.
    Type: Grant
    Filed: September 5, 1974
    Date of Patent: December 14, 1976
    Assignee: Sandoz, Inc.
    Inventors: Robert V. Coombs, Eugene E. Galantay
  • Substituted naphtho pyrazoles
    Patent number: 3959308
    Abstract: Substituted naphtho [1,2-c] pyrazoles, e.g., 3-(4-pyridyl)-2H-naphtho[1,2-c]-pyrazole, are useful as non-estrogenic anti-fertility agents.
    Type: Grant
    Filed: June 27, 1974
    Date of Patent: May 25, 1976
    Assignee: Sandoz, Inc.
    Inventors: Robert V. Coombs, William J. Houlihan
  • 1-Tertiary-butyl-3-morpholino-3-phenyl-2,1-benzisoxaxolines
    Patent number: 3931172
    Abstract: The invention discloses 1-tertiary-butyl-3-morpholino-3-phenyl-2,1-benzisoxazolines having pharmacological activity in animals and useful, for example, as hypolipidemic agents. The compounds may be prepared by reacting a 1-tertiary-butyl-3-phenyl-2,1-benzisoxazolium quaternary salt, e.g., 1-tertiary-butyl-3-phenyl-2,1-benzisoxazolium tetrafluoroborate with morpholine. The 1-tertiary-butyl-3-phenyl-2,1-benzisoxazolium quaternary salt may be prepared by reaction of a corresponding 3-phenyl-2,1-benzisoxazole with tertiary-butanol in the presence of a strong inorganic acid.
    Type: Grant
    Filed: February 25, 1974
    Date of Patent: January 6, 1976
    Assignee: Sandoz Inc.
    Inventors: Robert V. Coombs, Goetz E. Hardtmann