Patents by Inventor Robert V. Mulkern

Robert V. Mulkern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10395369
    Abstract: Methods and apparatus for processing magnetic resonance imaging (MRI) data to perform bone segmentation. MRI data comprising a set of gradient-echo images acquired throughout a spin echo is processed to generate a bone segmentation image. The bone segmentation image is generated based, at least in part, on at least two images in the set of gradient-echo images, wherein the at least two images include a first image corresponding to a beginning portion of the spin echo and a second image corresponding to a central portion of the spin echo.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: August 27, 2019
    Assignee: Children's Medical Center Corporation
    Inventors: Robert V. Mulkern, Delma Jarrett, Mukund Balasubramanian
  • Publication number: 20180150953
    Abstract: Methods and apparatus for processing magnetic resonance imaging (MRI) data to perform bone segmentation. MRI data comprising a set of gradient-echo images acquired throughout a spin echo is processed to generate a bone segmentation image. The bone segmentation image is generated based, at least in part, on at least two images in the set of gradient-echo images, wherein the at least two images include a first image corresponding to a beginning portion of the spin echo and a second image corresponding to a central portion of the spin echo.
    Type: Application
    Filed: May 26, 2016
    Publication date: May 31, 2018
    Applicant: Children's Medical Center Corporation
    Inventors: Robert V. Mulkern, Delma Jarrett, Mukund Balasubramanian
  • Patent number: 8473028
    Abstract: The present invention provides a method for producing density-compensated MR images having improved signal-to-noise ratio and with reduced computational burden. The method includes sampling MR data using a rotationally symmetric acquisition trajectory, generating a cross-correlation matrix, and applying a discreet Fourier transform (DFT) to the acquired MR data and the cross correlation matrix. The method further includes employing the transformed MR data and transformed cross-correlation matrix in a linear system to produce a set of density-compensated transformed MR data, which may transformed into density compensated MR data by application of an inverse DFT. The density compensated MR data may be reconstructed by a variety of techniques to produce density compensated images.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: June 25, 2013
    Assignees: The Brigham and Women's Hospital, Children's Medical Center Corporation
    Inventors: Dimitrios Mitsouras, Frank J. Rybicki, Robert V. Mulkern
  • Publication number: 20100305424
    Abstract: The present invention provides a method for producing density-compensated MR images having improved signal-to-noise ratio and with reduced computational burden. The method includes sampling MR data using a rotationally symmetric acquisition trajectory, generating a cross-correlation matrix, and applying a discreet Fourier transform (DFT) to the acquired MR data and the cross correlation matrix. The method further includes employing the transformed MR data and transformed cross-correlation matrix in a linear system to produce a set of density-compensated transformed MR data, which may transformed into density compensated MR data by application of an inverse DFT. The density compensated MR data may be reconstructed by a variety of techniques to produce density compensated images.
    Type: Application
    Filed: November 21, 2008
    Publication date: December 2, 2010
    Inventors: Jack M. Cook, Dimitrios Mitsouras, Frank J. Rybicki, Robert V. Mulkern
  • Publication number: 20010039377
    Abstract: Quantified differences, such as chi2 error parameters, between a mono-exponential, logarithmic best fit of a series of line scan diffusion-weighted magnetic resonance signals taken over a range of b-factors between about 100 and about 5000 sec/mm2 are obtained. The quantified differences so generated are displayed as an image wherein the brightness of each pixel depends upon the size of its associated quantified difference. The resulting image is characterized by high signal to noise ratio and distinctness between varying tissue types.
    Type: Application
    Filed: March 30, 2001
    Publication date: November 8, 2001
    Inventors: Stephan E. Maier, Robert V. Mulkern