Patents by Inventor Robert Van Reis

Robert Van Reis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7323553
    Abstract: The present invention relates to a method for protein purification that involves the combination of non-affinity chromatography with HPTFF.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: January 29, 2008
    Assignee: Genentech, Inc.
    Inventors: Robert Fahrner, Deborah Follman, Benedicte Lebreton, Robert van Reis
  • Publication number: 20060234226
    Abstract: The present invention relates to a method for protein purification that involves the combination of non-affinity chromatography with HPTFF.
    Type: Application
    Filed: April 25, 2003
    Publication date: October 19, 2006
    Inventors: Robert Fahner, Deborah Follman, Benedicte Lebreton, Robert Van Reis
  • Publication number: 20060157412
    Abstract: The invention relates to charged filtration membranes and their use for separation of a protein from solvent, low molecular weight solutes or a mixture of proteins. Modification of the membranes to generate charge includes modification of membrane pores to alter charge within a pore and alter the size of a pore. Consequently, the protein is separated from other solutes in a mixture based on size as well as net protein charge and membrane charge.
    Type: Application
    Filed: September 29, 2005
    Publication date: July 20, 2006
    Inventor: Robert van Reis
  • Publication number: 20030229212
    Abstract: The present invention relates to a method for protein purification that involves the combination of non-affinity chromatography with HPTFF.
    Type: Application
    Filed: April 25, 2003
    Publication date: December 11, 2003
    Inventors: Robert Fahrner, Deborah Follman, Benedicte Lebreton, Robert van Reis
  • Publication number: 20030121854
    Abstract: The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small molecular weight ligands and the species of interest. The small molecular weight ligands employed in the present invention function to interact with a species of interest in a mixture of different species through either affinity, hydrophobic and/or ionic interactions, thereby altering the molecular weight, hydrodynamic volume and/or isoelectric point of the species of interest and rendering it separable from other component(s) in the mixture.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 3, 2003
    Inventor: Robert Van Reis
  • Patent number: 6509454
    Abstract: The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small molecular weight ligands and the species of interest. The small molecular weight ligands employed in the present invention function to interact with a species of interest in a mixture of different species through either affinity, hydrophobic and/or ionic interactions, thereby altering the molecular weight, hydrodynamic volume and/or isoelectric point of the species of interest and rendering it separable from other component(s) in the mixture.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: January 21, 2003
    Assignee: Genentech, Inc.
    Inventor: Robert Van Reis
  • Patent number: 6077940
    Abstract: The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small molecular weight ligands and the species of interest. The small molecular weight ligands employed in the present invention function to interact with a species of interest in a mixture of different species through either affinity, hydrophobic and/or ionic interactions, thereby altering the molecular weight, hydrodynamic volume and/or isoelectric point of the species of interest and rendering it separable from other component(s) in the mixture.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: June 20, 2000
    Assignee: Genentech, Inc.
    Inventor: Robert Van Reis