Patents by Inventor Robert Van Sluis

Robert Van Sluis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of obtaining extracellular and intracellular pH images and spectra by magnetic resonance using extrinsic indicators containing 1H or 19F
    Patent number: 6596258
    Abstract: The present invention refers to the use of a selection of imidazole compounds in a method of obtaining extracellular or intracellular pH images in biological systems, by magnetic resonance, consisting of administering the imidazole compound to said biological system and acquiring a pH image through magnetic resonance measurements, and said method selected from the group consisting of proton magnetic resonance chemical shift imaging (1H CSI), proton magnetic resonance spectroscopic imaging (1H MRSI), fluorine magnetic resonance chemical shift imaging (19F CSI), fluorine magnetic resonance spectroscopic imaging (19F MRSI), and combinations thereof.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: July 22, 2003
    Assignee: Universidad Nacional de Educacion a Distancia
    Inventors: Paloma Ballesteros García, Ma Soledad Gil González, Paula Zaderenco Partida, Sebastián Cerdán García-Esteller, José Álvarez Pérez, J. Robert Gillies, Raghunand Natarajan, Robert Van Sluis, Zaver Bhujwala