Abstract: The present invention relates to a pen type drug delivery device having a dose setting limiter mechanism. The mechanism comprises a housing (10, 30, 40; 40?), a dose setting member (50), which during dose setting rotates relative to the housing (10, 30, 40; 40?) in a first direction and which during dose dispensing rotates relative to the housing (10, 30, 40; 40?) in a second opposite direction, and a limiting element (60) limiting the rotational movement of the dose setting member between a zero dose position and a maximum dose position. The limiting element (60) is rotationally constrained but axially displaceable relative to one of the housing (10, 30, 40; 40?) or the dose setting member (50) and is movable helically (53) relative to the other of the housing (10, 30, 40; 40?)or the dose setting member (50). These movements have end stops (54, 55) limiting the relative movement of the limiting element (60) and thus the dose setting member.

Abstract: The present invention relates to a drug delivery (5) comprising a housing (10) with a proximal end (28) and a distal end (22), a cartridge holder (14) adapted to retain a cartridge, the cartridge holder (14) being secured to the housing (10) and having an at least partially transparent side wall, and a cap (40) being capable of covering the distal end (22) of the drug delivery device, being rotationally fixed with respect to the housing (10) and comprising a window aperture (44), the window aperture (44) being capable of displaying information revealed by the cartridge holder (14). Furthermore, using a cap (40) for covering the distal end (22) of the drug delivery device (5) is disclosed.

Abstract: An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.

Abstract: The invention refers to an injection device comprising a housing (10) containing a cartridge (20) containing a medicament and a movable bung (21), wherein the housing (10) comprises an inner thread (17), a piston rod (30) for moving the bung (21) during dose dispensing, wherein the piston rod (30) comprises an outer thread (31) engaging the inner thread (17) of the housing (10) a bearing (33) at its end facing the bung (21), and a driver (40) coupled to the piston rod (30) for driving the piston rod (30) during dose dispensing. In the unused delivery state of the device, the bearing (33) abuts the bung (21). The invention further refers to an assembly method for such an injection device.

Abstract: A supplemental device for attachment to an injection device, the supplemental device having a housing containing at least two electromechanical switches each having an open state and a closed state and a protrusion associated with each switch configured to protrude from the housing so as to contact a rotatable surface of the injection device while the supplemental device is attached to the injection device; and a processor arrangement configured to detect a change in the state of each of the switches; and to determine a direction of rotation of the rotatable surface of the injection device from the detected state changes.

Abstract: The piston rod arrangement is in an assembled state before use and comprises a piston rod, a bung, which is intended to be driven by the piston rod, a body member, and a drive member. The piston rod is threadedly engaged with the body member, and the drive member is threadedly engaged with the piston rod and movable relative to the body member. A mechanism is provided defining unit steps of movement of the drive member and corresponding unit steps of movement of the piston rod. The piston rod is arranged in contact with the bung or at a distance from the bung that is less than a distance of one corresponding unit step of movement. When the piston rod, the bung and the drive member are assembled in the body member, the piston rod is advanced with respect to the body member towards the bung, until the piston rod is stopped by the bung. The drive member is rotated until the piston rod begins to advance again and the drive member is then stopped, and the piston rod is fixed at or near the position obtained.

Abstract: The present disclosure concerns an attachment for an operable drug delivery device, comprising a gripping sleeve member that is configured to receive a first member of the operable drug delivery device, wherein the gripping sleeve member comprises a first gripping sleeve member part comprising a first engagement feature at its inner surface that is configured to engage the first gripping sleeve member part in a torque-proof manner with the first member of the operable drug delivery device. Further, the present invention concerns a use of the attachment or a system of attachments for operating the operable drug delivery device.

Abstract: An assembly of a drug delivery device comprises a body (10) having a distal end (11) and a proximal end (12), a drive assembly (4) arranged substantially within the body (10) to facilitate dispense of a medicinal product and a button member (5) arranged at the proximal end (12) of the body (10) and adapted to act upon the drive assembly (4). The drive assembly (4) has an initial pre-ready state, a transient state and a ready state; in the pre-ready and transient states the button member (5) is twistable with respect to the body (10) to act upon the drive assembly (4) and wherein in the ready state the button member (5) is axially moveable but not substantially twistable with respect to the body (10) to act upon the drive assembly (4) to dispense a dose of the medicinal product.

Abstract: A resettable drive assembly for a drug delivery device (1) is provided. The drive assembly comprises a drive unit (3) for driving a piston rod (5) in a dispense operation of the device (1). The drive unit (3) comprises a first drive member (35), a second drive member (37) and locking means preventing a relative rotational movement of the first (35) and the second drive member (37) during a dispense operation and allowing a relative rotational movement for enabling a resetting of the device (1). Moreover, a drug delivery device (1) comprising a resettable drive assembly is provided.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: The present disclosure relates to a resettable drive mechanism for use in a drug delivery device. The drug delivery device is having a distal direction and a proximal direction. The drive mechanism comprises a drive rack engaged with a drive gear, a piston rack engaged with a piston gear and coupling means for coupling the drive gear with the piston gear. In a first state of the drive mechanism, the drive gear and the piston gear are coupled and the piston rack moves in distal direction when the drive rack is moved in distal direction. In a second state of the drive mechanism, the drive gear and the piston gear are decoupled and the piston rack is moveable in proximal direction for resetting the drive mechanism.

Abstract: The present invention relates to a method for the assembly of drug delivery devices, in particular of pen-type drug delivery devices, having a dose dial mechanism and a drive mechanism, enabling the administration of medicinal products from a multidose cartridge and the drug delivery devices obtainable according to the said method.

Abstract: A lead screw (5) with a screw thread (6) is arranged in a body (1) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: A drug delivery device comprising: a device body, an operating member which is configured to be movable relative to the device body for operating the drug delivery device, a preventing member which prevents movement of the operating member relative to the device body for operating the drug delivery device, wherein the preventing member is removable to allow movement of the operating member relative to the device body for operating the drug delivery device.

Abstract: Generally disclosed is an adhesively secured seal and related methods for sealing a hopper car hatch without the risk of contaminating the hopper car load with food-grade adhesive and without damaging the hopper car or requiring excessive cleaning when removed. The disclosed seal comprises a piece or sheet of plastic with self-contained food-grade adhesive. Preferably, the plastic is cut to fit the length of the hatch of a rail car and features food-grade adhesive along on its surface its edges. In another embodiment, the apparatus is rolled, like tape, wherein the apparatus is installed over a hatch opening so that the sides of the apparatus containing food-grade adhesive are contacted with the rim and sides of the hatch.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: A drug delivery device comprises a first component and a second component, wherein a substance is provided on at least one of the first component and the second component. An inner friction of the substance is great enough to stabilize at least one of the orientation and the position of the first component and the second component with respect to one another. The inner friction of the substance is small enough to allow relative movement of the first component and the second component necessary for the intended operation of the device. Furthermore, a method for assembling a drug delivery device is provided.

Abstract: A medication delivery device (1) comprises a housing (4) having a proximal end (P) and a distal end (D), a cartridge (3) for holding a medication (M), the cartridge (3) having an outlet (2), a moveable piston (5) being retained within the cartridge (3), a drive member (17) moveable in a proximal direction with respect to the housing (4) for setting a dose of medication (M) to be delivered and in the distal direction with respect to the housing (4) for delivering the dose and a piston rod (10) adapted to drive the piston (5) in a distal direction with respect to the cartridge (3) for delivering the dose. The drive member (17) is releasably coupled to the piston rod (10). The medication delivery device (1) further comprises a resilient member (21) which is arranged to move the drive member (17) in the proximal direction with respect to the housing (4) after dose delivery, thereby reducing pressure of the piston rod (10) on the piston (5).