Patents by Inventor Robert Vince

Robert Vince has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sunless tanning compounds and compositions
    Patent number: 9987211
    Abstract: The invention provides sunless tanning compositions comprising a compounds of formula (I): or a salt thereof as described herein as well as methods for tanning mammalian skin by contacting the skin with the compounds of formula (I) or compositions comprising compounds of formula (I).
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: June 5, 2018
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • Therapeutic formulations and methods
    Patent number: 9757354
    Abstract: The invention provides compositions and methods for treating cyanide poisoning.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: September 12, 2017
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Steven Earl Patterson, Herbert Tsukasa Nagasawa, Robert Vince, Alexandre Monteil
  • HYPERSPECTRAL IMAGING FOR DETECTION OF PARKINSON'S DISEASE
    Publication number: 20170172410
    Abstract: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Parkinson's disease (PD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against PD.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 22, 2017
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Swati Sudhakar More
  • Hyperspectral imaging for early detection of Alzheimer'S Disease
    Patent number: 9585558
    Abstract: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Alzheimer's disease (AD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against AD.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: March 7, 2017
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Swati Sudhakar More
  • SUNLESS TANNING COMPOUNDS AND COMPOSITIONS
    Publication number: 20170000712
    Abstract: The invention provides sunless tanning compositions comprising a compounds of formula (I): or a salt thereof as described herein as well as methods for tanning mammalian skin by contacting the skin with the compounds of formula (I) or compositions comprising compounds of formula (I).
    Type: Application
    Filed: July 2, 2014
    Publication date: January 5, 2017
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • THERAPEUTIC FORMULATIONS AND METHODS
    Publication number: 20160354341
    Abstract: The invention provides compositions and methods for treating cyanide poisoning.
    Type: Application
    Filed: June 8, 2016
    Publication date: December 8, 2016
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Steven Earl Patterson, Herbert Tsukasa Nagasawa, Robert Vince, Alexandre Monteil
  • Agents that prevent or repair skin damage
    Patent number: 9403778
    Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: August 2, 2016
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • Glutathione analogs and uses thereof
    Patent number: 9394338
    Abstract: The invention provides compounds of formula (I): (I) or salts thereof, wherein R1, R2, R3 Z, and X have any of the values defined herein, as well as compositions comprising such compounds. The compounds and compositions are useful for treating neurodegenerative disorders.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: July 19, 2016
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Swati Sudhakar More
  • Open chained or fused 1,1?-alkylene-bis-uracil derivatives, useful in skin UV-protection
    Patent number: 9364406
    Abstract: The invention provides compounds of formula I; or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: June 14, 2016
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • Method for preparation of 5-substituted pyrimidines
    Patent number: 9169216
    Abstract: The present invention provides a method to prepare 5-substituted pyrimidines by reacting a 5-acylpyrimidine with a suitable nucleophile to afford a 5-methanolpyrimidine, such as flurprimidol.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: October 27, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Ashish P. Vartak
  • OPEN CHAINED OR FUSED 1,1 '-ALKYLENE-BIS-URACIL DERIVATIVES, USEFUL IN SKIN UV-PROTECTION
    Publication number: 20150231051
    Abstract: The invention provides compounds of formula I; or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
    Type: Application
    Filed: October 11, 2013
    Publication date: August 20, 2015
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • AGENTS THAT PREVENT OR REPAIR SKIN DAMAGE
    Publication number: 20140350036
    Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
    Type: Application
    Filed: January 11, 2013
    Publication date: November 27, 2014
    Inventors: Robert Vince, Abbas Raza, Christine Dreis
  • HYPERSPECTRAL IMAGING FOR EARLY DETECTION OF ALZHEIMER'S DISEASE
    Publication number: 20140348750
    Abstract: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Alzheimer's disease (AD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against AD.
    Type: Application
    Filed: December 10, 2012
    Publication date: November 27, 2014
    Inventors: Robert Vince, Swati Sudhakar More
  • GLUTATHIONE ANALOGS AND USES THEREOF
    Publication number: 20140154192
    Abstract: The invention provides compounds of formula (I): (I) or salts thereof, wherein R1, R2, R3 Z, and X have any of the values defined herein, as well as compositions comprising such compounds. The compounds and compositions are useful for treating neurodegenerative disorders.
    Type: Application
    Filed: July 6, 2012
    Publication date: June 5, 2014
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Robert Vince, Swati Sudhakar More
  • METHOD FOR PREPARATION OF 5-SUBSTITUTED PYRIMIDINES
    Publication number: 20140121375
    Abstract: The present invention provides a method to prepare 5-substituted pyrimidines by reacting a 5-acylpyrimidine with a suitable nucleophile to afford a 5-methanolpyrimidine, such as flurprimidol.
    Type: Application
    Filed: March 8, 2012
    Publication date: May 1, 2014
    Applicant: Regents of the University of Minnesota
    Inventors: Robert Vince, Ashish P. Vartak
  • THERAPEUTIC METHODS, COMPOSITIONS, AND COMPOUNDS
    Publication number: 20120329731
    Abstract: In one embodiment the invention provides a method of combating cyanide poisoning, which comprises administering to a subject a compound capable of releasing 3-mercapto-pyruvate in vivo. In other embodiments the invention also provides pharmaceutical compositions comprising a compound capable of releasing 3-mercaptopyruvate in vivo, as well as novel compounds that are capable of releasing 3-mercaptopyruvate in vivo.
    Type: Application
    Filed: October 13, 2011
    Publication date: December 27, 2012
    Inventors: Herbert T. Nagasawa, David J.W. Goon, Daune L. Crankshaw, Robert Vince
  • THERAPEUTIC METHODS, COMPOSITIONS AND COMPOUNDS
    Publication number: 20090197865
    Abstract: In one embodiment the invention provides a method of combating cyanide poisoning, which comprises administering to a subject a compound capable of releasing 3-mercapto-pyruvate in vivo. In other embodiments the invention also provides pharmaceutical compositions comprising a compound capable of releasing 3-mercaptopyruvate in vivo, as well as novel compounds that are capable of releasing 3-mercaptopyruvate in vivo.
    Type: Application
    Filed: June 28, 2007
    Publication date: August 6, 2009
    Inventors: Herbert T. Nagasawa, David J.W. Goon, Daune L. Crankshaw, Robert Vince
  • Dideoxycarbocyclic nucleosides
    Patent number: 6534512
    Abstract: A therapeutic method is provided, employing an antiviral compound of the general formula: wherein Z is HI OR′ or N(R)2, wherein R′ is H, (C1-C4)alkyl, aryl, CHO, (C1-C16)alkanoyl or O═P(OH)2, Y is CH or N, and X is selected from the group consisting of H, N(R)2, SR, OR′ or halogens wherein R is H, lower(C1-C4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: March 18, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Mei Hua
  • Dideoxycarbocyclic nucleosides
    Patent number: 6072053
    Abstract: A therapeutic method is provided, employing an antiviral compound of the general formula: ##STR1## wherein Z is H, OR' or N(R).sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R).sub.2, SR, OR' or halogen, wherein R is H, lower (C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: June 6, 2000
    Inventors: Robert Vince, Mei Hua
  • Method of preparation of dideoxycarbocyclic nucleosides
    Patent number: 5962684
    Abstract: A therapeutic method is provided, employing an antiviral compound of the general formula: ##STR1## wherein Z is H, OR' or N(R).sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R).sub.2, SR, OR' or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: October 5, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Mei Hua