Abstract: A propeller according to an embodiment includes a hub and a series of blades extending outward from the hub. Each blade of the series of blades includes a core and a skin covering the core. The core may be formed of a ceramic first material and the skin is formed of a second material different than the ceramic first material. The ceramic first material of the core may be ceramic Si3N4 (silicon nitride), yttria-toughened zirconia ceramic, or alumina-zirconia ceramic, and the second material of the skin may be a polymer. The polymer skin is configured to function as a shock absorber protecting the ceramic core, and the ceramic core is configured to provide rigidity to maintain the shape of the propeller blades under aerodynamic loading, which enables improved aerodynamic efficiency and reduced noise generation.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: A snack bottle with distensible dispensing cap that includes a deformable container portion attachable to a rubberlike dispensing cap, said dispensing cap having a slit opening rendered linearly therein, wherein deformation of the container portion by application of manual pressure thereto distends the slit opening in the dispensing cap, and snacks additional to the container portion are transmissible through the dispensing cap when the slit opening is distended, whereby snacks storable within the container portion are dispensable singlehandedly from said container portion.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: Compositions, equipment, and methods for prognosing, diagnosing, preventing, or treating colon cancer. Colon cancer genes that are differentially expressed in colon cancer tissues relative to disease-free tissues are identified. Examples of these genes are illustrated in Tables 1-5. Colon cancer genes of the present invention and their encoded products can be used as markers or prophylactic or therapeutic agents for the detection or treatment of colon cancer.