Patents by Inventor Robert Volkmann

Robert Volkmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NMDA receptor modulators and uses thereof
    Patent number: 11807650
    Abstract: Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated to modulate the NMDA receptor.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: November 7, 2023
    Assignee: Novartis AG
    Inventors: David R. Anderson, Robert Volkmann, Frank Menniti, Christopher Fanger, Yuelian Xu
  • OXABICYCLOHEPTANE PRODRUGS
    Publication number: 20220235066
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: January 27, 2022
    Publication date: July 28, 2022
    Inventors: John S. KOVACH, Robert VOLKMANN, Anthony MARFAT
  • NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20220153755
    Abstract: Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated to modulate the NMDA receptor.
    Type: Application
    Filed: January 27, 2022
    Publication date: May 19, 2022
    Inventors: David R. Anderson, Robert Volkmann, Frank Menniti, Christopher Fanger, Yuelian Xu
  • Oxabicycloheptane prodrugs
    Patent number: 11236102
    Abstract: The present invention provides a compound having the structure:
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: February 1, 2022
    Assignee: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • OXABICYCLOHEPTANE PRODRUGS
    Publication number: 20200325151
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: February 5, 2020
    Publication date: October 15, 2020
    Inventors: John S. KOVACH, Robert VOLKMANN, Anthony MARFAT
  • Oxabicycloheptane prodrugs
    Patent number: 10618908
    Abstract: The present invention provides a compound having the structure:
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: April 14, 2020
    Assignee: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • OXABICYCLOHEPTANE PRODRUGS
    Publication number: 20190359627
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: June 12, 2019
    Publication date: November 28, 2019
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • Octahydrocyclopenta[c]pyrrole allosteric inhibitors of SHP2
    Patent number: 10435389
    Abstract: The present invention relates to compounds capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds, and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: October 8, 2019
    Assignee: Krouzon Pharmaccuticals, Inc.
    Inventors: Robert Volkmann, Anthony Marfat, Frederick Nelson, Panayiotis Zagouras
  • Oxabicycloheptane prodrugs
    Patent number: 10364252
    Abstract: The present invention provides a compound having the structure:
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: July 30, 2019
    Assignee: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • Octahydrocyclopenta[c]pyrrole Allosteric Inhibitors of SHP2
    Publication number: 20190077792
    Abstract: The present invention relates to compounds capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds, and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: September 11, 2018
    Publication date: March 14, 2019
    Inventors: Robert Volkmann, Anthony Marfat, Frederick Nelson, Panayiotis Zagouras
  • COMPOUNDS FOR TREATMENT OF PAIN
    Publication number: 20190002473
    Abstract: The aspects of the disclosed embodiments are directed to novel compounds, formulations containing said compounds or pharmaceutically acceptable salts thereof which are suitable for administration to a patient.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Robert Volkmann, Anthony Marfat, Peter Cornelius, Panayiotis Zagouras, Fredrick Raymond Nelson, Anton Franz Joseph Fliri
  • Compounds for treatment of pain
    Patent number: 10072018
    Abstract: The aspects of the disclosed embodiments are directed to novel compounds, specifically, quaternary ammonium derivatives of tertiary amine containing opioid drug compounds such as hydrocodone, hydromorphone and oxycodone, formulations containing said. compounds or pharmaceutically acceptable salts thereof, which are capable of providing controlled release of the opioid drug upon administration to a patient in order to treat pain.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 11, 2018
    Assignee: BIOPHARMA WORKS
    Inventors: Robert Volkmann, Anthony Marfat, Peter Cornelius, Panayiotis Zagouras, Fredrick Raymond Nelson, Anton Franz Joseph Fliri
  • OXABICYCLOHEPTANE PRODRUGS
    Publication number: 20180244690
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: May 1, 2018
    Publication date: August 30, 2018
    Applicant: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • Oxabicycloheptane prodrugs
    Patent number: 9988394
    Abstract: The present invention provides a compound having the structure:
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: June 5, 2018
    Assignee: Lixte Biotechnology Inc.
    Inventors: John S. Kovach, Robert Volkmann, Anthony Marfat
  • OXABICYCLOHEPTANE PRODRUGS
    Publication number: 20160333024
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: May 13, 2016
    Publication date: November 17, 2016
    Applicant: Lixte Biotechnology, Inc.
    Inventors: JOHN S. KOVACH, ROBERT VOLKMANN, ANTHONY MARFAT
  • Compounds for treatment of pain
    Patent number: 9487531
    Abstract: The invention is directed to novel compounds, formulations containing said compounds or pharmaceutically acceptable salts thereof which are suitable for administration to a patient.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: November 8, 2016
    Assignee: BioPharma Works LLC
    Inventors: Robert Volkmann, Anthony Marfat, Peter Cornelius, Panayiotis Zagouras, Frederick Raymond Nelson, Anton Franz Joseph Fliri
  • COMPOUNDS FOR TREATMENT OF PAIN
    Publication number: 20160083393
    Abstract: The aspects of the disclosed embodiments are directed to novel compounds, specifically, quaternary ammonium derivatives of tertiary amine containing opioid drug compounds such as hydrocodone, hydromorphone and oxycodone, formulations containing said. compounds or pharmaceutically acceptable salts thereof, which are capable of providing controlled release of the opioid drug upon administration to a patient in order to treat pain.
    Type: Application
    Filed: April 16, 2014
    Publication date: March 24, 2016
    Inventor: Robert VOLKMANN
  • COMPOUNDS FOR TREATMENT OF PAIN
    Publication number: 20160068537
    Abstract: The invention is directed to novel compounds, formulations containing said compounds or pharmaceutically acceptable salts thereof which are suitable for administration to a patient.
    Type: Application
    Filed: April 16, 2014
    Publication date: March 10, 2016
    Inventors: Robert Volkmann, Anthony Marfat, Peter Cornelius, Panayiotis Zagouras, Frederick Raymond Nelson, Anton Franz Joseph Fliri
  • 5-METHYLDIHYDROMORPHONE COMPOUNDS FOR TREATMENT OF PAIN
    Publication number: 20140323416
    Abstract: The aspects of the present disclosure are directed to novel compounds, formulations containing said compounds or pharmaceutically acceptable salts thereof which are suitable for administration to a patient. In particular, to 5-methyldihydromorphone prodrug compounds described in general Formula I and II and the use of the compounds for treating pain associated with a variety of chronic human disorders including for example neuropathic pain and pain associated with cancer, surgeries or injuries.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 30, 2014
    Inventors: Anthony MARFAT, Peter CORNELIUS, Robert VOLKMANN, Panayiotis ZAGOURAS, Frederick Raymond NELSON, Anton Franz Joseph FLIRI
  • Pharmaceutical compositions comprising a NOS inhibitor
    Publication number: 20060058267
    Abstract: This invention relates to methods of treating neurodegenerative diseases and inhibiting neurological damage, comprising administering to a patient in need of such treatment an N-NOS inhibitor in combination with a GABA-A receptor modulator.
    Type: Application
    Filed: October 25, 2005
    Publication date: March 16, 2006
    Inventors: John Lowe, Robert Volkmann