Abstract: A device that can hold at least two cans of spray paint or chalk, thus enabling marking with different colors using a single device. The device comprises a staff, a can holster, a grip, a trigger and a selector. The selector comprises a selector rod moveable in or alongside the staff. At one end of the selector rod is a selector knob and at the other is an engagement mechanism that engages the spray valve of each can, one can at a time. The engagement mechanism comprises a cam and a rocker arm with two opposing fingers, one to engage each spray can when selected. Optionally one or more flag holders may be attached to the staff for holding marker flags.

Abstract: A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of Formula 1.0: to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Novel compounds of the formulas 5.0, 5.1 and 5.2, wherein R is —C(R20)(R21)(R46), and 5.3, 5.3A and 5.3B, wherein R is —N(R25)(R48), are disclosed. Also disclosed are processes for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3. Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.

Abstract: A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of Formula 1.0 ##STR1## Also disclosed are novel compounds of the formulas: ##STR2## Also disclosed are processes for making 3-substituted compounds of the Formulas 1.1, 1.2 and 1.3.Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formulas 1.1, 1.2, and 1.3.