Patents by Inventor Robert W. Chestnut

Robert W. Chestnut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for eliciting CTL immunity
    Patent number: 6419931
    Abstract: Cytotoxic T lymphocyte responses are effectively induced to an antigen of interest, particularly viral, bacterial, parasitic and tumor antigens. Compositions, including pharmaceutical compositions, of CTL-inducing peptide and an adjuvant or a lipidated peptide which induces a helper T cell (HTL) response stimulate the antigen specific CTL response. Among the viral antigens to which the CTL responses are effectively induced in humans are those of hepatitis B. The CTL response may be optimized by a regimen of two or more booster administrations. Cocktails of two or more CTL inducing peptides are employed to optimize epitope and/or MHC class I restricted coverage.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: July 16, 2002
    Assignee: Epimmune Inc.
    Inventors: Maria A. Vitiello, Robert W. Chestnut, Alessandro D. Sette, Esteban Celis, Howard Grey
  • Antibodies to P-selectin and their uses
    Patent number: 5800815
    Abstract: The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: September 1, 1998
    Assignee: Cytel Corporation
    Inventors: Robert W. Chestnut, Margaret J. Polley, James C. Paulson, S. Tarran Jones, Jose W. Saldanha, Mary M. Bendig, Michael Kriegler, Carl Perez, Robert Bayer, Michael Nunn