Abstract: Described herein are tricyclic PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.

Abstract: Described herein are PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.

Abstract: Implantable medical systems enter an exposure mode of operation, either manually via a down linked programming instruction or by automatic detection by the implantable system of exposure to a magnetic disturbance. A controller then determines the appropriate exposure mode by considering various pieces of information including the device type including whether the device has defibrillation capability, pre-exposure mode of therapy including which chambers have been paced, and pre-exposure cardiac activity that is either intrinsic or paced rates. Additional considerations may include determining whether a sensed rate during the exposure mode is physiologic or artificially produced by the magnetic disturbance. When the sensed rate is physiologic, then the controller uses the sensed rate to trigger pacing and otherwise uses asynchronous pacing at a fixed rate.

Abstract: A photoresist-type chemical etching process is used to define a computer-generated flat pattern of conductors as if a complex conical spiral had been cut apart along a straight line through the apex and laid flat. The substrate in the shape of a circular sector is bent into a cone and the radial edges are joined in a seam. The split turns of the spiral are electrically interconnected across the seam.

Abstract: A computerized transceiver repeatedly sweeps through a set of transmit/receive frequencies to interrogate collectively a plurality of groups of items in a stocking area. Items in each group are tagged with a printed circuit transponder tuned to frequencies uniquely assigned to each group. Data returned is stored and combined mathematically by the computer to arrive at the total number of items in each group. The system is particularly adapted for taking inventory of a large number of retail shelf goods using a mobile transceiver.

Abstract: A photoresist-type chemical etching process is used to define a computer-generated flat pattern of conductors as if a complex conical spiral had been cut apart along a straight line through the apex and laid flat. The substrate in the shape of a circular sector is bent into a cone and the radial edges are joined in a seam. The split turns of the spiral are electrically interconnected across the seam.

Abstract: A computerized transceiver repeatedly sweeps through a set of transmit/receive frequencies to interrogate collectively a plurality of groups of items in a stocking area. Items in each group are tagged with a printed circuit transponder tuned to frequencies uniquely assigned to each group. Data turned is stored and combined mathematically by the computer to arrive at the total number of items in each group. The system is particularly adapted for taking inventory of a large number of retail shelf goods using a mobile transceiver.

Abstract: The inside surface of a conductive vessel (preferably spherical) with insulated adjacent segments is coated with a dielectric layer. The vessel is then partly filled with a conductive liquid-like material such as mercury having an upper surface which remains approximately horizontal irrespective of the inclination of the vessel. The capacitance between the segments and liquid varies as a function of the vessel's inclination. Vibration-induced surface action also produces varying capacitance which can be detected for seismometer applications and the like.

Abstract: Apparatus for processing a polychromatic optical beam for display on a color television receiver employs an optical splitter that divides an incident beam into a sub-beam responsive to luminance and into two single-color sub-beams. The splitter employs a beam splitting element, a reflective filter, and an absorbent filter. Converter elements convert the three sub-beams into corresponding electrical signals, and electronic circuits combine them to produce a composite signal having the format of chrominance and of luminance signal components standard for color television display.A consumer product for the home display of motion pictures on a color television receiver advantageously employs the foregoing construction.