Abstract: Aspects of the present disclosure relate generally to preparing models of three-dimensional structures. In particular, a model of a three-dimensional structure constructed of porous geometries is prepared. A component file including a porous CAD volume having a boundary is prepared. A space including the porous CAD volume is populated with unit cells. The unit cells are populated with porous geometries having a plurality of struts having nodes on each end. The space is populated with at least one elongated fixation element extending beyond the boundary to produce an interlocking feature enabling assembly or engagement with a mating structure.

Abstract: Aspects of the present disclosure relate generally to preparing models of three-dimensional structures. In particular, a model of a three-dimensional structure constructed of porous geometries is prepared. A component file including a porous CAD volume having a boundary is prepared. A space including the porous CAD volume is populated with unit cells. The unit cells are populated with porous geometries having a plurality of struts having nodes on each end. The space is populated with at least one elongated fixation element extending beyond the boundary to produce an interlocking feature enabling assembly or engagement with a mating structure.

Abstract: One embodiment of the implant comprises a porous metal bone ingrowth portion (14) having a first side connected to a high density or solid (fully dense) metal portion (16) which in turn has an opposite side connected to a porous metal soft tissue ingrowth portion (12) thus forming a sandwich structure with the high density or fully dense portion in the middle. The implant may be made of a resorbable material such as an alloy of magnesium. Alternately, the alloy can be selected from the group consisting of calcium, iron, yttrium and lithium. The porous metal soft tissue ingrowth portion (12) has porosity characteristics allowing cartilage to interdigitate with the pores and extend outwardly beyond the platform of the metal surface towards a joint capsule. The solid or fully dense intermediate layer 16 may have some porosity, however that porosity prevents either bone tissue or cartilage tissue from migrating therethrough.

Abstract: A temporary femoral implant system has a porous mold and a femoral component. The system fits at least partially in a femoral cavity. The mold has a wall with an interior surface and an exterior surface forming an interior space for receiving an antibiotic bone cement. The mold allows the antibiotic to diffuse through the wall to the exterior surface. The femoral component has a stem portion received within the mold. A method of using the implant system includes providing an implant system comprising a mold and a femoral component, inserting the mold into the femoral cavity with the exterior surface facing the femoral cavity, inserting the stem portion of a femoral component into the interior space of the mold and filling the interior space of the mold with an antibiotic bone cement.

Abstract: In one embodiment, the present invention may be a method of forming a porous and/or dense article from metal powder (12), including adding to a mold a first feedstock comprising an agglomerated metal powder (12) and an agglomeration agent, forming said first feedstock into a green state dense article (22); and removing said agglomeration agent. Furthermore, the present invention may include a second feedstock including an agglomerated metal powder (12), a space filling material and an agglomeration agent which may be formed into a green state porous article (21). The present invention also includes a dense and/or porous article (22 and 21) manufactured by various methods, as well as methods for creating the dense and porous feedstocks. Moreover, the present invention may include an article which may be a medical implant.

Abstract: A temporary femoral implant system has a porous mold and a femoral component. The system fits at least partially in a femoral cavity. The mold has a wall with an interior surface and an exterior surface forming an interior space for receiving an antibiotic bone cement. The mold allows the antibiotic to diffuse through the wall to the exterior surface. The femoral component has a stem portion received within the mold. A method of using the implant system includes providing an implant system comprising a mold and a femoral component, inserting the mold into the femoral cavity with the exterior surface facing the femoral cavity, inserting the stem portion of a femoral component into the interior space of the mold and filling the interior space of the mold with an antibiotic bone cement.

Abstract: Compositions and methods for the treatment of acne including a peroxide and an antibiotic from the lincomycin family of antibiotics are disclosed.

Abstract: The present invention provides a method for applying a plurality, preferably two, of dermatological agents to the skin from a single dispensing and applicator sheet comprising a plurality of discrete areas comprising at least two dermatological agents which are simultaneously released from the sheet and applied to the afflicted skin area when the sheet is rubbed over wet skin.

Abstract: Compositions for treating acne that contain a peroxide and an antibiotic selected from the lincomycin family are disclosed. In particular, compositions containing benzoyl peroxide and clindamycin are disclosed along with methods of treating acne using these compositions.

Abstract: Composition and method for the treatment of acne including a peroxide and an antibiotic selected from the lincomycin family of antibiotics.

Abstract: Strake, flap and canard control surfaces of an aircraft are driven by an error signal which is comprised of a pilot stick command signal and feedback components including measured vertical acceleration and pitch rate of the aircraft and a third feedback component derived from a complementary filter. The filter has a high-pass filter section which operates upon canard position data and a low-pass filter section which operates upon pitch rate. A summation of the signals passing both filtering sections is summed with the vertical acceleration and pitch rate feedback signals to form a combined feedback signal.

Abstract: Process and composition for the topical treatment of acne which comprises as ingredients a peroxide of an organic acid and an erythromycin compound selected from the group consisting of erythromycin and its stearate and glucoheptonate derivatives and in which said peroxide is from one-half to thirty times, the weight of said erythromycin compound, and a suitable pharmaceutically acceptable carrier.

Abstract: Process and composition for the topical treatment of acne which comprises as ingredients a peroxide of an organic acid and an erythromycin compound selected from the group consisting of erythromycin and its stearate and glucoheptonate derivatives and in which said peroxide is from one-half to thirty times, the weight of said erythromycin compound, and a suitable pharmaceutically acceptable carrier.

Abstract: A spreadable, flowable and greaseless cosmetic coverup composition which includes a relatively large amount of pigment and a mixture of two alkoxylated surfactants.

Abstract: A method of treating skin conditions utilizing a deodorized composition containing soluble polysulfide compounds and the composition therefor.

Abstract: Aqueous benzoyl compositions peroxide stabilized with dioctyl sodium sulfosuccinate for treating mammals.

Abstract: This present invention relates to a solution for topical or local application comprising at least one corticosteroid; from about 1% to 4% by weight of solubilization agents consisting essentially of a combination of at least one glyceryl ester of a fatty acid of 6 to 22 carbon atoms and a betaine surfactant, from about 10% to 50% by weight of composition of an alkanol cosolvent, and from about 20% to 50% water.

Abstract: Compositions effective for topically treating skin conditions, especially psoriasis and eczema which contains as an essential ingredient coal tar in a gel base.

Abstract: The present invention relates to a novel synergistic composition and to a method of treating inflammation in warm blooded animals by topically administering to a warm blooded animal in need of such treatment an effective amount of the synergistic combination of a non-steroidal agent having anti-inflammatory activity and bis-(2-pyridyl-1-oxide) disulfide and/or at least one adduct of bis-(2-pyridyl-1-oxide) disulfide having the empirical formula:(C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t (I)wherein M represents a member selected from the group consisting of zinc, iron, magnesium, tin, cadmium, zirconium, alkali and alkaline earth metals; Y is the anion of an inorganic acid and t is either 1 or 2.

Abstract: The present invention relates to a method of topically treating inflammation in warm blooded animals which comprises administering to a warm blooded animal in need of such treatment an effective amount of bis-(2-pyridyl-1-oxide) disulfide and/or the adducts of bis-(2-pyridyl-1-oxide) disulfide having the empirical formula:(C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t (I)wherein M represents a member selected from the group consisting of zinc, iron, magnesium, tin, cadmium, zirconium, alkali and alkaline earth metals; Y is the anion of an inorganic or organic acid and t is either 1 or 2.