Abstract: The present invention provides a method of attenuating the formation or reducing the severity of neurogenic pain in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic pain.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of swelling and/or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of swelling and/or inflammation.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of a bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of neurogenic swelling and/or neurogenic inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic swelling and/or neurogenic inflammation.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of neurogenic swelling and/or neurogenic inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic swelling and/or neurogenic inflammation.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of a neurogenic bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of a bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.

Abstract: The present invention provides a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to a portion of the surface of the skin of the patient in an amount and at a location sufficient to attenuate swelling or inflammation.

Abstract: The invention provides a wound dressing comprising a body and a polymeric film adhered to at least a portion of the body. The body comprises a flexible, porous polyurethane-based foam and a liquid absorbing component. The invention further provides a wound dressing comprising a first body, a second body, and at least one polymeric film disposed between the first and second bodies. The invention additionally provides methods for treating an injury to a patient's nasal passages utilizing a wound dressing according to the invention.

Abstract: Wound packing material comprising a resilient polymer-based foam sheet of a predetermined thickness. The foam sheet includes at least one slit of a predetermined length that extends from the foam surface into the foam to a predetermined depth. This slit, or slits, permits the foam, when folded upon itself, to occupy a smaller volume than the foam would occupy when folded over upon itself in the same manner, but in the absence of the slit.

Abstract: Wound dressing for a nasal cavity comprising a flexible, porous polyurethane-based foam comprising a liquid-absorbing component, wherein the dressing is provided in a in a shape acceptable for insertion into a nasal cavity, e.g., cylindrical, conical or frustro-conical shape.

Abstract: The present invention provides a method of attenuating the formation or reducing the severity of a bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.

Abstract: The present invention provides a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to a portion of the surface of the skin of the patient in an amount and at a location sufficient to attenuate swelling or inflammation.

Abstract: The present invention provides a method of attenuating the response of nociceptors to noxious stimuli by applying a composition comprising a hydrophilic foam substrate, a polymeric hydrophilic agent capable of absorbing water to the surface of the skin. In other aspects, the present invention provides a method of preventing the formation of a bruise in traumatized tissue, a method of attenuating swelling, a method of attenuating neurogenic inflammatory response, and a method of reducing the sensation of pain by applying like compositions to the surface of the skin of patients.

Abstract: The present invention provides a method of attenuating the formation of a bruise and a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to the surface of the skin.

Abstract: Tamper-evident packaging for a product, e.g., a wound dressing or other sterile medical device. The packaging comprises a top sheet and a bottom sheet, the top sheet sealed to the bottom sheet about the product so as to seal the product between the top and bottom sheets, wherein the portion of the top and bottom sheets that are sealed to each other define sealing areas. The top sheet has at least one perforation in its sealing area so that when the sheets are separated from one another, the top sheet tears adjacent to the at least one perforation, indicating that the package has been at least partially opened.

Abstract: A non-stretchable wound dressing has a flexible, non-stretching cover sheet having adhesive on one side thereof, and having two spaced strip-form gripping tabs at opposite ends thereof. The cover sheet covers a urethane wound dressing with the adhesive of the cover sheet being in contact with the urethane, and the urethane having an adhesive layer on an opposite side thereof. For storage and prior to application to a patient, the adhesive of the urethane wound dressing is in contact with a releasable surface of a carrier, such as cardboard. For application to a patient, one of the cover sheet gripping tabs is pulled so as to release the cover sheet and wound dressing from the carrier, the cover sheet preventing stretching of the wound dressing. The combination is then applied to a patient, again the cover sheet preventing stretching of the wound dressing.

Abstract: A non-stretching wound dressing is provided for use with a patient. The wound dressing includes a cover sheet having top and bottom sides, a thin film sheet formed on the bottom side of the cover sheet, the film sheet having first and second ends and an adhesive side, and a carrier sheet in adjacent contact with the adhesive side of the thin film sheet. The dressing also includes a first gripping tab attached to one end of the thin film sheet and disposed between the film sheet and the carrier sheet for separating the carrier sheet from the film sheet with the cover sheet remaining affixed to the film sheet. A second gripping tab is attached to the top side of the cover sheet and at one end of the cover sheet so that pulling on the second gripping tab releases the cover sheet from the film sheet with the film sheet remaining in place on the patient.

Abstract: Wound packing material comprising a resilient polymer-based foam sheet of a predetermined thickness. The foam sheet includes at least one slit of a predetermined length that extends from the foam surface into the foam to a predetermined depth. This slit, or slits, permits the foam, when folded upon itself, to occupy a smaller volume than the foam would occupy when folded over upon itself in the same manner, but in the absence of the slit.

Abstract: The present invention provides a method of attenuating the formation of a bruise and a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to the surface of the skin.