Patents by Inventor Robert W. Vaughan

Robert W. Vaughan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8088586
    Abstract: The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC molecules to which antibodies to said recombinant MHC molecules contained within the sample have bound. This method allows the depletion of one or more specific MHC particularly HLA allele antibodies from a sample.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: January 3, 2012
    Assignees: Oxford Radcliffe Hospital NHS Trust, Guy's & St. Thomas' Hospital NHS Trust, King's College London
    Inventors: Martin C. N. M. Barnardo, Andrea W. Harmer, Michael Bunce, Robert W. Vaughan, Kenneth I. Welsh
  • Publication number: 20040191245
    Abstract: The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC molecules to which antibodies to said recombinant MHC molecules contained within the sample have bound. This method allows the depletion of one or more specific MHC particularly HLA allele antibodies from a sample.
    Type: Application
    Filed: July 22, 2003
    Publication date: September 30, 2004
    Inventors: Martin C. M. M. Barnardo, Andrea W. Harmer, Michael Bunce, Robert W. Vaughan, Kenneth I. Welsh
  • Patent number: 4265350
    Abstract: A clutch for engaging and disengaging rotary systems and devices such as alternators and generators, which includes a hollow engaging knob fitted with projecting engaging pins, a spindle shaft and plate mounted on a rotating shaft and cooperating with the engaging knob and engaging pins, and a drive pulley rotatably positioned on the rotating shaft and having seats for selective registration with the engaging pins. A spring is positioned in the hollow cavity of the engaging knob to facilitate biasing of the engaging pins through apertures in the spindle plate and in registration with the seats in the drive pulley when the clutch is engaged. Retraction of the engaging knob and engaging pins against the bias of the spring facilitates retraction of the pins from the pulley seats, and effects disengagement of the clutch and free rotation of the drive pulley.
    Type: Grant
    Filed: April 26, 1979
    Date of Patent: May 5, 1981
    Inventor: Robert W. Vaughan
  • Patent number: 4229550
    Abstract: Vinyl polybutadiene maleimide prepolymers which are peroxide curable are provided. The prepolymers are formed from the reaction product of a vinyl polybutadiene providing pendant vinyl groups and a maleimide and, more particularly, a mixture of aliphatic maleimides with cycloaliphatic or aromatic maleimides in combination with a peroxide-free radical initiator. The prepolymer is a vinyl polybutadiene backbone structure having grafted maleimide polymers forming cross-linking between polybutadiene backbone segments. The resultant prepolymer can be subsequently cured to a hard resin by heating in the presence of a peroxide-free radical initiator to form cross-linking between vinyl polybutadiene structures through the pendant vinyl groups. The resultant hard resin provides strength retention at elevated temperatures and exhibits a flexibility and strength without being brittle.
    Type: Grant
    Filed: December 11, 1978
    Date of Patent: October 21, 1980
    Assignee: TRW Inc.
    Inventors: Robert J. Jones, Robert W. Vaughan, Robert A. Buyny, Michael K. O'Rell
  • Patent number: 4216297
    Abstract: Vinyl polybutadiene bisimide copolymers which are peroxide curable are provided by two methods of formation. In the first method a bisimide cross-linked vinyl polybutadiene prepolymer is formed by combining a high vinyl content polybutadiene providing pendant vinyl groups with a bisimide in the presence of a first free radical initiating catalyst. The resultant cross-linked prepolymer is cured to a hard resin by the formation of additional cross-linkages through the pendant vinyl groups by heating the prepolymer to a temperature of at least about 300.degree. F. in the presence of a second free radical initiating catalyst. The second method discloses a method wherein the bisimide cross-linkages are formed in situ. In the second method, a high vinyl content polybutadiene providing pendant vinyl groups is reacted with maleic anhydride to form a maleic anhydride vinyl polybutadiene adduct. The adduct is subsequently combined with an aromatic polyamine and a free radical initiating catalyst.
    Type: Grant
    Filed: February 13, 1978
    Date of Patent: August 5, 1980
    Assignee: TRW Inc.
    Inventors: Robert W. Vaughan, Michael K. O'Rell, Clyde H. Sheppard
  • Patent number: 3988561
    Abstract: Structurally stronger titanium articles are produced by a weld-bonding technique comprising fastening at least two plates of titanium together using spot-welding and curing an adhesive interspersed between the spot-weld nuggets. This weld-bonding may be employed to form lap joints or to stiffen titanium metal plates.
    Type: Grant
    Filed: January 2, 1975
    Date of Patent: October 26, 1976
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Robert W. Vaughan, John F. Creedon
  • Patent number: 3967091
    Abstract: Structurally stronger titanium articles are produced by a weld-bonding technique comprising fastening at least two plates of titanium together using spot-welding and applying a bead of adhesive along the edge of the resistance spot-welded joint which, upon heating, flows and fills the separation between the joint components.
    Type: Grant
    Filed: January 2, 1975
    Date of Patent: June 29, 1976
    Assignee: The United States of America as represented by the United States National Aeronautics and Space Administration
    Inventors: Robert W. Vaughan, Robert J. Jones
  • Patent number: 3953544
    Abstract: A low temperature curing polymeric adhesive composition may be made by reacting an amino alcohol having between 1 and 3 amino groups and between 2 and 5 hydroxyl groups with a stoichiometric amount of a carboxylic acid or derivative. Free radical catalysts and accelerators may be added to speed the cure of the adhesive. These adhesive resins can be cured at or near ambient room temperature and are highly desired for fabrication of bonded materials possessing long fatigue life because of reduced stresses that might be induced at higher cure temperatures. A generalized formula may be illustrated as follows: ##EQU1## WHERE R" may be hydrogen, alkyl, or cycloalkyl; R' may be hydrogen or alkyl; R is an alkyl; R.sub.1 may be hydrogen, an alkyl, or phenyl; m is an integer from 1 to 3; and n is an integer from 1 to 2.
    Type: Grant
    Filed: May 10, 1974
    Date of Patent: April 27, 1976
    Assignee: TRW Inc.
    Inventors: Robert J. Jones, Howard E. Green, Robert W. Vaughan
  • Patent number: D256679
    Type: Grant
    Filed: October 25, 1978
    Date of Patent: September 2, 1980
    Inventors: James G. Vaughan, Robert W. Vaughan