Patents by Inventor Robert Walczak

Robert Walczak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RORgamma modulators and uses thereof
    Patent number: 11974997
    Abstract: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: May 7, 2024
    Assignee: Genfit
    Inventors: Jean-Francois Delhomel, Enrico Perspicace, Zouher Majd, Peggy Parroche, Robert Walczak, Pascal Bonnet, Jade Fogha
  • DUAL HEAT EXCHANGER FOR HEAT PUMP SYSTEM
    Publication number: 20240118005
    Abstract: A heat exchanger for use in an outdoor environment with a heat pump system is provided. The heat exchanger includes a first set of tubes arranged in a parallel flow manner between a first manifold and a second manifold, wherein central straight portions of adjacent tubes are disposed with a space therebetween along each tube of the first set of tube between the first and second manifolds. A second set of tubes are arranged in a parallel flow manner between a third manifold and a fourth manifold, wherein central straight portions of adjacent tubes within the second set of tubes are at least partially disposed within the space between adjacent tubes of the first set of tubes. A fluid that flows through the first set of tubes additionally flows through the second set of tubes before the fluid returns to again flow through the first set of tubes.
    Type: Application
    Filed: October 11, 2022
    Publication date: April 11, 2024
    Inventors: Scott KENT, Robert Louis RUNK, Lindsey Lee LEITZEL, Szymon WALCZAK
  • METHODS OF TREATMENT OF LIVER FAILURE
    Publication number: 20240000754
    Abstract: The invention relates to the treatment or prevention of liver failure.
    Type: Application
    Filed: November 16, 2021
    Publication date: January 4, 2024
    Inventors: Philippe DELATAILLE, Robert WALCZAK, Corinne FOUCART, Vanessa LEGRY, Nicolas STANKOVIC VALENTIN, Simon DEBAECKER, Rémy HANF
  • IN VITRO MODEL OF LIVER STEATOHEPATITIS
    Publication number: 20230323308
    Abstract: The present invention relates to methods for preparing in vitro models of nonalcoholic steatohepatitis.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 12, 2023
    Inventors: GUILLAUME VIDAL, ROBERT WALCZAK
  • Pharmaceutical compositions for combination therapy
    Patent number: 11590108
    Abstract: The present invention relates to a combination of active ingredients for use in the treatment of diseases.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: February 28, 2023
    Assignee: Genfit
    Inventors: Emeline Descamps, Robert Walczak, Carole Belanger, Benoît Noel
  • PHOSPHATE DERIVATIVES OF RORGAMMA MODULATORS AND USES THEREOF
    Publication number: 20230039185
    Abstract: The present invention relates to phosphate derivatives of formula (I), and their therapeutic uses, preferably for treating a respiratory disease. The present invention further relates to pharmaceutical compositions and devices comprising such compounds.
    Type: Application
    Filed: December 17, 2020
    Publication date: February 9, 2023
    Inventors: JEAN-FRANÇOIS DELHOMEL, ROBERT WALCZAK, PEGGY PARROCHE, ANNE-MARIE SAVERET
  • COMBINATION THERAPY HAVING ANTIOXYDANT PROPERTIES
    Publication number: 20220401420
    Abstract: The present invention relates to novel uses of nitazoxanide, or analogues thereof.
    Type: Application
    Filed: October 27, 2020
    Publication date: December 22, 2022
    Inventors: NICOLAS STANKOVIC-VALENTIN, PEGGY PARROCHE, CORINNE FOUCART, ROBERT WALCZAK
  • COMBINATION THERAPY COMPRISING COMPOUNDS OF FORMULA (I) AND GLP-1 RECEPTOR AGONISTS
    Publication number: 20220362187
    Abstract: The present invention relates to a combination therapy comprising a PPAR agonist and a GLP-1 receptor agonist.
    Type: Application
    Filed: April 9, 2020
    Publication date: November 17, 2022
    Inventors: ROBERT WALCZAK, VANESSA LEGRY, EMELINE DESCAMPS
  • Combination comprising a PPAR agonist such as elafibranor and an acetyl-CoA carboxylase (ACC) inhibitor
    Patent number: 11484517
    Abstract: The present invention relates to a combination product and its use in therapy.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: November 1, 2022
    Assignee: GENFIT
    Inventors: Robert Walczak, Carole Belanger, Vanessa Legry, Benoît Noel, Emeline Descamps, Guillaume Vidal, Mathilde Walczak, Isabelle Delbaere
  • Combination of Elafibranor or derivatives thereof with an anti-NASH, anti-fibrotic or anti-cholestatic agent
    Patent number: 11478440
    Abstract: The present invention relates to a combination product and its use in therapy.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: October 25, 2022
    Assignee: GENFIT
    Inventors: Robert Walczak, Carole Belanger, Vanessa Legry, Benoît Noel, Emeline Descamps, Guillaume Vidal, Mathilde Walczak
  • METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
    Publication number: 20220323422
    Abstract: The present invention relates to a synergistic combination of active ingredients for use in the treatment of fibrotic diseases.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 13, 2022
    Inventors: Robert WALCZAK, Corinne FOUCART, Philippe DELATAILLE
  • Methods of treatment for cholestatic and fibrotic diseases
    Patent number: 11400078
    Abstract: The present invention relates to a synergistic combination of active ingredients for use in the treatment of fibrotic diseases.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: August 2, 2022
    Assignee: GENFIT
    Inventors: Robert Walczak, Corinne Foucart, Philippe Delataille
  • NITAZOXANIDE AND THIAZOLIDES FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH OXIDATIVE STRESS
    Publication number: 20220193042
    Abstract: The present invention relates to novel uses of nitazoxanide, or analogues thereof.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 23, 2022
    Inventors: Nicolas STANKOVIC-VALENTIN, Corinne FOUCART, Peggy PARROCHE, Robert WALCZAK
  • COMBINATION OF NITAZOXANIDE AND ELAFIBRANOR FOR THE TREATMENT OF IMMUNE DISEASES OR INFLAMMATION
    Publication number: 20220175737
    Abstract: The present invention relates to a combination product comprising (i) nitazoxanide (NTZ) or an analogue thereof, and (ii) a PPAR agonist, for use in the treatment of an immune diseases or inflammation.
    Type: Application
    Filed: April 7, 2020
    Publication date: June 9, 2022
    Inventors: Peggy PARROCHE, Robert WALCZAK
  • RORGAMMA MODULATORS AND USES THEREOF
    Publication number: 20220133716
    Abstract: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
    Type: Application
    Filed: October 5, 2021
    Publication date: May 5, 2022
    Inventors: Jean-Francois Delhomel, Enrico Perspicace, Zouher Majd, Peggy Parroche, Robert Walczak, Pascal Bonnet, Jade Fogha
  • IN VITRO MODEL OF LIVER STEATOSIS AND FIBROSING NON-ALCOHOLIC STEATOHEPATITIS
    Publication number: 20220056419
    Abstract: The present invention relates to compositions and methods for preparing in vitro models of non-alcoholic fatty liver disease, and more particularly of liver steatosis and fibrosing non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: December 18, 2019
    Publication date: February 24, 2022
    Inventors: GUILLAUME VIDAL, FLORIANE LIMOGE, JULIETTE DROUARD, ROBERT WALCZAK, CAROLE BELANGER
  • Pharmaceutical compositions for combination therapy
    Patent number: 11191749
    Abstract: The present invention relates to a combination product and its use in therapy.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: December 7, 2021
    Assignee: GENFIT
    Inventors: Dean Hum, Robert Walczak, Carole Belanger, Corinne Foucart
  • RORgamma modulators and uses thereof
    Patent number: 11160801
    Abstract: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: November 2, 2021
    Assignee: Genfit
    Inventors: Jean-Francois Delhomel, Enrico Perspicace, Zouher Majd, Peggy Parroche, Robert Walczak, Pascal Bonnet, Jade Fogha
  • PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY
    Publication number: 20210275504
    Abstract: The present invention relates to a combination product and its use in therapy.
    Type: Application
    Filed: May 10, 2021
    Publication date: September 9, 2021
    Inventors: Corinne FOUCART, Robert WALCZAK, Carole BELANGER, Benoît NOEL
  • Methods of treatment for cholestatic and fibrotic diseases
    Patent number: 11103484
    Abstract: The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or 2-hydroxy-N-(5-nitro-2-thiazolyl)benzamide (Tizoxanide) for treating cholestatic and fibrotic diseases.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: August 31, 2021
    Assignee: Genfit
    Inventors: Raphael Darteil, Robert Walczak, Carole Belanger, Emilie Negro, Pierre Daubersies, Philippe Delataille