Abstract: A thrust reverser cascade of an aircraft engine comprises a frame and a vane overmolded onto the frame. The frame and the vane each comprise reinforcement fibers in a thermoplastic matrix. A method is disclosed for manufacturing the thrust reverser cascade or another part comprising an aerodynamic surface configured to interact with a flow of fluid. The method comprises providing a first portion of the part and overmolding a second portion of the part onto the first portion where the second portion includes the aerodynamic surface.

Abstract: The present disclosure is directed towards improved systems and methods for large-scale production of nanoparticles used for delivery of therapeutic material. The apparatus can be used to manufacture a wide array of nanoparticles containing therapeutic material including, but not limited to, lipid nanoparticles and polymer nanoparticles. In certain embodiments, continuous flow operation and parallelization of microfluidic mixers contribute to increased nanoparticle production volume.

Abstract: Immobilized proteases for activation of the zymogen form of transglutaminase are disclosed.

Abstract: A vehicle assembly includes a cargo bed having a first and a second sidewall. A rail assembly is disposed on the first sidewall. The rail assembly is movable between an extended position and a retracted position relative to the first sidewall. An actuator system raises and lowers the rail assembly to move the rail assembly between the extended position and the retracted position.

Abstract: An example vehicle includes a frame and a body panel attached to the frame and providing an exterior surface of the vehicle. The body panel includes a flexible fabric material. This provides a number of benefits, including providing a resilient, lightweight, and customizable body panel. These and other benefits will be appreciated from the detailed description and drawings.

Abstract: A vehicle assembly includes a cargo bed having a first and a second sidewall. A rail assembly is disposed on the first sidewall. The rail assembly is movable between an extended position and a retracted position relative to the first sidewall. An actuator system raises and lowers the rail assembly to move the rail assembly between the extended position and the retracted position.

Abstract: A method of producing an osteoinductive composition for in vivo use, in which the method includes obtaining bone tissue; cleaning the bone tissue with a plurality of washes; milling, grinding, and/or cutting the cleaned bone tissue into a plurality of bone pieces or fibers of a desired size; and demineralizing the plurality of bone pieces or fibers of a desired size to expose one or more native bone proteins, with demineralizing including combining the plurality of bone pieces or fibers in a reaction vessel with an ionic acid solution, soaking the plurality of bone pieces or fibers in the ionic acid solution, and exposing the one or more native proteins in the bone pieces or fibers.

Abstract: Technologies are generally provided for devices, systems, and methods to provide spinal fixation, spinal stabilization, and/or spinal fusion. Example devices may include a first end and a second end with a middle portion extending between the first and second end. The first end may be configured to be in contact with a portion of a first or upper vertebra and the second end may be configured to be in contact with a portion of a second or lower vertebra in an adjacent vertebral pair. Portions of the vertebra which may be in contact with the device may include lamia, processes, vertebral bodies, and facet joints. The example devices may include bone engagement features, such as screws or similar fasteners, to enhance stabilization and fixation when in contact with the vertebrae. Additionally, the devices may include a bone integration feature to promote bone growth and to facilitate fusion between the vertebrae.

Abstract: This disclosure relates to a vehicle with a body panel including a flexible fabric. An example vehicle includes a frame and a body panel attached to the frame and providing an exterior surface of the vehicle. The body panel includes a flexible fabric material.

Abstract: An aerodynamics control system for a vehicle may include a repositionable aerodynamic device disposed at a portion of the vehicle, a controller operably coupled to components or sensors of the vehicle to receive information including vehicle performance data and position information for the aerodynamic device, and a vehicle location sensor determining location information for the vehicle. The controller stores the vehicle performance data and the position information in association with the location information for each of a plurality of locations. Responsive to detecting an approach of the vehicle to one of the locations, the controller provides a control instruction to position the aerodynamic device based on recorded vehicle performance data and recorded position information associated with the one of the locations.

Abstract: A structural assembly of an aircraft has a fastener extending into first and second structural members. A washer is disposed between the fastener and one of the structural members to electrically insulate the fastener and the structural members. The washer has a core of reinforcement fibers supported in a thermoplastic matrix material. Electrically-insulating outer layers of glass fibers overlay the core.

Abstract: A device adapted to be positioned between two bone regions, the device comprising at least one wall defining at least one interior cavity, and, a load arrangement extending from the wall and comprising at least one interacting feature configured to load material positioned within the cavity by interacting with either a second interacting feature or the wall.

Abstract: Technologies are generally provided for devices, systems, and methods to provide spinal fixation, spinal stabilization, and/or spinal fusion. Example devices may include a first end and a second end with a middle portion extending between the first and second end. The first end may be configured to be in contact with a portion of a first or upper vertebra and the second end may be configured to be in contact with a portion of a second or lower vertebra in an adjacent vertebral pair. Portions of the vertebra which may be in contact with the device may include lamina, processes, vertebral bodies, and facet joints. The example devices may include bone engagement features, such as screws or similar fasteners, to enhance stabilization and fixation when in contact with the vertebrae. Additionally, the devices may include a bone integration feature to promote bone growth and to facilitate fusion between the vertebrae.

Abstract: A device adapted to be positioned between two bone regions, the device comprising a body having a stabilising arrangement configured such that bone growing from one bone region toward the other engages the stabilising arrangement of the device

Abstract: A device adapted to be positioned between two bone regions, the device comprising a body having a stabilising arrangement configured such that bone growing from one bone region toward the other engages the stabilising arrangement of the device.

Abstract: A fixation device comprising a shaft extending from a leading end to a trailing end, an aperture being eccentric from a centre of the trailing end, and, a channel extending from the aperture and along at least a portion of an external surface of the body toward the leading end, the aperture and channel being aligned to form a passage.

Abstract: Technologies are generally provided for devices, systems, and methods to provide spinal fixation, spinal stabilization, and/or spinal fusion. Example devices may include a first end and a second end with a middle portion extending between the first and second end. The first end may be configured to be in contact with a portion of a first or upper vertebra and the second end may be configured to be in contact with a portion of a second or lower vertebra in an adjacent vertebral pair. Portions of the vertebra which may be in contact with the device may include lamina, processes, vertebral bodies, and facet joints. The example devices may include bone engagement features, such as screws or similar fasteners, to enhance stabilization and fixation when in contact with the vertebrae. Additionally, the devices may include a bone integration feature to promote bone growth and to facilitate fusion between the vertebrae.

Abstract: A structural assembly of an aircraft has a fastener extending into first and second structural members. A washer is disposed between the fastener and one of the structural members to electrically insulate the fastener and the structural members. The washer has a core of reinforcement fibers supported in a thermoplastic matrix material. Electrically-insulating outer layers of glass fibers overlay the core.

Abstract: An Unloader assembly to control load distribution about a joint is disclosed. The assembly including an upper collar attachable above the joint and a lower collar attached below the joint, and a hinge positioned between the upper attachment and the lower attachment. The Unloader further includes a compression assembly includes an arm attached at one end to the hinge and a housing into which the arm is slidable. The housing further includes a bushing and a variable resistance beam positioned between the arm and the bushing. The variable resistance beam provides a variable degree of rigidity to provide different levels of resistance to compression.

Abstract: An active footwear suspension system is disclosed. The footwear system provides dynamic suspension using at least one or more variable resistance beams. At least one or more VRB from an anchor plate positioned forward of and/or aft of an arch section of the footwear, thus providing selectable suspension to the wearer. The selected rotation of the VRBs from a first position to a second position provides customized suspension between a minimum resistance to a maximum resistance per zone.