Abstract: A shower system includes a shower waterway and a fluid control valve. The shower waterway is configured to be coupled to a shower device. The fluid control valve is coupled to the shower waterway and comprises a valve body and a piston. The valve body includes a chamber and a reservoir. The piston is slidably coupled to the valve body and fluidly separates the chamber from the reservoir. The chamber includes a compressible gas. The piston is configured to slidably translate within the valve body to compress the compressible gas in response to a water pressure fluctuation in the shower waterway.

Abstract: Compositions and methods useful in inhibiting proliferation of CA IX+preneoplastic or neoplastic cells in a mammal are provided. The compositions are antagonist anti-CA IX antibodies and other inhibitory agents that target carbonic anhydrase activity of CA IX on these cells. The antagonist anti-CA IX antibodies or antigen-binding fragments thereof are specifically reactive with an inhibitory epitope of CA IX or biologically active variant thereof. Formation of an antibody-antigen complex between the antagonist anti-CA IX antibodies or antigen-binding fragments thereof and the respective inhibitory epitopes results in inhibition of carbonic anhydrase activity of CA IX or biologically active variant thereof. Other small molecule agents that inhibit carbonic anhydrase activity of CA IX or biologically active variant thereof and screening assays for identifying such agents are also provided.

Abstract: A system, method, apparatus and product for designing, on a display device, a geometric shape is disclosed. The method comprises the steps of displaying an initial set of similarly structured model exemplars on a display device, selecting a chosen set of models from the initial set of similarly structured model exemplars to apply to a model mix, mixing the set of models consisting of a first portion and a second portion to form a currently displayed shape, providing on the display device at least one selectable feature for manipulating the currently displayed shape, and applying a constraint of the selectable feature to the displayed shape to update both the first portion and the second portion of the currently displayed shape into a new geometric shape design. In a particular implementation, the first portion of the geometric shape is an automobile and the second portion is a standardized human occupant representation.

Abstract: A system, method, apparatus and product for designing, on a display device, a geometric shape is disclosed. The method comprises the steps of displaying an initial set of similarly structured model exemplars on a display device, selecting a chosen set of models from the initial set of similarly structured model exemplars to apply to a model mix, mixing the set of models to form a currently displayed shape, providing on the display device at least one selectable feature for manipulating the currently displayed shape, and applying at least one constraint of the selectable feature to the currently displayed shape to update the currently displayed shape into a new geometric shape design.

Abstract: In accordance with one exemplary embodiment, there is provided a welding torch that includes features facilitating aligned assembly of various components of the welding torch with respect to one another. For example, the welding torch includes a nipple that carries a pin member extending from both an inner peripheral surface and an outer peripheral of a sleeve of the nipple. This pin engages with a slot on a coupling member and a slot on a neck assembly, thereby facilitating proper alignment of the neck assembly, coupling member, and nipple with respect to one another. Moreover, the engagement between the pin member and the slots block pivotal displacement of neck assembly, coupling member, and neck assembly with respect to one another. Advantageously, the use of a single pin member for both slots presents a more judicious construction, leading to reduced manufacturing costs, for instance.

Abstract: In accordance with one embodiment, there is provided a welding torch nipple for coupling a welding cable and neck assembly to one another. The exemplary nipple includes two hollow tubes: an inner tube disposed in an outer tube. The inner tube includes features that facilitate mating with a welding cable and the outer tube is configured to receive a neck assembly. A dielectric layer disposed between the inner and outer tubes electrically isolates the outer tube from the inner tube, thereby protecting a user from electrical shock, for instance. The dielectric layer includes a stem portion that extends radially into the outer tube, blocking axial separation of the outer tube and the dielectric layer.

Abstract: A polypeptide containing an anchor region, a protease recognition site, and a detectable signal region can be produced recombinantly and directly attached to a solid support. The polypeptide is useful for screening protease regulators, especially protease inhibitors.

Abstract: In accordance with one embodiment, the present invention provides a welding torch nipple for coupling a welding cable and neck assembly to one another. The exemplary nipple includes two hollow tubes: an inner tube disposed in an outer tube. The inner tube includes features that facilitate mating with a welding cable and the outer tube is configured to receive a neck assembly. A dielectric layer disposed between the inner and outer tubes electrically isolates the outer tube from the inner tube, thereby protecting a user from electrical shock, for instance. The dielectric layer includes a stem portion that extends radially into the outer tube, blocking axial separation of the outer tube and the dielectric layer.

Abstract: In accordance with one exemplary embodiment, the present invention provides a welding torch that includes features facilitating aligned assembly of various components of the welding torch with respect to one another. For example, the welding torch includes a nipple that carries a pin member extending from both an inner peripheral surface and an outer peripheral of a sleeve of the nipple. This pin engages with a slot on a coupling member and a slot on a neck assembly, thereby facilitating proper alignment of the neck assembly, coupling member, and nipple with respect to one another. Moreover, the engagement between the pin member and the slots block pivotal displacement of neck assembly, coupling member, and neck assembly with respect to one another. Advantageously, the use of a single pin member for both slots presents a more judicious construction, leading to reduced manufacturing costs, for instance.

Abstract: A vehicular secondary control interface is disclosed. In an exemplary embodiment, the control interface includes a plurality of category input devices for selecting a function category, with each of the function categories having one or more selectable secondary functions associated therewith. A display area displays the selectable secondary functions associated with a selected function category, highlighting the active secondary function, and further displays parameter information regarding the active secondary functions. In addition, a selection input device adjustably selects the secondary functions associated with a selected function category, and an adjustment input device controls the active secondary function associated with the selected function category.

Abstract: A liquid-cooled welding torch assembly for use in robotic welding that includes a body tube with a set of male connectors, the body tube guiding an electrode, and a flow of coolant to a welding tip. A supply cable adapter including a set of female connectors corresponding to the set of male connectors. At least one of the male connectors includes a rigid tube with a plurality of axially compressible and radially expandable sealing members coaxially and slidably disposed about the rigid tube, whereby the plurality of axially compressible and radially expandable sealing members expand to create a seal between the at least one of the male connectors and a corresponding one of the set of female connectors.