Abstract: Calcium-strontium-hydroxyphosphate (strontium-apatite-) cement preparations are described, comprising a powder mixture, which contains molar quantities of the components calcium (Ca), strontium (Sr) and phosphate (P) in the mixture in the ranges 1.00<Ca/P?1.50 and 0<Sr/P<1.5, together with an alkali salt or an ammonium salt of phosphoric acid, and with water and/or an aqueous solution. The powder mixture particularly contains, as the Ca-component, Ca3(PO4)2 (TCP), and as the Sr-component SrHPO4 and/or Sr3(PO4)2 and optionally additional SrCO3. As the aqueous mixing solution for the formation of the strontium-apatite cement, an aqueous solution of an alkali salt or an ammonium salt of the phosphoric acid is suitable.

Abstract: A self-foaming bone cement is described herein. In one variation, the bone cements include a self setting calcium phosphate cement formulation which when cured, forms macroscopic pores of varying sizes and densities with sufficient surface area to provide substantial regions for bone turnover.

Abstract: The invention relates to methods, compositions, kits and systems for determining one or more cement material properties. In one variation, a color change agent is introduced into bone cement to allow a physician to determine when a cement has the desired viscosity for insertion into a patient. In another variation, the composition comprises one or more curable bioactive agents and one or more color change agents. The curable bioactive agent(s) may be one or more bone cement(s). These Bone cements contain a color change agent that allows a physician to tell when the cement has reached the property viscosity for insertion of the bone cement into a patient at the bone site.

Abstract: Calcium-strontium-hydroxyphosphate (strontium-apatite-) cement preparations are described, comprising a powder mixture, which contains molar quantities of the components calcium (Ca), strontium (Sr) and phosphate (P) in the mixture in the ranges 1.00<Ca/P?1.50 and 0<Sr/P<1.5, together with an alkali salt or an ammonium salt of phosphoric acid, and with water and/or an aqueous solution. The powder mixture particularly contains, as the Ca-component, Ca3(PO4)2 (TCP), and as the Sr-component SrHPO4 and/or Sr3(PO4)2 and optionally additional SrCO3. As the aqueous mixing solution for the formation of the strontium-apatite cement, an aqueous solution of an alkali salt or an ammonium salt of the phosphoric acid is suitable.

Abstract: Disclosed herein is a composition suitable for use in spinal surgery. The composition generally includes a reaction product or settable mixture of first and second components, the first component including a spray-dried inorganic filler, a radical donor, and a pre-polymerized vinyl polymer, and the second component including a radical scavenger, a diluent, a polymerization accelerator, and a reactive monomer. Furthermore, disclosed herein is a method of making the composition, which generally includes mixing the first and second components under conditions suitable to form a curable reaction product.

Abstract: The apparatus for production of mixtures from two components has a container for each and devices to combine the components in the mixing space and for extrusion of the mixture. The powdered component (4) is situated in the lower part of the inner space (21), which is sealed by a bottom (10). This carries a nozzle (2) with closure membrane (3). The inner space (21) is closed on the top by the lower wall (6) and the sliding seal (8). The liquid component (9) is situated in the inner space (18) of the inner hollow cylinder (5). This is closed on the top by the upper wall (11). The lower and upper wall (6) and (11) each have an opening with sealing lips (7) and (12) that are closed by parts of the mixing rod (15). A torus (20), a section with smaller diameter (19), a mixing disk (22), as well as a mandrel (24), are present on the lower part of the mixing rod (15).

Abstract: A bone cement comprises a powdery component including calcium phosphate and an aqueous liquid component. A radiopaque material is added to at least one of the powder and liquid components, and the components may be combined into a pasty substance for application to bone.

Abstract: The present invention is a tinted, optical adhesive for use in making plasma display filters comprising a substantially acid free, pressure-sensitive adhesive (PSA) containing a narrow-band, visible spectrum dye (e.g. less than 30 nm bandwidth) and a broader-band, near infra-red spectrum dye (e.g. greater than 200 nm), the second dye providing enhanced thermal stability as well as near infra-red (NIR) blocking. Further, acid-free adhesives offer improved stability of light control dyes. In the present invention, porphyrin-based dyes combined with acrylate-based, pressure-sensitive optical adhesives are preferred. Invention offers reduced number of functional layers in an optical filter structure as well as reduced number of manufacturing (lamination) steps in the optical filter/plasma display assembly process.

Abstract: The present invention relates to novel bone substitute compositions and methods of use. It further encompasses the use of these novel bone substitute compositions for bone augmentation and the treatment of disease conditions. The invention also contemplates a kit including bone substitute compositions and a percutaneous delivery device.

Abstract: Calcium-strontium-hydroxyphosphate (strontium-apatite-) cement preparations are described, comprising a powder mixture, which contains molar quantities of the components calcium (Ca), strontium (Sr) and phosphate (P) in the mixture in the ranges 1.00<Ca/P?1.50 and 0<Sr/P<1.5, together with an alkali salt or an ammonium salt of phosphoric acid, and with water and/or an aqueous solution. The powder mixture particularly contains, as the Ca-component, Ca3(PO4)2 (TCP), and as the Sr-component SrHPO4 and/or Sr3(PO4)2 and optionally additional SrCO3. As the aqueous mixing solution for the formation of the strontium-apatite cement, an aqueous solution of an alkali salt or an ammonium salt of the phosphoric acid is suitable.

Abstract: The apparatus for production of mixtures from two components has a container for each and devices to combine the components in the mixing space and for extrusion of the mixture. The powdered component (4) is situated in the lower part of the inner space (21), which is sealed by a bottom (10). This carries a nozzle (2) with closure membrane (3). The inner space (21) is closed on the top by the lower wall (6) and the sliding seal (8). The liquid component (9) is situated in the inner space (18) of the inner hollow cylinder (5). This is closed on the top by the upper wall (11). The lower and upper wall (6) and (11) each have an opening with sealing lips (7) and (12) that are closed by parts of the mixing rod (15). A torus (20), a section with smaller diameter (19), a mixing disk (22), as well as a mandrel (24), are present on the lower part of the mixing rod (15).

Abstract: The invention describes biodegradable calcium phosphate cements, in particular mixtures of calcium phosphate-containing powders of different stoichiometric composition, the precipitated hydroxylapatite present being a cation-deficient hydroxylapatite of the formula 1, with the result that the mixtures have improved properties with regard to compressive strength.

Abstract: The invention relates to an injectable curable bone cement paste based on bioresorbable hydroxyapatite-like compounds comprising calcium phosphate, which contains a cationic antibiotic in the form of a salt, preferably of its sulfate, the curable biodegradable bone cement releasing the antibiotic in biologically active concentrations with depot-like action over a long period of time. The bone cements according to the invention are suitable for the treatment of infectious inflammations of the bone and of the bone marrow, in particular as a result of bone defects and bone fractures.

Abstract: Reactive systems for polymerizing ethylenically unsaturated compounds comprising a first component, comprised of ethylenically unsaturated compounds capable of polymerization, and a second component of a hardener system comprised of organoboron compounds which are stabilized with suitable oligomers. An organic peroxide (perester, hydroperoxide, perether and/or peranhydride) is admixed with the compounds. These components are mixed to form a polymer. The reactive system reaches full strength in reduced time with the use of the organic peroxide and are suitable for joining hard body materials in human or animal tissue, in particular in the surgical and/or dental sector, in the production of body-absorbable or body-resistant adhesives, cements, and/or filling compounds and for forming synthetic material moldings.

Abstract: Reactive systems for polymerizing ethylenically unsaturated compounds comprising a first component, comprised of ethylenically unsaturated compounds capable of polymerization, and a second component of a hardener system comprised of organoboron compounds which are stabilized with suitable oligomers. An organic peroxide (perester, hydroperoxide, perether and/or peranhydride)is admixed with the compounds. These components are mixed to form a polymer. The reactive system reaches full strength in reduced time with the use of the organic peroxide and are suitable for joining hard body materials in human or animal tissue, in particular in the surgical and/or dental sector, in the production of body-absorbable or body-resistant adhesives, cements, and/or filling compounds and for forming synthetic material moldings.

Abstract: The present invention relates to improved bone sealants for staunching local haemorrhages on bones, which are characterized in that the bone sealant consists of a polyester oligomer synthesized from polyol, lactide and glycolide, and water-soulble polymers.

Abstract: The invention describes biodegradable calcium phosphate cements, in particular mixtures of calcium phosphate-containing powders of different stoichiometric composition, the precipitated hydroxylapatite present being a cation-deficient hydroxylapatite of the formula 1, with the result that the mixtures have improved properties with regard to compressive strength.

Abstract: Described herein are methods for preparing bioabsorbable polymerization products having interconnecting pore structure by polymerizing compositions containing ethylene glycol- or glycero-oligoester(meth)acrylates monomers and, optionally, other components. The polymerization products are particularly useful for dental lacquers, dental inlays and shaped articles which are bioabsorbable and exhibit an interconnecting pore structure.

Abstract: The invention relates to biocement pastes based on tricalcium phosphate and materials which are suitable for preventing or reducing the tendencies of the settable pastes to disintegrate and for improving their cohesion properties, with the result that improved processing of said pastes in the preparation of synthetic bone cements is ensured.