Patents by Inventor Robert William Van Leen

Robert William Van Leen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression and purification of human interleukin-3 and muteins thereof
    Patent number: 6384194
    Abstract: Methods are provided for improved production of hIL-3 either in glycosylated form from mammalian and yeast cells or in unglycosylated form from prokaryotes. Recombinantly produced human IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion exchange chromatography and gel filtration.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 7, 2002
    Assignee: DSM N.V.
    Inventors: Lambertus Christiaan Johannes Dorssers, Gerard Wagemaker, Yvonne Johanna Vos, Robert William Van Leen, Maria Ludovicus Nicolaas Persoon